0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
Status
Brand

Showing 1 - 25 of 427 matches in All Departments

Research Handbook on Services Management (Hardcover): Mark M. Davis Research Handbook on Services Management (Hardcover)
Mark M. Davis
R5,706 Discovery Miles 57 060 Ships in 12 - 17 working days

This comprehensive Research Handbook reflects the latest research breakthroughs and practices in services management. Addressing services management from a broader strategic perspective, it delves into the key issues of analytics and service robots, and their potential impact. Edited by the late Mark M. Davis, it represents an early foray into the new frontier of services management and provides insights into the future of the field. Drawing together expert service researchers, the Research Handbook begins with an analysis of service strategy and operations management, before moving on to explore service innovation and design, serving customers, healthcare services and artificial intelligence in service. Chapters explore a wide range of topics including scarcity strategies, perceived justice in services, the role of culture and religion in service provision, and the implications of Covid-19 on healthcare service operations. The book concludes with a reflection on the fourth industrial revolution that is occurring now and the understanding of services in an era of advanced technologies. Addressing emerging challenges and opportunities, this Research Handbook will be critical reading for scholars and advanced students of services management and information systems. It will also be beneficial for practitioners and business managers in service industries.

Forensic Psychology - Crime, Justice, Law, Interventions (4th edition): Graham M. Davies, Anthony R. Beech, Melissa F Colloff Forensic Psychology - Crime, Justice, Law, Interventions (4th edition)
Graham M. Davies, Anthony R. Beech, Melissa F Colloff
R1,464 R1,377 Discovery Miles 13 770 Save R87 (6%) Ships in 12 - 17 working days

Complete introduction to forensic psychology and understanding psychology's expanding influence on the study of law, crime, and criminality Highlighting the often-sizable gap between media myths surrounding forensic practice and reality, Forensic Psychology presents a broad range of topics within the field, including detailed treatments of the causes of crime, investigative methods, the trial process, and interventions with different types of offenders and offenses. To aid in reader comprehension, this Fourth Edition is supplemented with additional online resource materials, including related links, multiple choice questions, and PowerPoint slides. Authored by a wide range of experienced forensic psychology professionals and drawing on a wealth of experience from leading researchers and practitioners, Forensic Psychology includes information on: Pyschological approaches to understanding crime and developmental and psychological theories of offending  Contributions of neuroscience in understanding risk factors for offending and effects of interpersonal crime on victims Eyewitness evidence, psychopathy, interviewing winesses and suspects, detecting deception, and offender profiling and crime linkage Interpersonal violence and stalking, judicial processes, safeguarding vulnerable witnesses, criminal responsibilities, and the role of the expert witness  Rehabilitation of offenders, risk assessment, treating dangerous offenders, and interventions with female offenders and offenders with intellectual disabilities With comprehensive coverage of the subject and its many important intricacies, the Fourth Edition of Forensic Psychology is essential reading for undergraduates' first encounter with the subject area and is also an excellent introduction for more specialized postgraduate courses.

An Authentic History of the Late War Between the United States and Great Britain - to Which Will Be Added, the War With Algiers... An Authentic History of the Late War Between the United States and Great Britain - to Which Will Be Added, the War With Algiers and the Treaty of Peace, the Treaties of Peace With the Various Tribes of North American Indians and the United States Army Regi (Paperback)
Paris M. Davis
R572 Discovery Miles 5 720 Ships in 12 - 17 working days
Universalism Unmasked - or the Spurious Gospel Exposed: Containing Those Lectures in Reply to Three by the Rev. John Percy, the... Universalism Unmasked - or the Spurious Gospel Exposed: Containing Those Lectures in Reply to Three by the Rev. John Percy, the Rev. S. W. Fuller, and Rev. A. C. Thomas: Also One Hundred Reasons Against the System of Universalism and an Exmination and Re (Paperback)
James M. Davis
R530 Discovery Miles 5 300 Ships in 12 - 17 working days
An Authentick History of the Late War Between the United States and Great Britain ... - to Which Will Be Added, the War With... An Authentick History of the Late War Between the United States and Great Britain ... - to Which Will Be Added, the War With Algiers, and the Treaty of Peace; the Treaties of Peace With the Various Tribes of North American Indians and the United States' Ar (Paperback)
Paris M. Davis
R571 Discovery Miles 5 710 Ships in 12 - 17 working days
Dreamcatcher (Paperback): Rachel M. Davis Dreamcatcher (Paperback)
Rachel M. Davis
R517 Discovery Miles 5 170 Ships in 12 - 17 working days

