This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer.? There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition.? Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.

The Routledge English Language Introductions series provides a one-stop resource for students of all areas of language and linguistic study. Assuming no prior knowledge of the subject, books in the series offer activities, study questions, sample analyses, commentaries and key readings - all in the same volume. Each book contains an introduction, development, exploration and extension section and includes real texts from a wide range of sources. An innovative 'two-dimensional' design enables easy and flexible use. A companion website will be launched to coincide with publication of the book. Language in Theory:*provides a comprehensive introduction to the conceptual frameworks which underpin the study of language *draws on a wide range of texts from recipes by Nigella Lawson to briefings by Donald Rumsfeld and writings by John Berger and Toni Morrison *provides classic readings by the key names in the field from Derrida and Foucault to Lakoff and Johnson. Written by experienced teachers and authors, this accessible textbook is an essential resource for all students of English language and literature as well as those with an interest in a variety of subjects from philosophy to cultural studies. The accompanying website can be found at http://www.routledge.com/textbooks/0415320488

The Routledge English Language Introductions series provides a one-stop resource for students of all areas of language and linguistic study. Assuming no prior knowledge of the subject, books in the series offer activities, study questions, sample analyses, commentaries and key readings - all in the same volume. Each book contains an introduction, development, exploration and extension section and includes real texts from a wide range of sources. An innovative 'two-dimensional' design enables easy and flexible use. A companion website will be launched to coincide with publication of the book. Language in Theory:*provides a comprehensive introduction to the conceptual frameworks which underpin the study of language *draws on a wide range of texts from recipes by Nigella Lawson to briefings by Donald Rumsfeld and writings by John Berger and Toni Morrison *provides classic readings by the key names in the field from Derrida and Foucault to Lakoff and Johnson. Written by experienced teachers and authors, this accessible textbook is an essential resource for all students of English language and literature as well as those with an interest in a variety of subjects from philosophy to cultural studies. The accompanying website can be found at http://www.routledge.com/textbooks/0415320488

This book will constitute an original intervention into longstanding but insistently relevant debates around the significance of notions of 'performativity' to the critical analysis of early modern drama. In particular, the book aims to: show how the investigation of performativity can enable readings of Shakespeare and Jonson that challenge the dominant methodological frameworks within which those plays have come to be read; demonstrate that the thought of performativity does not come to rest in the simplicity of method or instrumentality, and that it resists its own claim that language and action might be understood as unproblematically instrumental; demonstrate that this self-resistance occurs or takes place as a moment in the process of articulating the claims of the performative, and that this process is itself in an important sense dramatic.

In The sense of Early Modern writing, Mark Robson pursues the relation between the concept of the 'early modern' and modernity, tracing the complex interactions of post-Romantic, philosophical aesthetics and early modern rhetoric and poetics. The book therefore questions the status of what we now think of as literary texts in a period prior to the emergence of literature as a category. In this way, Robson argues for an attention to the classical notion of aisthesis, that is, for the crucial dimension of perception and response in reading and thinking -- and its rhetorical determination -- to be taken into account. Robson's theoretically-informed approach, drawing in particular on the work of Jacques Derrida and Paul de Man, fundamentally challenges the idea that critical theory is of little relevance in the reading of early modern texts. The sense of Early Modern writing includes readings of both familiar and unfamiliar texts by Shakespeare, Sidney, Jonson, Hester Pulter and others, and considers topics such as ears, eyes, tongues, hands and voices, in order to ask: How should we read early modern texts? The book will therefore be of interest to all students and researchers in early modern or Renaissance studies, as well as to those thinking through the theories and histories of literature, aesthetics and rhetoric. -- .

This book will constitute an original intervention into longstanding but insistently relevant debates around the significance of notions of performativity to the critical analysis of early modern drama.

In particular, the book aims to:

• show how the investigation of performativity can enable readings of Shakespeare and Jonson that challenge the dominant methodological frameworks within which those plays have come to be read;

• demonstrate that the thought of performativity does not come to rest in the simplicity of method or instrumentality, and that it resists its own claim that language and action might be understood as unproblematically instrumental;

• demonstrate that this self-resistance occurs or takes place as a moment in the process of articulating the claims of the performative, and that this process is itself in an important sense dramatic.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

Stephen Greenblatt is the most important exponent of 'new historicism', a dynamic critical movement which rejects the traditional reliance on individual canonical texts, exploring a multitude of other, more marginal works and voices. Questioning not just literary but social, political and cultural assumptions about knowledge and power, Greenblatt's work has had a huge impact on contemporary theory.

