This is the first book to provide a comprehensive treatment of theories and applications in the rapidly expanding field of the crystallography of modular materials. Molecules are the natural modules from which molecular crystalline structures are built. Most inorganic structures, however, are infinite arrays of atoms and some kinds of surrogate modules, e.g. co-ordination polyhedra, are usually used to describe them. In recent years the attention has been focused on complex modules as the basis for a systematic description of polytypes and homologous/polysomatic series (modular structures). This representation is applied to the modelling of unknown structures and understanding nanoscale defects and intergrowths in materials. The Order/Disorder (OD) theory is fundamental to developing a systematic theory of polytypism, dealing with those structures based on both ordered and disordered stacking of one or more layers. Twinning at both unit-cell and micro-scale, together with disorder, causes many problems, "demons", for computer-based methods of crystal structure determination. This book develops the theory of twinning with the inclusion of worked examples, converting the "demons" into useful indicators for unravelling crystal structure. In spite of the increasing use of the concepts of modular crystallography for characterising, understanding and tailoring technological crystalline materials, this is the first book to offer a unified treatment of the results, which are spread across many different journals and original papers published over the last twenty years.

Interviews and first-hand accounts of an historic decision that affected the mental health profession-and American society and culture Through the personal accounts of those who were there, American Psychiatry and Homosexuality: An Oral History examines the 1973 decision by the American Psychiatric Association (APA) to remove homosexuality from its diagnostic and statistical manual of mental disorders (DSM). This unique book includes candid one-on-one interviews with key mental health professionals who played a role in the APA's decision, those who helped organize gay, lesbian, and bisexual psychiatrists after the decision, and others who have made significant contributions in this area within the mental health field. American Psychiatry and Homosexuality presents an insider's view of how homosexuality was removed from the DSM, the gradual organization of gay and lesbian psychiatrists within the APA, and the eventual formation of the APA-allied Association of Gay & Lesbian Psychiatrists (AGLP). The book profiles 17 individuals, both straight and gay, who made important contributions to organized psychiatry and the mental health needs of lesbian and gay patients, and illustrates the role that gay and lesbian psychiatrists would later play in the mental health field when they no longer had to hide their identities. Individuals profiled in American Psychiatry and Homosexuality include: Dr. John Fryer, who disguised his identity to speak before the APA's annual meeting in 1972 on the discrimination gay psychiatrists faced in their own profession Dr. Charles Silverstein, who saw the diagnosis of homosexuality as a means of social control Dr. Lawrence Hartmann, who helped reform the APA and later served as its President in 1991-92 Dr. Robert J. Campbell, who helped persuade the APA's Nomenclature Committee to hear scientific data presented by gay activists Dr. Judd Marmor, an early psychoanalytic critic of theories that pathologized homosexuality Dr. Robert Spitzer, who chaired the APA's Nomenclature Committee Dr. Frank Rundle, who helped organize the first meeting of what would become the APA Caucus of Gay, Lesbian and Bisexual Psychiatrists Dr. David Kessler, AGLP President from 1980-82 Dr. Nanette Gartrell, a pioneer of feminist issues within the APA Dr. Stuart Nichols, President of the AGLP in 1983-84 and a founding member of the Gay and Lesbian Psychiatrists of New York (GLPNY) Dr. Emery Hetrick, a founding member of both AGLP and GLPNY Dr. Bertram Schaffner, who was instrumental in providing group psychotherapy for physicians with AIDS Dr. Martha Kirkpatrick, a long-time leader in psychiatry and psychoanalysis, both as a woman and an "out" lesbian Dr. Richard Isay, the first openly gay psychoanalyst in the American Psychoanalytic Association Dr. Richard Pillard, best known for studying the incidence of homosexuality in families of twins Dr. Edward Hanin, former Speaker of the APA Assembly Dr. Ralph Roughton, the first openly gay Training and Supervising Psychoanalyst to be recognized within the American and International Psychoanalytic Associations American Psychiatry and Homosexuality presents the personal, behind-the-scenes accounts of a major historical event in psychiatry and medicine and of a decision that has affected society and culture ever since. This is an essential resource for mental health educators, supervisors, and professionals; historians; and LGBT readers in general.

The year 2006 marked the 150th anniversary of the birth of Sigmund Freud, the father of psychoanalysis. To commemorate this event, the Austrian government sponsored a number of academic and cultural events. Among these was a historic gathering of representatives of the four major United States psychoanalytic organizations: the American Academy of Psychoanalysis and Dynamic Psychiatry, the American Psychoanalytic Asociation, Division 39 of the American Psychological Association, and the American Association for Psychoanalysis on Clinical LSocial Work/NMCOP. The essays presented by speakers from these organizations at the Embassy of Austria in Washington, D.C., survey the tremendous and wide-ranging influence that Freud had on history, contemporary society, culture and the arts. The essays form the centerpiece of this book. Complementing these wide-ranging essays are literary works and remarkable photographs of Freud, his family, colleagues and patients which were also presented during the commemorative celebrations of Freud in the United States and Austria.

