-- This new edition offers significant new information, regarding new technologies like CRISPR-Cas, new housing systems and management practices (including metabolic cages), a table on injection volumes and recommended needle sizes, info on new concepts such as pain assessment by facial expression, possible anesthetic reversal agents, and the potential impact of common procedures on animal welfare. The regulatory section has been entirely updated. The book is now more relevant to an international audience, addressing differing regulations across borders. -- With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. These researchers and their lab technicians need a handy, quick and up-to-date reference guide to inform them of best practice when working with these animals. -- Unlike existing books on laboratory mice, this book focuses not only on veterinary medicine but also offers detailed information regarding management and behavior of mice. It also offers a concise synopsis of material relevant to those working with, and caring for, laboratory mice, making for an easily-used reference.

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution's IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee. This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare's Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.

"The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents" is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well-illustrated reference won a 2012 PROSE Award for Best Single Volume Reference in Science from the Association of American Publishers. The book includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. With many expert contributors, this will be an extremely valuable publication for biomedical researchers, laboratory animal veterinarians and other professionals engaged in laboratory animal science.
2012 PROSE Award winner for Best Single Volume Reference in Science from the Association of American PublishersOne-stop resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and deguIncludes up-to-date, common experimental methodsOrganized by species for easy access during bench research

This second edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
* At least 50% new information than first edition
* Includes topics on rat genetics and genomics, occupational health, and experimental models
* The premier source of information on the laboratory rat

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.

Research Regulatory Compliance offers the latest information on regulations and compliance in the laboratory. With the increasing complexity of regulations and need for institutional infrastructure to deal with compliance of animal use issues, as well as a requirement surrounding human subjects, this publication provides reputable guidance and information. The book is extremely helpful as a resource for researchers, administrators, and technicians in the laboratory, and is also a great asset for faculty or new researchers coming in to the laboratory environment. It will help prepare users for the deluge of regulatory and compliance issues they will face while conducting their scientific programs. The book is edited and authored by known leaders in the field of compliance and regulations, and contains extensive research on the topics. It represents the new standard for information in every laboratory.

With laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting.

Now in full color, the second edition of this book illustrates management practices and technical procedures with numerous figures and tables. It includes updated tables on anesthetic agents, methods of euthanasia, recommended needle sizes, injection sites, approximate values for injection, and sedative and immobilization agents. Plastic comb-bound for convenient and frequent use, this guide also provides sources and suppliers of additional information on rabbits, feed, and sanitation supplies.

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher's education.

-- This new edition offers significant new information, regarding new technologies like CRISPR-Cas, new housing systems and management practices (including metabolic cages), a table on injection volumes and recommended needle sizes, info on new concepts such as pain assessment by facial expression, possible anesthetic reversal agents, and the potential impact of common procedures on animal welfare. The regulatory section has been entirely updated. The book is now more relevant to an international audience, addressing differing regulations across borders. -- With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. These researchers and their lab technicians need a handy, quick and up-to-date reference guide to inform them of best practice when working with these animals. -- Unlike existing books on laboratory mice, this book focuses not only on veterinary medicine but also offers detailed information regarding management and behavior of mice. It also offers a concise synopsis of material relevant to those working with, and caring for, laboratory mice, making for an easily-used reference.