The refreshed insights into early-imperial Roman historiography this book offers are linked to a recent discovery. In the spring of 2014, the binders of the archive of Robert Marichal were dusted off by the ERC funded project PLATINUM (ERC-StG 2014 n Degrees636983) in response to Tiziano Dorandi's recollections of a series of unpublished notes on Latin texts on papyrus. Among these was an in-progress edition of the Latin rolls from Herculaneum, together with Marichal's intuition that one of them had to be ascribed to a certain 'Annaeus Seneca'. PLATINUM followed the unpublished intuition by Robert Marichal as one path of investigation in its own research and work. Working on the Latin P.Herc. 1067 led to confirm Marichal's intuitions and to go beyond it: P.Herc. 1067 is the only extant direct witness to Seneca the Elder's Historiae. Bringing a new and important chapter of Latin literature arise out of a charred papyrus is significant. The present volume is made up of two complementary sections, each of which contains seven contributions. They are in close dialogue with each other, as looking at the same literary matter from several points of view yields undeniable advantages and represents an innovative and fruitful step in Latin literary criticism. These two sections express the two different but interlinked axes along which the contributions were developed. On one side, the focus is on the starting point of the debate, namely the discovery of the papyrus roll transmitting the Historiae of Seneca the Elder and how such a discovery can be integrated with prior knowledge about this historiographical work. On the other side, there is a broader view on early-imperial Roman historiography, to which the new perspectives opened by the rediscovery of Seneca the Elder's Historiae greatly contribute.

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

There have been extraordinary developments in the field of neuroscience in recent years, sparking a number of discussions within the legal field. This book studies the various interactions between neuroscience and the world of law, and explores how neuroscientific findings could affect some fundamental legal categories and how the law should be implemented in such cases. The book is divided into three main parts. Starting with a general overview of the convergence of neuroscience and law, the first part outlines the importance of their continuous interaction, the challenges that neuroscience poses for the concepts of free will and responsibility, and the peculiar characteristics of a "new" cognitive liberty. In turn, the second part addresses the phenomenon of cognitive and moral enhancement, as well as the uses of neurotechnology and their impacts on health, self-determination and the concept of being human. The third and last part investigates the use of neuroscientific findings in both criminal and civil cases, and seeks to determine whether they can provide valuable evidence and facilitate the assessment of personal responsibility, helping to resolve cases. The book is the result of an interdisciplinary dialogue involving jurists, philosophers, neuroscientists, forensic medicine specialists, and scholars in the humanities; further, it is intended for a broad readership interested in understanding the impacts of scientific and technological developments on people's lives and on our social systems.

Rediscovered Classics of Japanese Animation is the first academic work to examine World Masterpiece Theater (Sekai Meisaku Gekijô, 1969-2009), which popularized the practice of adapting foreign children's books into long-running animated series and laid the groundwork for powerhouses like Studio Ghibli. World Masterpiece Theater (Sekai Meisaku Gekijô, 1969-2009) is a TV staple created by the Japanese studio Nippon Animation, which popularized the practice of adapting foreign children's books into long-running animated series. Once generally dismissed by critics, the series is now frequently investigated as a key early work of legendary animators Isao Takahata and Hayao Miyazaki. In the first book-length examination of the series, Maria Chiara Olitini analyzes cultural significance of World Masterpiece Theater, and the ways in which the series pioneered the importance of children’s fiction for Japanese animation studios and laid the groundwork for powerhouses like Studio Ghibli. Adapting a novel for animation also means decoding (and re-coding) socio-cultural patterns embedded in a narrative. World Masterpiece Theater stands as a unique example of this linguistic, medial, and cultural hybridisation. Popular children’s classics such as Little Women, Peter Pan, and Anne of Green Gables became the starting point of a full-fledged negotiation process in which Japanese animators retold a whole range of narratives that have one basic formula in common: archetypal stories with an educational purpose. In particular, the series played a role in shaping the pop culture image of a young girl (shôjo). Examining the series through the lens of animation studies as well as adaptation studies, Olitini sheds new light on this long-neglected staple of Japanese animation history.