Mark Robson discusses ideas specific to particular works and explores the relation of Greenblatt's thought to new historicism as well as other modes of criticism including the key topics of:

• context
• cultural poetics
• power, subversion and containment
• thick description
• anecdotes.

Providing a starting point for readers new to this crucial theorist's sometimes complex texts, or support for those deepening their understanding of his work, this guidebook is ideal for students in the fields of literary, history, social and cultural studies.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

This two-part, eight-volume, reset edition draws together a range of sources from the early modern era through to the industrial age, to show the changes and continuities in responses to the social, political, legal and spiritual problems that self-murder posed.

Stephen Greenblatt is the most important exponent of 'new historicism', a dynamic critical movement which rejects the traditional reliance on individual canonical texts, exploring a multitude of other, more marginal works and voices. Questioning not just literary but social, political and cultural assumptions about knowledge and power, Greenblatt's work has had a huge impact on contemporary theory.

Mark Robson discusses ideas specific to particular works and explores the relation of Greenblatt's thought to new historicism as well as other modes of criticism including the key topics of:

• context
• cultural poetics
• power, subversion and containment
• thick description
• anecdotes.

Providing a starting point for readers new to this crucial theorist's sometimes complex texts, or support for those deepening their understanding of his work, this guidebook is ideal for students in the fields of literary, history, social and cultural studies.

Exam board: AQA; Pearson Edexcel; OCR Level: AS/A-level Subject: History First teaching: September 2015 First exams: Summer 2016 (AS); Summer 2017 (A-level) Put your trust in the textbook series that has given thousands of A-level History students deeper knowledge and better grades for over 30 years. Updated to meet the demands of today's A-level specifications, this new generation of Access to History titles includes accurate exam guidance based on examiners' reports, free online activity worksheets and contextual information that underpins students' understanding of the period. - Develop strong historical knowledge: in-depth analysis of each topic is both authoritative and accessible - Build historical skills and understanding: downloadable activity worksheets can be used independently by students or edited by teachers for classwork and homework - Learn, remember and connect important events and people: an introduction to the period, summary diagrams, timelines and links to additional online resources support lessons, revision and coursework - Achieve exam success: practical advice matched to the requirements of your A-level specification incorporates the lessons learnt from previous exams - Engage with sources, interpretations and the latest historical research: students will evaluate a rich collection of visual and written materials, plus key debates that examine the views of different historians

When US pilot Colonel Joseph Ryan (Frank Sinatra) is shot down and placed in a German POW camp, he is more concerned with his own survival than escape. The top-ranking officer in the camp, he is initially reviled by his fellow British and American prisoners, who nickname him 'Von Ryan'. However, Ryan eventually comes to lead them in a daring escape attempt, taking over from the commanding British officer (Trevor Howard) and the escapees face many hazards as they commandeer a train to make their way across Italy, closely followed by the Nazis.

Four dragonriders on a mission to save their world. Elian and his dawn dragon, Aurora, lead the search for the fourth and final orb. Pursued by night dragons and helped by a WWI airman, the four dragonriders are drawn into a huge aerial battle between all the dragon enclaves. The ultimate fate of dragonkind hangs by a thread. To restore order, a terrible price must be paid ...

Arthur Kennedy and Peggy Dow star in this Second World War drama. After being blinded by a German sniper in North Africa, US soldier Larry Nevins (Kennedy) is placed in a military hospital where he tries to adapt to his disability with help from his fellow wounded servicemen and his new friends Joe (James Edwards) and Judy (Dow). When he eventually returns home, Joe finds himself questioning long-held attitudes and whether he was right to abandon his new friends in an attempt to reclaim his old life.

Dragon's in Areth each have a single predestined rider and a single life mission, given to them by the Oracle. But this once all-powerful being is now fatally damaged and fading fast... Only the dragons and their riders can save it! Pell and his night dragon Shadow must find the dark orb to help save the Oracle, leader of all dragonkind. But Segun, a power-hungry tyrant, stands in their way. Pell must use his flying skills, bravery and resourcefulness to the limit, as Segun is determined to get the orb - even if it means killing the opposition...

This new title in the Theatre And series confronts the complex relationship between theatre and death. Taking the position that all humans need to 'live' with the reality of death, Mark Robson draws on a range of examples, from Greek theatre to contemporary practitioners, in order to testify to the potency of both theatre and death in contemporary culture. Striking and thought-provoking, this book is ideal for undergraduate and postgraduate students of theatre and performance, or English literature students with an interest in tragedy.