Having spent many years teaching and inspiring others, Rachel M Davis has fulfilled one of her ambitions as a professional musician, with the worldwide release of her first CD of moving and original solo piano music called 'Dreamcatcher'. Recorded on a Steinway piano under studio conditions Rachel has produced an incredibly beautiful sound. Working with a team of recording specialists, the production is truly world class and has been described as 'The type of music that makes you wish you kept up those piano lessons...' The CD and the book of sheet music will be of enormous interest to a broad section of classical and popular music lovers with a style reminiscent of Enya (Orinoco Flo) Andrew Lloyd-Webber (Phantom of the Opera), Einaudi, and John Barry(Dances with Wolves). You can listen to samples of all 10 tracks at www.rachelmdavis.co.uk where you can also find links to buy the CD and sheet music or download the tracks from digital music sites like iTunes or Amazon.

Large Print Color By Numbers For Kids Ages 8-12 - Color By Numbers Coloring Book For Kids Ages 8-12 (Paperback): Michelle M... Large Print Color By Numbers For Kids Ages 8-12 - Color By Numbers Coloring Book For Kids Ages 8-12 (Paperback)
Michelle M Davis Publishing
R203 Discovery Miles 2 030 Ships in 10 - 15 working days
How to Memorize Scripture for Life - From One Verse to Entire Books: Andrew M Davis How to Memorize Scripture for Life - From One Verse to Entire Books
Andrew M Davis
R239 R201 Discovery Miles 2 010 Save R38 (16%) Ships in 9 - 15 working days

Through his years of experience in extended Scripture memorization, Andrew M. Davis helps readers commit to studying God’s word so they may grow in holiness, resist temptation, and share the gospel with lost people.

Current Issues in Applied Memory Research (Paperback): Graham M. Davies, Daniel B. Wright Current Issues in Applied Memory Research (Paperback)
Graham M. Davies, Daniel B. Wright
R1,597 Discovery Miles 15 970 Ships in 12 - 17 working days

Research on applied memory is one of the most active, interesting and vibrant areas in experimental psychology today. This book provides descriptions of cutting-edge research and applies them to three key areas of contemporary investigation: education, the law and neuroscience. In the area of education, findings from the study of memory are described which could have a major impact on testing practice, revision techniques for examinations and teaching basic literacy and numeracy. In applications to the law, recent findings shed new light on the dynamics of child abuse investigations, the status of traumatic memories recovered after long delays and a further challenge for the eyewitness: change blindness. Finally, in neuroscience, contributions cover the frightening question of whether patients can remember incidents during surgical operations under anaesthetic, the unexpected impact of handedness and rapid eye movements on memory proficiency and the status of deja vu: mystical experience or memory error? These accounts of recent research on applied memory have been written by leading experts in the field from both Europe and America, with the non-specialist in mind. They will interest students who wish to extend their reading beyond core material in cognitive psychology, graduates on more specialised courses in education, forensics and neuropsychology, and all those who wish to enrich their knowledge of the contemporary frontiers of applied memory research.

Fatal Solution - How a Healthcare System Used Tragedy to Transform Itself and Redefine Just Culture (Paperback): Jan M. Davies,... Fatal Solution - How a Healthcare System Used Tragedy to Transform Itself and Redefine Just Culture (Paperback)
Jan M. Davies, MSc, MD, FRCPC, FRAeS, Carmella Steinke, RRT, BHS(RT), MPA, W. Ward Flemons, MD, FRCPC
R1,068 Discovery Miles 10 680 Ships in 9 - 15 working days

One box of chemicals mistaken for another. Ingredients intended to be life-sustaining are instead life-taking. Families in shock, healthcare providers reeling and fingers starting to point. A large healthcare system's reputation hangs in the balance while decisions need to be made, quickly. More questions than answers. People have to be held accountable - does this mean they get fired? Should the media and therefore the public be informed? What are family members and the providers involved feeling? When the dust settles, will remaining patients be more safe or less safe? In this provocative true story of tragedy, the authors recount the journey travelled and what was learned by, at the time, Canada's largest fully integrated health region. They weave this story together with the theory about why things fall apart and how to put them back together again. Building on the writings and wisdom of James Reason and other experts, the book explores new ways of thinking about Just Culture, and what this would mean for patients and family members, in addition to healthcare providers. With afterwords by two of the major players in this story, the authors make a compelling case that Just Culture is as much about fairness and healing as it is about supporting a safety culture.

