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This monograph reviews information published since 1997 on the
group B coxsackieviruses (CVB), a large and important group of
human enteroviruses. The CVB were discovered in the mid-20th
century, during the search for other poliovirus types, and within a
very few years of this discovery, the CVB had been implicated as
causes of human myocarditis and pancreatitis. The study of the CVB
is still inextricably linked with the fate of their well-known
relatives, the polioviruses, for as poliovirus eradication proceeds
around the world, the CVB emerge more prominently as the
enteroviruses best suited for continuing studies in enteroviral
molecular biology as well as understanding the mechanisms
underlying enteroviral pathogenesis. This volume reviews and
presents modern views on the spectrum of CVB biologies, from
interaction of the virus with its receptor through replication,
speciation, and induction of disease.
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