From the nation's leading experts in healthcare safety-the first comprehensive guide to delivering care that ensures the safety of patients and staff alike. One of the primary tenets among healthcare professionals is, "First, do no harm." Achieving this goal means ensuring the safety of both patient and caregiver. Every year in the United States alone, an estimated 4.8 million hospital patients suffer serious harm that is preventable. To address this industry-wide problem-and provide evidence-based solutions-a team of award-winning safety specialists from Press Ganey/Healthcare Performance Improvement have applied their decades of experience and research to the subject of patient and workforce safety. Their mission is to achieve zero harm in the healthcare industry, a lofty goal that some hospitals have already accomplished-which you can, too. Combining the latest advances in safety science, data technology, and high reliability solutions, this step-by-step guide shows you how to implement 6 simple principles in your workplace. 1. Commit to the goal of zero harm.2. Become more patient-centric.3. Recognize the interdependency of safety, quality, and patient-centricity.4. Adopt good data and analytics.5. Transform culture and leadership.6. Focus on accountability and execution. In Zero Harm, the world's leading safety experts share practical, day-to-day solutions that combine the latest tools and technologies in healthcare today with the best safety practices from high-risk, yet high-reliability industries, such as aviation, nuclear power, and the United States military. Using these field-tested methods, you can develop new leadership initiatives, educate workers on the universal skills that can save lives, organize and train safety action teams, implement reliability management systems, and create long-term, transformational change. You'll read case studies and success stories from your industry colleagues-and discover the most effective ways to utilize patient data, information sharing, and other up-to-the-minute technologies. It's a complete workplace-ready program that's proven to reduce preventable errors and produce measurable results-by putting the patient, and safety, first.

This is the first book to provide a comprehensive treatment of theories and applications in the rapidly expanding field of the crystallography of modular materials. Molecules are the natural modules from which molecular crystalline structures are built. Most inorganic structures, however, are infinite arrays of atoms and some kinds of surrogate modules, e.g. co-ordination polyhedra, are usually used to describe them. In recent years the attention has been focused on complex modules as the basis for a systematic description of polytypes and homologous/polysomatic series (modular structures). This representation is applied to the modelling of unknown structures and understanding nanoscale defects and intergrowths in materials. The Order/Disorder (OD) theory is fundamental to developing a systematic theory of polytypism, dealing with those structures based on both ordered and disordered stacking of one or more layers. Twinning at both unit-cell and micro-scale, together with disorder, causes many problems, "demons", for computer-based methods of crystal structure determination. This book develops the theory of twinning with the inclusion of worked examples, converting the "demons" into useful indicators for unravelling crystal structure. In spite of the increasing use of the concepts of modular crystallography for characterising, understanding and tailoring technological crystalline materials, this is the first book to offer a unified treatment of the results, which are spread across many different journals and original papers published over the last twenty years.

The construction and operation of buildings is responsible for 41 percent of all primary energy use and 48 percent of all carbon emissions, and the impact of the demolition and removal of an older building can greatly diminish the advantages of adding green technologies to new construction. In Building Reuse, Kathryn Rogers Merlino makes an impassioned case that truly sustainable design requires reusing and reimagining existing buildings. Additionally, Merlino calls for a more expansive view of preservation that goes beyond keeping only the most distinctive structures based on their historical and cultural significance to embrace the creative reuse of even unremarkable buildings for their environmental value. Building Reuse includes a compelling range of case studies-from a private home to an eighteen-story office building-all located in the Pacific Northwest, a region with a long history of sustainable design and urban growth policies that have made reuse projects feasible. Reusing existing buildings can be challenging to accomplish, but changing the way we think about environmentally conscious architecture has the potential to significantly reduce energy consumption, carbon emissions, and waste.

Lean Behavioral Health: The Kings County Hospital Story is the first lean book that focuses entirely on behavioral health. Using the principles of the Toyota Production System, or lean, the contributors in this groundbreaking volume share their experience in transforming a major safety net public hospital after a tragic and internationally publicized event. As the largest public healthcare system in the United States, the New York City Health & Hospitals Corporation adopted lean as the transformational approach for all of its hospitals and clinics. Kings County Hospital Center, one of the largest providers of behavioral health care in the country, continues on its transformational journey utilizing lean's techniques. While not every event was fully successful, most were and every event, including failures, increased the knowledge base about how to continually improve quality and safety. Having made major changes, Kings County Hospital Center is now recognized as a center for transformation and quality receiving high marks from oversight agencies. This volume begins by describing the basic principles of the lean approach-adding value, eliminating waste, and tapping the organization's line staff to create and sustain dramatic change. An overview of the use of lean from a quality improvement perspective follows. Lean tools are applied to many services that comprise the behavioral health value stream and these stories are highlighted. The experts in identifying waste and adding value are the line staff whose voices are captured in the clinical chapters. Insights learned by event participants are emphasized as teaching points to provide context for what has worked or has not worked at Kings County Hospital Center. While the burning platform at Kings County Hospital Center was white hot and while the Department of Justice scrutinized its quality of patient care, the application of lean methods and tools has transformed the hospital into a potential model for behavioral health programs facing the challenges of the present healthcare environment. It is a must-have story for clinicians, administrators and other leaders in the mental health field devoted to improving quality and safety at their hospitals and clinics.

Gamma-Glutamyl Transpeptidases ( -GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the -glutamyl amide bond of glutathione to liberate cysteinylglycine. The released -glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). -GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxidant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis. -GT is upregulated during inflammation and in several human tumors, and it is involved in many physiological disorders related to oxidative stress, such as Parkinson's disease and diabetes. Furthermore, this enzyme is used as a marker of liver disease and cancer. This book covers current knowledge about the structure-function relationship of -GTs and gives information about applications of -GTs in different fields ranging from clinical biochemistry to biotechnology and biomedicine.