The Secret Body - How the New Science of the Human Body Is Changing the Way We Live (Hardcover): Daniel M. Davis The Secret Body - How the New Science of the Human Body Is Changing the Way We Live (Hardcover)
Daniel M. Davis
R629 R514 Discovery Miles 5 140 Save R115 (18%) Ships in 9 - 15 working days

'A perfect blend of cutting-edge science and compelling storytelling. Daniel Davis has a rare knack for making complex science comprehensible and thrilling' BILL BRYSON Welcome to a revolution in the science of you. Recent and dramatic breakthroughs in our understanding of the body will profoundly change the experience of being human in the coming century. Already they are opening up boundary-breaking possibilities for intervention at every level, from our brains and genes to our microbiomes and immune systems. These will confer unprecedented powers over health, childhood development, our cognitive and physical abilities, and affect every aspect of how we live our lives and think about ourselves. As the secrets of our bodies are revealed, we all will face previously unthinkable choices with consequences we have yet to understand. Imagine knowing years in advance the precise likelihood of developing specific cancers, thanks to a bespoke understanding of every cell in your body; following a diet and health regime tailored to your microbiome; continuous monitoring of your body's workings and well-being; taking drugs that improve your cognition and help to acquire new skills; manipulating the genes of your unborn children to eliminate disease or even enhance their capabilities. Written by an award-winning scientist at the forefront of this work, The Secret Body shows how these radical and disconcerting possibilities have been made real thanks to the ingenious technologies and decades-long collaborations of scientists worldwide. A gripping drama of discovery and a landmark account of this dawning revolution, it presents a vision of the human body of dizzying complexity, wonder and possibility. 'A beautifully rendered picture of the startling new discoveries in human biology which are radically altering our understanding of how we function and what our future holds' BRIAN COX 'An extraordinary journey that reveals the magnificence, intricacy and beauty of the human body, fundamentally changing the way we see ourselves. Masterful' ALICE ROBERTS

Mind, Value, and Cosmos - On the Relational Nature of Ultimacy (Paperback): Andrew M Davis Mind, Value, and Cosmos - On the Relational Nature of Ultimacy (Paperback)
Andrew M Davis
R1,024 Discovery Miles 10 240 Ships in 12 - 17 working days

Mind, Value, and Cosmos: On the Relational Nature of Ultimacy is an investigation into the nature of ultimacy and explanation, particularly as it relates to the status of, and relationship among Mind, Value, and the Cosmos. It draws its stimulus from longstanding "axianoetic" convictions as to the ultimate status of Mind and Value in the western tradition of philosophical theology, and chiefly from the influential modern proposals of A.N. Whitehead, Keith Ward, and John Leslie. What emerges is a relational theory of ultimacy wherein Mind and Value, Possibility and Actuality, God and the World are revealed as "ultimate" only in virtue of their relationality. The ultimacy of relationality-what Whitehead calls "mutual immanence"-uniquely illuminates enduring mysteries surrounding: any and all existence, necessary divine existence, the nature of the possible, and the world as actual. As such, it casts fresh light upon the whence and why of God, the World, and their ultimate presuppositions.

Fatal Solution - How a Healthcare System Used Tragedy to Transform Itself and Redefine Just Culture (Hardcover): Jan M. Davies,... Fatal Solution - How a Healthcare System Used Tragedy to Transform Itself and Redefine Just Culture (Hardcover)
Jan M. Davies, MSc, MD, FRCPC, FRAeS, Carmella Steinke, RRT, BHS(RT), MPA, W. Ward Flemons, MD, FRCPC
R4,150 Discovery Miles 41 500 Ships in 12 - 17 working days

One box of chemicals mistaken for another. Ingredients intended to be life-sustaining are instead life-taking. Families in shock, healthcare providers reeling and fingers starting to point. A large healthcare system's reputation hangs in the balance while decisions need to be made, quickly. More questions than answers. People have to be held accountable - does this mean they get fired? Should the media and therefore the public be informed? What are family members and the providers involved feeling? When the dust settles, will remaining patients be more safe or less safe? In this provocative true story of tragedy, the authors recount the journey travelled and what was learned by, at the time, Canada's largest fully integrated health region. They weave this story together with the theory about why things fall apart and how to put them back together again. Building on the writings and wisdom of James Reason and other experts, the book explores new ways of thinking about Just Culture, and what this would mean for patients and family members, in addition to healthcare providers. With afterwords by two of the major players in this story, the authors make a compelling case that Just Culture is as much about fairness and healing as it is about supporting a safety culture.

