Using the clinical picture of triplet repeat disorders as a starting point, this work reviews and integrates understanding of the molecular pathologies, the genotype-phenotype relationships, and the mutational processes of trinucleotide repeats of triplet repeat disorders. Laboratory and clinical issues relating to genetic testing for these disorders are also addressed. This book is aimed at clinicians and researchers in genetics, neuroscience, paediatrics and psychiatry.

In 1614 the French Estates General met for the last time before the Revolution of 1789. The meeting marks the beginning of the political career of Cardinal Richelieu and provides an opportunity for studying the regency of Marie de Medicis. In another sense 1614 marks the end of the Estates General in its early modern form of three separate estates preparing lists of grievances from the preliminary lists submitted to each deputy by his electors, while attending to the needs of the king. This book provides a full description of that last meeting in 1614, based on extensive research into political pamphlets, diplomatic correspondence, records of the royal councils, local and national cahiers and the proces-verbaux of the meetings. The author sets the period in the wider context of the history of France from 1598 to 1616, with particular attention to economic conditions and international relations.

This book is the result of a life-time of interest in the Crosiers and presents the history in England and France of this religious Order, known officially as the Canons Regular of the Order of the Holy Cross. The core of the book is two chapters presenting the history of the Crosier in England (there called the Crutched Friars) and and in France (there known as the Croisiers). A first chapter discuses the origin and early years of the Crosier Order, its place among other orders of the Holy Cross and its spirituality. Then after the core of the book, the Afterword begins with a very short history of the Crosiers from the French Revolution to Vatican II. This is followed by a partial history of the Crosiers from Vatican II to the present, concentrating on the history of the Crosier Order in the United States. The third part presents a series of reflections on chapters one through three. The final part of the Afterword contains reflections on the present state of the Crosiers in light of its past.