What does museum accessibility mean today? How can it generate impact in museums and in society itself? Where should we begin to take concrete action? Museum Accessibility by Design: A Systemic Approach to Organizational Change guides readers through the process of designing a museum accessibility strategy. Real world examples, tools, and resources foster implementation. This book offers a comprehensive exploration of museum accessibility, with an up-to-date and critical survey of the discipline; a detailed, step-by-step guide on how to set up a rigorous and effective process that promotes accessibility throughout the museum institution; tools and suggestions for rethinking accessibility and usability for a diverse range of museum visitors; international case studies and best practices; and, a full accessibility training course with activities and exercises aimed at fostering an accessible mindset within any institution. An engaging and accessible resource for university students, museum professionals and researchers, this book speaks to museum professionals of all types, from those just starting out to seasoned experts looking for a comprehensive, multi-faceted look at museum accessibility.

The book reports on advanced topics in the areas of wearable robotics research and practice. It focuses on new technologies, including neural interfaces, soft wearable robots, sensors and actuators technologies, and discusses important regulatory challenges, as well as clinical and ethical issues. Based on the 4th International Symposium on Wearable Robotics, WeRob2018, held October 16-20, 2018, in Pisa, Italy, the book addresses a large audience of academics and professionals working in government, industry, and medical centers, and end-users alike. It provides them with specialized information and with a source of inspiration for new ideas and collaborations. It discusses exemplary case studies highlighting practical challenges related to the implementation of wearable robots in a number of fields. One of the focus is on clinical applications, which was encouraged by the colocation of WeRob2018 with the International Conference on Neurorehabilitation, INCR2018. Additional topics include space applications and assistive technologies in the industry. The book merges together the engineering, medical, ethical and political perspectives, thus offering a multidisciplinary, timely snapshot of the field of wearable technologies.

What does museum accessibility mean today? How can it generate impact in museums and in society itself? Where should we begin to take concrete action? Museum Accessibility by Design: A Systemic Approach to Organizational Change guides readers through the process of designing a museum accessibility strategy. Real world examples, tools, and resources foster implementation. This book offers a comprehensive exploration of museum accessibility, with an up-to-date and critical survey of the discipline; a detailed, step-by-step guide on how to set up a rigorous and effective process that promotes accessibility throughout the museum institution; tools and suggestions for rethinking accessibility and usability for a diverse range of museum visitors; international case studies and best practices; and, a full accessibility training course with activities and exercises aimed at fostering an accessible mindset within any institution. An engaging and accessible resource for university students, museum professionals and researchers, this book speaks to museum professionals of all types, from those just starting out to seasoned experts looking for a comprehensive, multi-faceted look at museum accessibility.

In this engaging book, Maria Chiara D'Argenio delineates a turn in recent Latin American filmmaking towards inter/cultural feature films made by non-Indigenous directors. Aimed at a global audience, but played by Indigenous actors, these films tell Indigenous stories in Indigenous languages. Over the last two decades, a growing number of Latin American films have screened the Indigenous experience by combining the local and the global in a way that has proved appealing at international film festivals. Locating the films in composite webs of past and present traditions and forms, Indigenous Plots in Twenty-First Century Latin American Cinema examines the critical reflection offered by recent inter/cultural films and the socio-cultural impact, if any, they might have had. Through the analysis of a selection of films produced between 2006 and 2019, the book gauges the extent to which non-Indigenous directors who set out to engage critically with colonial legacies and imaginaries, as well as with contemporary Indigenous marginalization, succeed in addressing these concerns by 'unthinking' and 'undoing' Western centrism and coloniality. Drawing on a wide range of disciplines and considering the entire cinematic process - from pre-production to the films' production, circulation and critical reception - Indigenous Plots in Twenty-First Century Latin American Cinema makes the case for a holistic cultural criticism to explain the cultural and political work cinema does in specific historical contexts.