Mind, Value, and Cosmos - On the Relational Nature of Ultimacy (Hardcover): Andrew M Davis Mind, Value, and Cosmos - On the Relational Nature of Ultimacy (Hardcover)
Andrew M Davis
R2,506 Discovery Miles 25 060 Ships in 12 - 17 working days

Mind, Value, and Cosmos: On the Relational Nature of Ultimacy is an investigation into the nature of ultimacy and explanation, particularly as it relates to the status of, and relationship between, Mind, Value, and the Cosmos. It draws its stimulus from longstanding "axianoetic" convictions as to the ultimate status of Mind and Value in the western tradition of philosophical theology, and chiefly from the influential modern proposals of A.N. Whitehead, Keith Ward, and John Leslie. What emerges is a relational theory of ultimacy wherein Mind and Value, Possibility and Actuality, God and the World are revealed as "ultimate" only in virtue of their relationality. The ultimacy of relationality-what Whitehead calls "mutual immanence"-uniquely illuminates enduring mysteries surrounding: any and all existence, necessary divine existence, the nature of the possible, and the world as actual. As such, it casts fresh light upon the whence and why of God, the World, and their ultimate presuppositions.

Handbook of Sexuality-Related Measures (Hardcover, 4th edition): Robin R. Milhausen, John K. Sakaluk, Terri D. Fisher, Clive M.... Handbook of Sexuality-Related Measures (Hardcover, 4th edition)
Robin R. Milhausen, John K. Sakaluk, Terri D. Fisher, Clive M. Davis, William L. Yarber
R6,526 Discovery Miles 65 260 Ships in 12 - 17 working days

This classic and invaluable reference handbook, written for sex researchers and their students, has now been completely revised in a new, fourth edition. It remains the only easy and efficient way for researchers to learn about, evaluate, and compare instruments that have previously been used in sex research.

The Power of Christian Contentment - Finding Deeper, Richer Christ-Centered Joy (Paperback): Andrew M Davis The Power of Christian Contentment - Finding Deeper, Richer Christ-Centered Joy (Paperback)
Andrew M Davis
R325 R268 Discovery Miles 2 680 Save R57 (18%) Ships in 4 - 8 working days

It may surprise modern Christians that our current problems with discontentedness are anything but new. In 1643, Puritan pastor Jeremiah Burroughs wrote a work titled "The Rare Jewel of Christian Contentment" that has as much resonance in our day as it did in his. Now pastor and author Andrew M. Davis helps contemporary Christians rediscover the remarkable truths found in this largely forgotten work. With powerful new illustrations and a keen sense of all that makes modern Christians restless, Davis challenges readers to confront the sources of discontent in their lives and embrace Paul's teaching on contentment in all circumstances. He gives special attention to maintaining contentment through poverty and prosperity, as well as in our marriages, and offers tips on teaching children how to be content in an age of smartphones and social media.

Turn Left at Orion - Hundreds of Night Sky Objects to See in a Home Telescope - and How to Find Them (Spiral bound, 5th Revised... Turn Left at Orion - Hundreds of Night Sky Objects to See in a Home Telescope - and How to Find Them (Spiral bound, 5th Revised edition)
Guy Consolmagno, Dan M. Davis
R893 Discovery Miles 8 930 Ships in 9 - 15 working days

With over 150,000 copies sold since its first publication, this is one of the most popular astronomy books of all time. This unique guidebook to the night sky shows you how to observe a host of celestial wonders. Its distinct format of object-by-object spreads illustrates how deep-sky objects and planets actually look through a small telescope, while its large pages and spiral binding allow for use outside. Along with updated star names and astronomical information, this new edition provides links to a dedicated webpage with up-to-date tables and images, and an improved planets chapter. The many Dobsonian-friendly images and small telescope views have been revised to account for changes in modern telescope technology, such as larger field of view eyepieces. With dedicated chapters on Northern and Southern Hemisphere objects, it's never been easier to explore the night sky, wherever you are. Additional resources are available on the accompanying website: www.cambridge.org/turnleft.

