This book constitutes the refereed proceedings of the first MICCAI Workshop, ISGIE 2022, Imaging Systems for GI Endoscopy, and the Fourth MICCAI Workshop, GRAIL 2022, GRaphs in biomedicAL Image and analysis, held in conjunction with MICCAI 2022, Singapore, September 18, 2022. ISGIE 2022 accepted 6 papers from the 8 submissions received.This workshop focuses on novel scientific contributions to vision systems, imaging algorithms as well as the autonomous system for endorobot for GI endoscopy. This includes lesion and lumen detection, as well as 3D reconstruction of the GI tract and hand-eye coordination. GRAIL 2022 accepted 6 papers from the 10 submissions received. The workshop aims to bring together scientists that use and develop graph-based models for the analysis of biomedical images and to encourage the exploration of graph-based models for difficult clinical problems within a variety of biomedical imaging contexts.

The book comprises three parts. The first part provides the state-of-the-art of robots for endoscopy (endorobots), including devices already available in the market and those that are still at the R&D stage. The second part focusses on the engineering design; it includes the use of polymers for soft robotics, comparing their advantages and limitations with those of their more rigid counterparts. The third part includes the project management of a multidisciplinary team, the health cost of current technology, and how a cost-effective device can have a substantial impact on the market. It also includes information on data governance, ethical and legal frameworks, and all steps needed to make this new technology available.