Voix et silence se considerent traditionnellement comme deux phenomenes opposes, s'excluant l'un l'autre. Les contributions contenues dans ce volume se proposent de depasser une telle conception, en se centrant non seulement sur la valeur et les fonctions que les deux concepts peuvent recouvrir, mais aussi sur la relation complexe qui existe entre eux en linguistique et en litterature. Outre les deux poles constitues par la voix et le silence, on peut reperer dans le domaine des langues romanes une grande variete de voix silencieuses ou de silences expressifs : la communication non verbale et son interaction avec le langage verbal, les differentes voix (plus ou moins silencieuses) donnant expression a ce qui ne peut pas etre dit, ou bien la representation graphique - et donc apparemment " muette " - d'un phenomene potentiellement acoustique. Le cri silencieux de Daphne, rendu visible dans la sculpture de Gian Lorenzo Bernini illustrant la couverture, est la manifestation figurative de cette rencontre oxymorique entre la voix et le silence.

Africa is one of the most dynamic continents. It will play a key role in the coming decades in relation to the growth of cities, and environmental conditions will be of primary importance. The structural lack of water and sanitation infrastructure affects the development of Africa's growing urban environments. This book questions the relation between the wide-ranging fields of water and the urban discipline in the Sub-Saharan African context. In particular, it focuses on Dar es Salaam (Tanzania), a city where rapid urbanisation and high annual growth have led to increasing water demand and strained the water and sanitation systems. It examines the spaces water produces, the actors promoting various choices and solutions, the impact of different applied technologies, and the diverse sanitary conditions, focusing on their significance in the shape of the built environment and the urban planning practices and theory. As water occupies and creates spaces, this work tries to establish a relation among the spaces and the structure of the city itself, using infrastructure in the shape of networks that cross the city and on-site systems such as boreholes and latrines, to be considered a hybrid and potentially resilient system.

There have been extraordinary developments in the field of neuroscience in recent years, sparking a number of discussions within the legal field. This book studies the various interactions between neuroscience and the world of law, and explores how neuroscientific findings could affect some fundamental legal categories and how the law should be implemented in such cases. The book is divided into three main parts. Starting with a general overview of the convergence of neuroscience and law, the first part outlines the importance of their continuous interaction, the challenges that neuroscience poses for the concepts of free will and responsibility, and the peculiar characteristics of a "new" cognitive liberty. In turn, the second part addresses the phenomenon of cognitive and moral enhancement, as well as the uses of neurotechnology and their impacts on health, self-determination and the concept of being human. The third and last part investigates the use of neuroscientific findings in both criminal and civil cases, and seeks to determine whether they can provide valuable evidence and facilitate the assessment of personal responsibility, helping to resolve cases. The book is the result of an interdisciplinary dialogue involving jurists, philosophers, neuroscientists, forensic medicine specialists, and scholars in the humanities; further, it is intended for a broad readership interested in understanding the impacts of scientific and technological developments on people's lives and on our social systems.

We would like to welcome you to the proceedings of the workshops held in c- junction with the 27th International Conference on Conceptual Modeling (ER 2008). While the ER main conference covers a wide spectrum of conceptual modeling research, increasingly complex real-world problems demand new p- spectives and activeresearchin new applications.The ER workshopsattempt to provideresearchers, students, andindustry professionalswitha forumto present and discuss emerging hot topics related to conceptual modeling. We received 13 excellent proposals for workshops to be held with ER 2008. We accepted the following seven based on peer reviews: 1. The Second International Workshop on Conceptual Modeling for Life S- ences Applications (CMLSA 2008), organized by Yi-Ping Phoebe Chen and Sven Hartmann. 2. The 5th International Workshopon Evolution and Change in Data Mana- ment (ECDM 2008), organized by Fabio Grandi. 3. The 4th International Workshop on Foundations and Practices of UML (FP-UML 2008), organized by Juan Trujillo and Andreas L. Opdahl. 4. The First International Workshop on Modeling Mobile Applications and Services (M2AS 2008), organized by Fernando Ferri, Patrizia Grifoni, and Maria Chiara Caschera. 5. The Second International Workshop on Requirements, Intentions and Goals in Conceptual Modeling (RIGiM 2008), organized by Colette Rolland, C- son Woo, and Camille Salinesi. 6. The Second International Workshop on Semantic and Conceptual Issues in Geographic Information Systems (SeCoGIS 2008), organized by Esteban Zim anyi and Christophe Claramunt. 7. The 5th International Workshop on Web Information Systems Modeling (WISM 2008), organized by Flavius Frasincar, Geert-Jan Houben, and Philippe Thiran."

