Targeted proteomics is a technology for detecting proteins of interest with high sensitivity, quantitative accuracy, and reproducibility. The analysis of a pre-defined group of proteins provides precise, quantitative, and sensitive data to scientists and clinicians and can provide information on a subset of proteins important for their biological function. In this volume, a panel of high-profile contributors provides an overview of targeted proteomics in biomedical science. The book is focused on current state-of-the-art technology and applications, and it will be a valuable source of information for everyone working in this field. The first part of the book provides detailed examples of the application of targeted proteomics in biomarker discovery and pathogenesis. The second part is focused on the various tools used in targeted proteomics, including bioinformatics approaches, while the final section is dedicated to biobanks, a vital aspect of targeted proteomics. The book is highly recommended for anyone interested in proteomics, disease pathogenesis, clinical protein science, and biomarker discovery.

Sue Roaf is famed for her approach to design and her awareness of energy efficiency. Here she reveals the concepts, structures and techniques that lie behind the realization of her ideals. By using her own house as a case study, Roaf guides the reader through the ideas for energy-efficient design or 'eco-design'. Now in its fourth edition, the bestselling Ecohouse continues to be both a technical guide and an inspiration for thousands of architects, designers and eco-builders all over the world. Ecohouse provides design information about the latest low-impact materials and technologies, showcasing the newest and best 'green' solutions. Revised and updated, this edition also includes new case studies inspiring readers with more real-life examples of how to make an ecohouse work.

Sue Roaf is famed for her approach to design and her awareness of energy efficiency. Here she reveals the concepts, structures and techniques that lie behind the realization of her ideals. By using her own house as a case study, Roaf guides the reader through the ideas for energy-efficient design or 'eco-design'.

Now in its fourth edition, the bestselling Ecohouse continues to be both a technical guide and an inspiration for thousands of architects, designers and eco-builders all over the world.

Ecohouse provides design information about the latest low-impact materials and technologies, showcasing the newest and best green solutions. Revised and updated, this edition also includes new case studies inspiring readers with more real-life examples of how to make an ecohouse work.

Reflecting on the rapidly disintegrating course of events in Central Europe, this account centers on the lives of Transylvanian Count Balint Abady, his beloved Adrienne, and his flawed cousin Laszlo Gveroffy, who dies in poverty and neglect. Told with humor and bittersweet nostalgia, this book chronicles the sinister and fast-moving events in Montenegro, the Balkan Wars, and the apparent encirclement of Germany and Austria-Hungary by Britain, France, and Russia. This compelling novel deals with Hungarian politics on the verge of collapse and the assassination of Archduke Franz Ferdinand as the youth of Hungary march gaily off not only to their death on the battle field but also to the disintegration of their once-great country. "Reflexionando sobre el curso de desintegracion rapida de los acontecimientos en Europa central, este cuento se centra en la vida del conde transilvano Balint Abady, su amada Adriana y su primo "defectuoso "Laszlo Gveroffy, que muere en la pobreza y el abandono. Contado con humor y nostalgia agridulce, este libro narra los sucesos siniestros y vertiginosos en Montenegro, la guerra de los Balcanes y el cerco aparente de Alemania y Austria-Hungria por Gran Bretana, Francia y Rusia. Esta novela absorbente trata sobre la politica de Hungria al borde del colapso y el asesinato del archiduque Franz Ferdinand mientras los jovenes de Hungria marchan alegremente, no solamente a sus muertes en el campo de batalla, sino tambien a la desintegracion de su otrora gran pais."

Continuing the story of the two Transylvanian cousins from "They Were Counted, "this novel parallels the lives of the counts Balint Abady and Laszlo Gyeroffy to the political fate of their country: Balint has been forced to abandon the beautiful and unhappy Adrienne Miloth, while his cousin Laszlo continues down the path of self-destruction. Hungarian politicians continue with their partisan rivalries, meanwhile ignoring the needs of their fellow citizens. Obstinate in their struggle against Viennese sovereignty and in keeping their privileges, Hungarian politicians and aristocrats are blind to the fact that the world powers are nearing a conflict so large that it will soon give way to World War I and lead to the end of the world as they know it. "They Were Found Wanting "is the second novel of the Transylvanian Trilogy published by Miklos Banffy between 1934 and 1940, and it is considered one of the most important Central European narratives of the first half of the twentieth century. "Retomando la historia de los dos primos transilvanos que protagonizaban "Los dias contados," esta novela narra como las vidas de los condes Balint Abady y Laszlo Gyeroffy transcurren paralelas al destino politico de su pais: Balint se ha visto forzado a abandonar a la bella e infeliz Adrienne Miloth, mientras que su primo Laszlo persevera en su empeno autodestructivo. Entretanto, los politicos hungaros continuan con sus luchas partidistas despreciando las necesidades reales de sus conciudadanos. Obstinados en su pugna contra la soberania vienesa y en mantener sus privilegios, los politicos y aristocratas hungaros seran incapaces de ver como las grandes potencias se estan acercando peligrosamente a una conflagracion que mas tarde desembocara en la primera guerra mundial y terminara con el mundo tal como lo han conocido. "Las almas juzgadas" es la segunda novela de la Trilogia transilvana que Miklos Banffy publico entre 1934 y 1940, y esta considerada como una de las obras mas importantes de la narrativa centroeuropea de la primera mitad del siglo XX. "