Crossing Borders - Essays on Literature, Culture, and Society in Honor of Amritjit Singh (Hardcover): Tapan Basu, Tasneem... Crossing Borders - Essays on Literature, Culture, and Society in Honor of Amritjit Singh (Hardcover)
Tapan Basu, Tasneem Shahnaaz; Contributions by Elleke Boehmer, Martha J Cutter, Thadious M. Davis, …
R3,189 Discovery Miles 31 890 Ships in 12 - 17 working days

Crossing Borders is a gathering of twenty original, interdisciplinary essays on the paradigm of borders in African American literature, multi-ethnic U.S. studies, and South Asian studies. These essays by established and mid-career scholars from around the globe employ a variety of approaches to the idea of "border crossings" and represent important contributions to the discourses on modernity, diasporic mobility, populism, migration, exile, sub-nation, trans-nation, as well as the formation of nationalities, communities, and identities. Borders, in these contexts, signify social and national inequities and hierarchies and also the ways to challenge and transgress entrenched barriers sanctioned by habit, custom, and law. The volume also honors and celebrates the life and work of Amritjit Singh as a teacher, mentor, author, scholar, and editor over half a century.

Feminism and Hospitality - Gender in the Host/Guest Relationship (Hardcover, New): Maurice Hamington Feminism and Hospitality - Gender in the Host/Guest Relationship (Hardcover, New)
Maurice Hamington; Contributions by Fauzia Erfan Ahmed, Patricia Boling, Stephanie Burdick-Shepherd, Jacqueline M. Davies, …
R3,184 Discovery Miles 31 840 Ships in 12 - 17 working days

Hospitality is something of a modern paradox. On the one hand, hospitality connotes a nicety or pleasantry easily undervalued as a ritual or formality devoid of epistemological or ethical content. On the other hand, the rise in international conflict and violence, the decline of civil speech, and the increased hostility toward immigrants points to the dire need for hospitable responses to mitigate tensions. Hospitality represents a further paradox for feminism. Historically, women have been saddled with disproportionate responsibility for hospitality and have also been treated as unwelcome guests in so many arenas. For these reasons, feminists have good reason to be wary of addressing hospitality. Yet, feminist theory has taken the lead on developing ontological, epistemological, and ethical approaches to connectedness and relationality such that addressing hospitality appears to be an appropriate extrapolation. Feminism and Hospitality is a collection that negotiates amidst these intriguing paradoxes. Feminism and Hospitality: Gender in the Host/Guest Relationship is the first collection of original works to bring a feminist analysis to issues and theories of personal, political, economic, and artistic hospitality. Furthermore, because feminist theorists have brought so much attention to the nature of human relationships, this volume employs a fresh analysis beyond the tradition in political theory.

Communication for Successful Aging - Empowering Individuals Across the Lifespan (Paperback): Howard Giles, Jessica Gasiorek,... Communication for Successful Aging - Empowering Individuals Across the Lifespan (Paperback)
Howard Giles, Jessica Gasiorek, Sharde M. Davis, Jane Giles
R1,458 Discovery Miles 14 580 Ships in 12 - 17 working days

This essential volume explores the vital role of communication in the aging process and how this varies for different social groups and cultural communities. It reveals how communication can empower people in the process of aging, and that how we communicate about age is critically important to - and is at the heart of - aging successfully. Giles et al. confront the uncertainty and negativity surrounding "aging" - a process with which we all have to cope - by expertly placing communication at the core of the process. They address the need to avoid negative language, discuss the lifespan as an evolving adventure, and introduce a new theory of successful aging - the communication ecology model of successful aging (CEMSA). They explore the research on key topics including: age stereotypes, age identities, and messages of ageism; the role of culture, gender, ethnicity, and being a member of marginalized groups; the ingredients of intergenerational communication; depiction of aging and youth in the media; and how and why talk about death and dying can be instrumental in promoting control over life's demands. Communication for Successful Aging is essential reading for graduate students of psychology, human development, gerontology, and communication, scholars in the social sciences, and all of us concerned with this complex academic and highly personal topic.

