Practical Biostatistics: A Step-by-Step Approach for Evidence-Based Medicine, Second Edition presents a complete resource of biostatistical knowledge meant for health sciences students, researchers and health care professionals. The book's content covers the investigator's hypothesis, collective health, observational studies, the biostatistics of intervention studies, clinical trials and additional concepts. Chapters are written in a didactic way, making them easier to comprehend by readers with little or no background on statistics. Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision-making using statistical analyses of scientific methods and outcomes to drive further experimentation and diagnosis. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or hands-on guide on how to effectively incorporate biostatistics in clinical trials and research projects.

This volume, which is part of the Comparative Public Law Treaties directed by prof. Giuseppe Franco Ferrari, offers the result of a reflection on the characteristics of the constitutional laws of East Asia. In the course of the work, in addition to a deepening of understanding of the legal models considered, investigations were carried out for internal comparison between the Eastern Asian legal systems, as well as for comparison with public legal systems belonging to other, mainly Western, legal traditions. The sectors of the jurisdictions that have been examined concern (a) the constitutional system, with a separate analysis of the legislative, executive and judicial bodies including constitutional justice (in the national experiences that contemplate it), (b) the forms of political-administrative decentralization, and (c) the catalogue of fundamental rights. In accordance with the prevalent trends in international literature on comparative legal methodology (as far as we are concerned, in the area of constitutional law), both diachronic and synchronic profiles of the national legal systems have been examined.

There is often a dichotomy between the academic approach to singing that voice students learn in the studio and what professional singers do on the operatic and concert stage. Great singers at the top of the performing profession achieve their place with much analysis and awareness of their technique, art, interpretation and stagecraft that goes far beyond academic study and develops over years of experience, exposure, and the occasional embarrassing error. Master Singers brings these insights to the student, teacher, and emerging professional singer, giving them many needed signs and signals along the road to achieving their own artistry and established career. Through interviews with some of today's most accomplished and renowned concert and operatic singers, including Stephanie Blythe, David Daniels, Joyce DiDonato, Denyce Graves, Thomas Hampson, Jonas Kaufmann, Simon Keenlyside, Ewa Podle, Master Singers provides vocalists making the transition from student to professional with indispensable advice on matters ranging from technique and its practical application for effective stage projection to the practicalities of the business of professional singing and maintaining a career to recommendations for vocal hygiene and longevity in singing. Rather than relying on a traditional one-singer-at-a-time structure, Donald George and Lucy Mauro distill answers to a range of essential, probing questions into a thematic approach, creating not a standard interview book but a true reference for emerging professional singers. An indispensable resource and reliable guide, Master Singers will find its place on the bookshelf of singers of this generation and the next.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Wireless Power Transfer for e-Mobility: Fundamentals and Design Guidelines for Wireless Charging of Electric Vehicles provides a comprehensive resource for researchers and engineers engaged in the development of automotive WPT systems. The book opens with an overview of wireless technologies for power transfer and their evolution over time, then focusing on the application of this technology to electric mobility highlighting its importance in terms of impact and perspectives on the development of sustainable transport and autonomous driving. Chapters discuss the fundamentals of electromagnetic field in WPT systems and the circuit modelling. In addition, they examine core current electric vehicle systems and present-day automotive WPT standards. Design techniques of magnetic couplers, including compensation networks are explored in-depth alongside power electronics techniques for automotive WPT systems. Both stationary and dynamic automotive WPT systems are rigorously assessed. Finally, the problems of electromagnetic compatibility and electromagnetic field safety are described with particular attention to shielding techniques for the mitigation of magnetic field emissions. Addressing essential knowledge from foundational to advanced levels, Wireless Power Transfer for e-Mobility provides practical guidance to engineers and researchers developing the future of electric mobility.

Instrumentation and Control Systems for Nuclear Power Plants provides the latest innovative research on the design of effective modern I&C systems for both existing and newly commissioned plants, along with information on system implementation. Editor Mauro Cappelli and his team of expert contributors cover fundamentals, explore the most advanced research in control systems technology, and tackle topics such as human-machine interface, control room redesign, human factors issues, and control modeling. The inclusion of codes and standards, inspection procedures and regulatory issues ensure that the reader can confidently design their own I&C systems and integrate them into existing nuclear sites and projects.

Psychopathy and Criminal Behavior: Current Trends and Challenges fills a gap in the market by covering new topics and angles not addressed in other literature. The book's authors approach the interaction of psychopathy with different types of crime, reflecting on comorbidity with other disorders, symptoms and emotional function. In addition to examining questions of prevention and treatment, they present new developments with solid theory and scientific evidence, also addressing forensic realities. This is a must-have guide for practitioners, students or anyone interested in psychopathy, criminal behavior and the various avenues of treatment.

Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part Two, Volume 33 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with sections in this new release covering Biomembranes of extracellular vesicles: The protein component, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular vesicles at single patient level for clinical research, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, The Potential of Extracellular Vesicles for Brain Repair, Nucleic acids cargo of extracellular vesicles: Analysis and physiological function, Propolis flavonoids and terpenes, and much more.

Biotechnological Strategies for the Treatment of Gluten Intolerance provides a comprehensive overview of a wide range of biotechnological approaches that will further research and upon implementation improve the quality of life of this population. Gluten intolerance is a heterogeneous condition with varying levels of sensitivity that have typically been treated with a gluten free diet, but this book provides new and exciting biotechnological approaches that affect diet as well as non-dietary approaches. The reference describes the varying levels of sensitivity and explores symptoms beyond the intestines for a complete overview of the spectrum of sensitivity. The impact of diversity of wheat species, gluten quality and the nutritional values of gluten free products are extensively discussed. This reference is perfect for researchers and clinicians that want to further treatment options for those suffering from gluten sensitivity.

Materials Kinetics: Transport and Rate Phenomena provides readers with a clear understanding of how physical-chemical principles are applied to fundamental kinetic processes. The book integrates advanced concepts with foundational knowledge and cutting-edge computational approaches, demonstrating how diffusion, morphological evolution, viscosity, relaxation and other kinetic phenomena can be applied to practical materials design problems across all classes of materials. The book starts with an overview of thermodynamics, discussing equilibrium, entropy, and irreversible processes. Subsequent chapters focus on analytical and numerical solutions of the diffusion equation, covering Fick's laws, multicomponent diffusion, numerical solutions, atomic models, and diffusion in crystals, polymers, glasses, and polycrystalline materials. Dislocation and interfacial motion, kinetics of phase separation, viscosity, and advanced nucleation theories are examined next, followed by detailed analyses of glass transition and relaxation behavior. The book concludes with a series of chapters covering molecular dynamics, energy landscapes, broken ergodicity, chemical reaction kinetics, thermal and electrical conductivities, Monte Carlo simulation techniques, and master equations.

Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part 1 Volume 32 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with this release presenting chapters written by an international board of authors. Topics in this new release include Amyloid ss-peptide interaction with GM1 containing model membrane, The Human EV Membranome, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular Vesicles: Single patient analysis for clinical applications, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, Standardization and reproducibility in EV research: the support of a Quality management system, and much more.

Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer’s disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes chapters on phytotherapy and flavonoids. This book is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out.