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Evolutionary Concepts in Immunology (Hardcover, 1st ed. 2019): Robert Jack, Louis Du Pasquier Evolutionary Concepts in Immunology (Hardcover, 1st ed. 2019)
Robert Jack, Louis Du Pasquier
R2,493 Discovery Miles 24 930 Ships in 12 - 17 working days

Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhansky's famous slogan, "Nothing in biology makes sense except in the light of evolution", this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.

Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations (Hardcover, 1st ed. 2015): Ellen Hsu, Louis Du Pasquier Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations (Hardcover, 1st ed. 2015)
Ellen Hsu, Louis Du Pasquier
R4,708 Discovery Miles 47 080 Ships in 12 - 17 working days

This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.

Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations (Paperback, Softcover reprint of the original 1st ed.... Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations (Paperback, Softcover reprint of the original 1st ed. 2015)
Ellen Hsu, Louis Du Pasquier
R5,164 Discovery Miles 51 640 Ships in 10 - 15 working days

This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.

Evolutionary Concepts in Immunology (Paperback, 1st ed. 2019): Robert Jack, Louis Du Pasquier Evolutionary Concepts in Immunology (Paperback, 1st ed. 2019)
Robert Jack, Louis Du Pasquier
R1,829 Discovery Miles 18 290 Ships in 10 - 15 working days

Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhansky's famous slogan, "Nothing in biology makes sense except in the light of evolution", this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.

Cours de Dessin Professé À l'École La Martinière. 2e Édition (Paperback): Louis Du Pasquier Cours de Dessin Professé À l'École La Martinière. 2e Édition (Paperback)
Louis Du Pasquier
R751 Discovery Miles 7 510 Ships in 10 - 15 working days
Cours de Dessin Professe A l'Ecole La Martiniere (French, Paperback): Louis Du Pasquier Cours de Dessin Professe A l'Ecole La Martiniere (French, Paperback)
Louis Du Pasquier
R501 Discovery Miles 5 010 Ships in 10 - 15 working days
Cours de Dessin Professe A l'Ecole La Martiniere. Atlas (French, Paperback): Louis Du Pasquier Cours de Dessin Professe A l'Ecole La Martiniere. Atlas (French, Paperback)
Louis Du Pasquier
R380 Discovery Miles 3 800 Ships in 10 - 15 working days
Quelques Opinions Sur l'Ecole La Martiniere, Refutees (French, Paperback): Louis Du Pasquier Quelques Opinions Sur l'Ecole La Martiniere, Refutees (French, Paperback)
Louis Du Pasquier
R348 Discovery Miles 3 480 Ships in 10 - 15 working days
Cours de Dessin Professe A L'Ecole de La Martiniere... (French, Paperback): Louis Du Pasquier Cours de Dessin Professe A L'Ecole de La Martiniere... (French, Paperback)
Louis Du Pasquier
R871 R733 Discovery Miles 7 330 Save R138 (16%) Ships in 10 - 15 working days

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Cours De Dessin Professe a L'ecole De La Martiniere 2 Louis Dupasquier Perrin, 1852

Commentationes algebraicae ad theoriam combinationum et probabilitatum pertinentes (French, Latin, German, Hardcover, 1923... Commentationes algebraicae ad theoriam combinationum et probabilitatum pertinentes (French, Latin, German, Hardcover, 1923 ed.)
Leonhard Euler; Edited by Louis Du Pasquier
R3,466 Discovery Miles 34 660 Ships in 12 - 17 working days
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