This issue of Otolaryngologic Clinics of North America, Guest Edited by Drs. Ofer Jacobowitz and Maria V. Suurna, is devoted to Sleep Apnea. This issue is one of six selected each year by our series Consulting Editor, Sujana S. Chandrasekhar. Articles in this important issue include: The Goals of Sleep Apnea Treatment, Phenotypes of Obstructive Sleep Apnea, Sleep Apnea in Women, Living (or not) with Snoring, Drug-Induced Sleep Endoscopy, Sleep Studies Interpretation and Application, First in Line: The Nose, Oral Appliances, Positional Therapy for Sleep Apnea, Weight Loss - Surgical and Non-Surgical , Palatopharyngoplasty and Multilevel Surgery in the 21st Century, Getting to the Bottom of the Tongue, Implantable Neurostimulation, and Skeletal Surgery for Obstructive Sleep Apnea.