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Mycotoxins produced by molds are common contaminants of many
important crops, including wheat, corn, rice, and peanuts. Some
mycotoxins are found in fruits and vegetables. These contaminants
have a broad range of toxic effects, including carcinogenicity,
neurotoxicity, and reproductive and developmental toxicity. The
occurrence of mycotoxins in foods is an unavoidable worldwide
problem. About 80 countries have imposed regulatory limits to
minimize human and animal exposure to mycotoxins. Regulatory
limits, including international standards, have tremendous economic
impact and must be developed using science-based risk assessments.
The purpose of Mycotoxin Protocols is to provide the scientific and
technological basis for analytical methods for use in obtaining the
exposure data needed for risk assessments. Mycotoxin Protocols is
divided into four sections, which are interc- nected. The first
section: Chapters 1-5 describe the general techniques for mycotoxin
analysis with emphasis on the importance of method validation based
on statistical parameters; sampling procedures for collecting a
sample as representative as possible of a bulk lot; the isolation
of mycotoxins for use as analytical standards or for toxicological
studies; the evaluation of purity and preparation of standards; and
the detection and identification of impu- ties in isolated
mycotoxins. Sections 2-4: Chapters 6-19 describe the most current
chromatographic and immunochemical methods for studies on the major
mycotoxins.
Mycotoxins, from the Greek "mukes" referring to fungi or slime
molds and toxin from the Latin "toxicum" referencing a poison for
arrows, have earned their reputation for being potentially
deleterious to the health and well being of a consuming organism,
whether it be animal or human. Unfortunately, mycotoxins are a
ubiquitous factor in the natural life cycle of food producing
plants. As such, control of the potential impact of mycotoxins on
food safety relies heavily upon accurate analysis and surveys
followed by commodity segregation and restricted use or
decontamination through processing. The purpose of this book is to
provide the most comprehensive and current information on the topic
of mycotoxins and assuring food safety. Chapters represented in the
book reflect such diverse topics ranging from occurrence and
impact, analysis, reduction through processing and plant breeding,
toxicology and safety assessments to regulatory perspectives.
Authors represent a range of international perspectives.
Mycotoxins, from the Greek "mukes" referring to fungi or slime
molds and toxin from the Latin "toxicum" referencing a poison for
arrows, have earned their reputation for being potentially
deleterious to the health and well being of a consuming organism,
whether it be animal or human. Unfortunately, mycotoxins are a
ubiquitous factor in the natural life cycle of food producing
plants. As such, control of the potential impact of mycotoxins on
food safety relies heavily upon accurate analysis and surveys
followed by commodity segregation and restricted use or
decontamination through processing. The purpose of this book is to
provide the most comprehensive and current information on the topic
of mycotoxins and assuring food safety. Chapters represented in the
book reflect such diverse topics ranging from occurrence and
impact, analysis, reduction through processing and plant breeding,
toxicology and safety assessments to regulatory perspectives.
Authors represent a range of international perspectives.
Mycotoxins produced by molds are common contaminants of many
important crops, including wheat, corn, rice, and peanuts. Some
mycotoxins are found in fruits and vegetables. These contaminants
have a broad range of toxic effects, including carcinogenicity,
neurotoxicity, and reproductive and developmental toxicity. The
occurrence of mycotoxins in foods is an unavoidable worldwide
problem. About 80 countries have imposed regulatory limits to
minimize human and animal exposure to mycotoxins. Regulatory
limits, including international standards, have tremendous economic
impact and must be developed using science-based risk assessments.
The purpose of Mycotoxin Protocols is to provide the scientific and
technological basis for analytical methods for use in obtaining the
exposure data needed for risk assessments. Mycotoxin Protocols is
divided into four sections, which are interc- nected. The first
section: Chapters 1-5 describe the general techniques for mycotoxin
analysis with emphasis on the importance of method validation based
on statistical parameters; sampling procedures for collecting a
sample as representative as possible of a bulk lot; the isolation
of mycotoxins for use as analytical standards or for toxicological
studies; the evaluation of purity and preparation of standards; and
the detection and identification of impu- ties in isolated
mycotoxins. Sections 2-4: Chapters 6-19 describe the most current
chromatographic and immunochemical methods for studies on the major
mycotoxins.
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