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Selected as a Doody's Core Title for 2022! One of the world's most
widely read gynecology texts for nearly 50 years, Speroff 's
Clinical Gynecologic Endocrinology and Infertility provides a
complete explanation of the female endocrine system and offers
practical guidance for evaluation and treatment of common
disorders. In this fully revised ninth edition, the editorial and
author team from Yale School of Medicine have assumed the reins of
Dr. Speroff's landmark work, retaining the clear, concise writing
style and illustrations that clarify and explain complex concepts.
This classic text remains indispensable for students, residents,
and clinicians working in reproductive endocrinology and
infertility, bringing readers up to date with recent advances that
have occurred in this fast-changing field. Remains the definitive
text on reproductive endocrinology, offering authoritative coverage
of reproductive physiology, clinical endocrinology, contraception,
and infertility. Contains two new chapters on transgender medicine
and fertility preservation. Features many full-color illustrations,
algorithms, and tables throughout. Retains Dr. Speroff's clear,
user-friendly writing style while ensuring content is up to date
with today's best clinical practices. Enrich Your eBook Reading
Experience Read directly on your preferred device(s), such as
computer, tablet, or smartphone. Easily convert to audiobook,
powering your content with natural language text-to-speech.
Presenting an overview of the current understanding of the
pathophysiology of PCOS and a paradigm for the clinical evaluation
and management of the disorder, Polycystic Ovary Syndrome is
written in an easy to digest, concise format that, with bulleted
key points introducing each chapter, is suitable for the trainee
and the busy clinician. The breadth and depth of coverage of
today's queries and controversies will be of particular interest to
the specialist and researcher. An international group of leading
experts addresses the varied etiologies of PCOS, comprehensively
covering the contemporary treatment approaches and long-term
implications of PCOS, a common yet poorly understood disorder.
Chapters on treatment will be of particular relevance to the
clinician and the trainee as they cover conventional therapies,
lifestyle, and diet, as well as address emerging strategies such as
the use of statins and surgery in PCOS management. Spanning the
breadth of clinical presentations and morbidities related to the
diagnosis of PCOS, Polycystic Ovary Syndrome is an exceptional
resource for primary care providers, gynecologists, reproductive
endocrinologists, and others involved in the care of these
patients, and provides the essential tools to aid clinicians in
initiating a timely diagnostic workup and appropriate interventions
to address both the immediate and long-term sequelae related to
PCOS.
Now in a completely newly revised and expanded second edition, this
comprehensive text presents the current state of the art in our
understanding and management of polycystic ovary syndrome (PCOS),
the most common hormonal disorder of reproductive aged women. The
numerous bothersome symptoms of PCOS include menstrual
irregularities, hirsutism, acne, scalp hair thinning, weigh excess
and infertility; additionally, as they age, women with PCOS are at
a higher risk for metabolic abnormalities such as diabetes and
dyslipidemias, as well as for cardiovascular disease and even
certain cancers. Despite improvements in our understanding of this
condition, the exact cause/s of PCOS remain elusive; genetic,
hormonal, metabolic and environmental underpinnings are all
suggested as relevant. All chapters have been updated, with eight
new chapters added across seven thematic sections. Part one
discusses the epidemiology of PCOS in both adults and adolescents.
Part two covers the pathophysiology of PCOS, including genetics,
the hypothalamo-pituitary-ovarian and the
hypothalamo-pituitary-adrenal axes, insulin resistance,
inflammation, and obesity. The next three sections present the
various management strategies, medical and surgical, for harnessing
the symptomatology, including PCOS-related infertility; these
chapters include added case material to provide real-world examples
of the treatments in action and their efficacy. Part six covers the
comorbidities that women with PCOS commonly encounter, such as
issues of mental health, sleep disturbances, endometrial
hyperplasia, and cancer, as well as examines the economic burden of
PCOS. The final section discusses emerging concepts surrounding
possible mechanisms and potential therapeutic approaches to PCOS,
including angiogenic dysfunction, the role of vitamin D, future
potential therapies to targeted AMH signaling. The closing chapter,
by familiarizing the readers with the intergenerational
implications of PCOS and by raising awareness of potential "ripple
effects", aims at alerting the community on a need for vigilance as
regards the health of PCOS progeny. With contributions from leaders
in the field, Polycystic Ovary Syndrome, Second Edition remains the
gold-standard text on this common medical condition and a valuable
resource for the wide range of healthcare professionals engaged in
caring for the women with PCOS (including but not limited to
reproductive endocrinologists, gynecologists, family physicians,
dermatologists, mental health professionals), for the aspiring
women's health providers of tomorrow, and for the researchers who
are striving to unravel the mysteries of the complex entity that
PCOS is.
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