The primary goal of this fascicle is to be a practical reference for pathologists who review liver biopsies, a most challenging area of diagnostic surgical pathology. It is focused on diagnostic histopathology, discussing and lavishly illustrating disease patterns with an emphasis on differential diagnosis. The key aspects of clinical features, laboratory findings, and pathophysiology are woven into this book. The application and interpretation of special stains and immunohistochemistry are integrated into discussions of each disease pattern.

Part of the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Liver, 4th Edition, provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the liver. Practical, well-organized, and highly readable, this fully revised volume by Dr. Michael S. Torbenson addresses both common and unusual issues that arise in the day-to-day interpretation of liver biopsies, teaching the best diagnostic practices as well as how to avoid the most common pitfalls. Frames each diagnosis in its most common clinical context, explaining how the pathology can be used to make key clinical management decisions. Presents key differential features of tumors, organized according to diagnostic category Features high-quality photomicrographs and illustrations throughout, including updated images both in print (over 700) and online-more than 900 images in all. Includes two new chapters on Radiology Report Interpretation and Cytogenetics and Genomics. Provides access to more than 100 questions and answers online for self-assessment and review. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,

Numerous advances in our understanding of the pathology and molecular features of liver tumors have been made since the publication of the previous series, nearly two decades ago. Examples of recent advances include the identification of novel entities, including their precursor lesions, the discovery of key molecular changes, including the fusion transcript between the DNAJB1 gene and the PRKACA gene in fibrolamellar carcinoma, the use of glutamine synthetase in the diagnosis of focal nodular hyperplasia, and the subtyping of hepatocellular adenomas using molecular and immunohistochemical methods. Together with the more unified classification and terminology of intrahepatic bile duct tumors and their precursors, these advances call for updated information that is presented in this volume.