This volume presents a compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition. The techniques described provide the researcher with a diverse and comprehensive set of tools for the study of telomerase inhibition. The volume is aimed at biochemists, molecular biologists, cancer researchers, and geneticists.

This book aims to establish the position of the sidekick character in the crime and detective fiction literary genres. It re-evaluates the traditional view that the sidekick character in these genres is often overlooked as having a small, generic or singular role-either to act as the foil to the detective in order to accentuate their own abilities at solving crimes, or else to simply tell the story to the reader. Instead, essays in the collection explore the representations and functions of the detective's sidekick across a range of forms and subgenres of crime fiction. By incorporating forms such as children's detective fiction, comics and graphic novels and film and television alongside the more traditional fare of novels and short stories, this book aims to break down the boundaries that sometimes exist between these forms, using the sidekick as a defining thread to link them together into a wider conceptual argument that covers a broad range of crime narratives.

This book maps the development of the boy detective in British children's literature from the mid-nineteenth to the early-twentieth century. It explores how this liminal figure - a boy operating within a man's world - addresses adult anxieties about boyhood and the boy's transition to manhood. It investigates the literary, social and ideological significance of a vast array of popular detective narratives appearing in 'penny dreadfuls' and story papers which were aimed primarily at working-class boys. This study charts the relationship between developments in the representation of the fictional boy detective and changing expectations of and attitudes towards real-life British boys during a period where the boy's role in the future of the Empire was a key concern. It emphasises the value of the early fictional boy detective as an ideological tool to condition boy readers to fulfil adult desires and expectations of what boyhood and, in the future, proper manhood should entail. It will be of particular importance to scholars working in the fields of children's literature, crime fiction and popular culture.

This volume brings together a series of studies concerned with aspects of the archaeology of burial in early medieval England and Wales during the period c. A.D. 400-1100. The demographic composition of cemeteries, burial rites and mortuary behaviour are considered alongside the political and landscape context of burial, all topics which are recent developments in the field of burial archaeology in Britain. Students and researchers will find the theoretical and methodological approaches of use to their own studies, whilst those seeking an understanding of the trajectories of change in patterns of burial through the Anglo-Saxon period will find it the first summary of its kind. Besides offering individual studies, the volume reviews the early medieval burial archaeology of Britain and identifies areas of future research.

This book aims to establish the position of the sidekick character in the crime and detective fiction literary genres. It re-evaluates the traditional view that the sidekick character in these genres is often overlooked as having a small, generic or singular role-either to act as the foil to the detective in order to accentuate their own abilities at solving crimes, or else to simply tell the story to the reader. Instead, essays in the collection explore the representations and functions of the detective's sidekick across a range of forms and subgenres of crime fiction. By incorporating forms such as children's detective fiction, comics and graphic novels and film and television alongside the more traditional fare of novels and short stories, this book aims to break down the boundaries that sometimes exist between these forms, using the sidekick as a defining thread to link them together into a wider conceptual argument that covers a broad range of crime narratives.

Crime Fiction in the City: Capital Crimes expands upon previous studies of the urban space and crime by reflecting on the treatment of the capital city, a repository of authority, national identity and culture, within crime fiction. This wide-ranging collection looks at capital cities across Europe, from the more traditional centres of power - Paris, Rome and London - to Europe's most northern capital, Stockholm, and also considers the newly devolved capitals, Dublin, Edinburgh and Cardiff. The texts under consideration span the nineteenth-century city mysteries to contemporary populist crime fiction. The collection opens with a reflective essay by Ian Rankin and aims to inaugurate a dialogue between Anglophone and European crime writing; to explore the marginalised works of Irish and Welsh writers alongside established European crime writers and to interrogate the relationship between fact and fiction, creativity and criticism, within the crime genre.