Adopting a strategic approach to risk management can maximize competitiveness and profitability. Total Safety and Productivity approaches offer managers a set of methods and tools to apply a Total Safety Management (TSM) philosophy to achieve this. The capability to anticipate, assess and plan for risks associated with future operations is a critical success factor, for enterprises of all types and sizes. The ability to risk assess actual operations with an easy to apply, resilient methodology can offer significant benefits in terms of the capacity to improve safety and performance. This book describes approaches that can be used alone or jointly to improve safety management in any organization. The methods are based on academic best practice and have been developed by leading experts, but are presented here in a practical way for application in industry by non-experts. The book outlines a professional approach to risk and safety management, which requires goal setting, planning and the measurement of performance, and encourages a safety management system that is woven holistically into the fabric of an organization so that it becomes part of the culture, the way people do their jobs, and helps ensure that issues are correctly prioritized and managed as they emerge. This book is essential reading for professionals, at both expert and non-expert level, who are interested in applying the TSM philosophy within their organization.

In this engaging book, Maria Chiara D’Argenio delineates a turn in recent Latin American filmmaking towards inter/cultural feature films made by non-Indigenous directors. Aimed at a global audience, but played by Indigenous actors, these films tell Indigenous stories in Indigenous languages. Over the last two decades, a growing number of Latin American films have screened the Indigenous experience by combining the local and the global in a way that has proved appealing at international film festivals. Locating the films in composite webs of past and present traditions and forms, Indigenous Plots in Twenty-First Century Latin American Cinema examines the critical reflection offered by recent inter/cultural films and the socio-cultural impact, if any, they might have had. Through the analysis of a selection of films produced between 2006 and 2019, the book gauges the extent to which non-Indigenous directors who set out to engage critically with colonial legacies and imaginaries, as well as with contemporary Indigenous marginalization, succeed in addressing these concerns by ‘unthinking’ and ‘undoing’ Western centrism and coloniality. Drawing on a wide range of disciplines and considering the entire cinematic process – from pre-production to the films’ production, circulation and critical reception – Indigenous Plots in Twenty-First Century Latin American Cinema makes the case for a holistic cultural criticism to explain the cultural and political work cinema does in specific historical contexts.

Adopting a strategic approach to risk management can maximize competitiveness and profitability. Total Safety and Productivity approaches offer managers a set of methods and tools to apply a Total Safety Management (TSM) philosophy to achieve this. The capability to anticipate, assess and plan for risks associated with future operations is a critical success factor, for enterprises of all types and sizes. The ability to risk assess actual operations with an easy to apply, resilient methodology can offer significant benefits in terms of the capacity to improve safety and performance. This book describes approaches that can be used alone or jointly to improve safety management in any organization. The methods are based on academic best practice and have been developed by leading experts, but are presented here in a practical way for application in industry by non-experts. The book outlines a professional approach to risk and safety management, which requires goal setting, planning and the measurement of performance, and encourages a safety management system that is woven holistically into the fabric of an organization so that it becomes part of the culture, the way people do their jobs, and helps ensure that issues are correctly prioritized and managed as they emerge. This book is essential reading for professionals, at both expert and non-expert level, who are interested in applying the TSM philosophy within their organization.

This book constitutes the refereed proceedings of the 5th International Symposium on Human Mental Workload: Models and Applications, H-WORKLOAD 2021, held virtually in November 2021.The volume presents 9 revised full papers, which were carefully reviewed and selected from 16 submissions. The papers are organized in two topical sections on models and applications.