Communication for Successful Aging - Empowering Individuals Across the Lifespan (Hardcover): Howard Giles, Jessica Gasiorek,... Communication for Successful Aging - Empowering Individuals Across the Lifespan (Hardcover)
Howard Giles, Jessica Gasiorek, Sharde M. Davis, Jane Giles
R4,128 Discovery Miles 41 280 Ships in 12 - 17 working days

This essential volume explores the vital role of communication in the aging process and how this varies for different social groups and cultural communities. It reveals how communication can empower people in the process of aging, and that how we communicate about age is critically important to - and is at the heart of - aging successfully. Giles et al. confront the uncertainty and negativity surrounding "aging" - a process with which we all have to cope - by expertly placing communication at the core of the process. They address the need to avoid negative language, discuss the lifespan as an evolving adventure, and introduce a new theory of successful aging - the communication ecology model of successful aging (CEMSA). They explore the research on key topics including: age stereotypes, age identities, and messages of ageism; the role of culture, gender, ethnicity, and being a member of marginalized groups; the ingredients of intergenerational communication; depiction of aging and youth in the media; and how and why talk about death and dying can be instrumental in promoting control over life's demands. Communication for Successful Aging is essential reading for graduate students of psychology, human development, gerontology, and communication, scholars in the social sciences, and all of us concerned with this complex academic and highly personal topic.

Dreamscapes in Italian Cinema (Hardcover): Francesco Pascuzzi, Bryan Cracchiolo Dreamscapes in Italian Cinema (Hardcover)
Francesco Pascuzzi, Bryan Cracchiolo; Contributions by Axel Andersson, Eleanor Andrews, Linda Belau, …
R2,498 Discovery Miles 24 980 Ships in 12 - 17 working days

Dreamscapes in Italian Cinema explores different representations of dreams, visions, hallucinations, and hypnagogic states in Italian film culture, covering the works of some of the most significant auteurs in the history of Italian cinema (Fellini, Pasolini, Moretti, Bellocchio, among others). Dreams are discussed both in a filmic context, considering the diegetic and formal techniques employed to construct and represent them, and as allegories or metaphors in a broader cultural, political, and social sense (the film industry itself as the proverbial dream factory, and dreams as hopes, aspirations or altogether parallel universes, for example). The book covers works released over different decades and spanning multiple genres (drama, gothic film, horror, comedy), and it is intended to shed light on a topic that is as suggestive as it is insufficiently studied.

Patriotism, Democracy, and Common Sense - Restoring America's Promise at Home and Abroad (Paperback, New edition): Alan... Patriotism, Democracy, and Common Sense - Restoring America's Promise at Home and Abroad (Paperback, New edition)
Alan Curtis; Foreword by Kevin Phillips; Contributions by Eric Alterman, Phyllis A. Bennis, Sophie Body-Gendrot, …
R1,070 Discovery Miles 10 700 Ships in 12 - 17 working days

Featured on CNN, C-SPAN, FOX News, NBC's Today Show, Democracy NOW , News Hour with Jim Lehrer and other leading talk shows. In the late 1960s, the bipartisan Eisenhower Violence Commission, formed by President Lyndon Baines Johnson and extended by President Richard Nixon, warned that most civilizations have fallen less from external assault than from internal decay. Over recent years, the internal decay prophesied by the Violence Commission, but also by President Dwight D. Eisenhower in his military-industrial complex farewell speech, has been reflected in American public policies. The fault lies on both sides of the political aisle. After Pearl Harbor, "Mr. Republican," Senator Robert A. Taft, said criticism is patriotic. Patriotism, Democracy, and Common Sense assembles more than three dozen patriots. They range from Kevin Phillips, chief political strategist for Richard Nixon's victory in 1968, and former Ambassador Joseph Wilson IV, called a "true American hero" by President George H. W. Bush in 1991, to Jessica Tuchman Mathews, President of the Carnegie Endowment for International Peace, and former Oklahoma Senator Fred R. Harris, who advocated grassroots, populist policies when he ran for president in the 1970s. Why have American policies failed? What alternative policies can return America to its promise, internally and in the eyes of a global community shaken by, among other things, American torture and sexual humiliation of prisoners in Iraq? Patriotism, Democracy and Common Sense answers these questions in a preposterous way. It asks citizens and policy makers to actually connect the dots-to move America forward by developing mutually supportive and complementary foreign, national security, Middle East, economic, domestic, inner city, media, campaign finance and voting reform policies. Too much to expect of our civilization? This important and timely effort is published in cooperation with The Milton S. Eisenhower Foundation. From Patriotism, Democracy, and Common Se