This book constitutes the refereed proceedings of the 4th International Symposium on Human Mental Workload: Models and Applications, H-WORKLOAD 2020, held in Granda, Spain*, in December 2020.The volume presents one keynote paper as well as 13 revised full papers, which were carefully reviewed and selected from 22 submissions. The papers are organized in two topical sections on models and applications. *The conference was held virtually due to the COVID-19 pandemic.

The book reports on advanced topics in the areas of wearable robotics research and practice. It focuses on new technologies, including neural interfaces, soft wearable robots, sensors and actuators technologies, and discusses important regulatory challenges, as well as clinical and ethical issues. Based on the 4th International Symposium on Wearable Robotics, WeRob2018, held October 16-20, 2018, in Pisa, Italy, the book addresses a large audience of academics and professionals working in government, industry, and medical centers, and end-users alike. It provides them with specialized information and with a source of inspiration for new ideas and collaborations. It discusses exemplary case studies highlighting practical challenges related to the implementation of wearable robots in a number of fields. One of the focus is on clinical applications, which was encouraged by the colocation of WeRob2018 with the International Conference on Neurorehabilitation, INCR2018. Additional topics include space applications and assistive technologies in the industry. The book merges together the engineering, medical, ethical and political perspectives, thus offering a multidisciplinary, timely snapshot of the field of wearable technologies.

This book constitutes the refereed proceedings of the Third International Symposium on Human Mental Workload: Models and Applications, H-WORKLOAD 2019, held in Rome, Italy, in November 2019.The volume presents one keynote paper as well as 14 revised full papers, which were carefully reviewed and selected from 32 submissions. The papers are organized in two topical sections on models and applications.

This book offers a clear, yet comprehensive overview of the role of robots in our society. It especially focuses on the interaction between humans and robots, and on the social and political aspects of the integration of robots with humans, in their everyday life, both in the private and working sphere alike. Based on the lessons held by the author at "Scuola di Politiche" (transl. School of Political Sciences), this self-contained book mainly addresses an educated, though not-specialist, audience.

Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.

Africa is one of the most dynamic continents. It will play a key role in the coming decades in relation to the growth of cities, and environmental conditions will be of primary importance. The structural lack of water and sanitation infrastructure affects the development of Africa's growing urban environments. This book questions the relation between the wide-ranging fields of water and the urban discipline in the Sub-Saharan African context. In particular, it focuses on Dar es Salaam (Tanzania), a city where rapid urbanisation and high annual growth have led to increasing water demand and strained the water and sanitation systems. It examines the spaces water produces, the actors promoting various choices and solutions, the impact of different applied technologies, and the diverse sanitary conditions, focusing on their significance in the shape of the built environment and the urban planning practices and theory. As water occupies and creates spaces, this work tries to establish a relation among the spaces and the structure of the city itself, using infrastructure in the shape of networks that cross the city and on-site systems such as boreholes and latrines, to be considered a hybrid and potentially resilient system.

"Coop", "Voiello", "Superga" nomi propri? nomi comuni? Come funzionano i nomi commerciali (o marchionimi) nella lingua, quali tratti presentano quando entrano nel discorso? Il volume rappresenta il primo ampio studio sistematico sul funzionamento dei nomi commerciali nell'italiano scritto. Il suo carattere innovativo risiede nell'impostazione sperimentale con cui indaga i marchionimi, scandagliando sintatticamente un vasto "corpus" di dati testuali appositamente elaborato. Prendendo ispirazione ideale dalla lezione di Saussure, i nomi commerciali sono processualmente descritti nei loro valori correlativi: non come entita ontologicamente predefinite, bensi come il risultato di rapporti sintagmatici e paradigmatici da cogliere metodologicamente nell'analisi delle proposizioni in cui tali nomi ricorrono. Ne emerge una visione radicalmente nuova del nome commerciale, scevra da luoghi comuni onomastici o categoriali, e in grado di gettare un fascio di luce, da una prospettiva inconsueta, anche sul problema millenario dei nomi propri.