Drug Design Strategies - Quantitative Approaches (Hardcover): David J. Livingstone, Andrew M Davis Drug Design Strategies - Quantitative Approaches (Hardcover)
David J. Livingstone, Andrew M Davis
R5,088 Discovery Miles 50 880 Ships in 12 - 17 working days

This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion (ie: numerical analysis to enable robust predictions to be made). Each chapter includes a brief review of the topic showing the historical development of quantitative approaches, a survey/summary of the current state-of-the-art, a selection of well chosen examples with some worked through and an appreciation of what problems remain to be overcome as well as an indication of how the field may develop. After an overview of quantitative approaches to drug design the book describes the development of concepts of "drug-like properties", of quantitative structure-activity relationships and molecular modelling, and in particular, structure-based design approaches to guide lead optimisation. How to manage and describe chemical structures, underpins all quantitative approaches to drug design and these are described in the following chapters. The next chapter covers the value of a quantitative approach, and also the challenge which is to describe the confidence in any prediction, and methods to assess predictive model quality. The later chapters describe the application of quantitative approaches to describing and optimising potency, selectivity, drug metabolism and pharmacokinetic properties and toxicology, and the design of chemical libraries to feed the screening approaches to lead generation that underpin modern drug discovery. Finally the book describes the impact of bioinformatics, current status of predicting ligand affinity direct from the protein structure, and the application of quantitative approaches to predicting environmental risk. The book provides a summary of the current state-of-the-art in quantitative approaches to drug design, and future opportunities, but it also provides inspiration to drug design practitioners to apply careful design, to make best use of the quantitative methods that are available, while continuing to improve them. Drug discovery still relies heavily on random screening and empirical screening cascades to identify leads and drugs and the process has many failures to deliver only a small handful of drugs. With the rapidly escalating costs of drug discovery and development together with spiralling delivery, quantitative approaches hold the promise of shifting the balance of success, to enable drug discovery to maintain its economic viability.

Revitalize - Biblical Keys to Helping Your Church Come Alive Again (Paperback): Andrew M Davis, Mark Dever Revitalize - Biblical Keys to Helping Your Church Come Alive Again (Paperback)
Andrew M Davis, Mark Dever
R467 Discovery Miles 4 670 Ships in 10 - 15 working days

Church health is measured by more than just numbers, but declining membership is often a key symptom of a church in crisis. The pastor of a dying church doesn't need to be told it is dying; he needs to find the way forward--and he needs hope. Author and pastor Andrew Davis offers readers the lessons he's learned in his own journey of leading church transformation, including - keeping Christ's ownership of the church central - being humble - choosing your battles wisely - empowering godly men to join in leadership - making prayer a priority - focusing on the Word - and more Church decline is not inevitable. Revitalize gives pastors the spiritual support they long for and the practical advice they need to turn their churches around and position them for greater health in the future.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Samsung EO-IA500BBEGWW Wired In-ear…
R299 R249 Discovery Miles 2 490
Loot
Nadine Gordimer Paperback  (2)
R398 R330 Discovery Miles 3 300
Lucky Define - Plastic 3 Head…
R390 Discovery Miles 3 900
Angelcare Nappy Bin Refills
R165 R145 Discovery Miles 1 450
Be A Triangle - How I Went From Being…
Lilly Singh Hardcover R400 R49 Discovery Miles 490
The Papery A5 WOW 2025 Diary - Butterfly
R349 R324 Discovery Miles 3 240
Grey's Anatomy - Season 17
Ellen Pompeo DVD R363 Discovery Miles 3 630
Tenet
John David Washington, Robert Pattinson, … DVD R53 Discovery Miles 530
Sudocrem Skin & Baby Care Barrier Cream…
R210 Discovery Miles 2 100
Marvel Spiderman Fibre-Tip Markers (Pack…
R57 Discovery Miles 570

 

Partners