Nanogels are three-dimensional nanosized networks that are formed by physically or chemically cross-linking polymers. They have been explored as a drug-delivery system due to their biocompatibility, high stability, particle-size adjustment, drug-loading capability and modification of the surface for active targeting by cognate receptors on the target cells of tissues. Nanogels can respond to stimuli such as pH, temperature, light and redox, which results in the controlled release of drugs and targeting of site by environmental stimuli and prevents accumulation in non-target tissues, minimizing the side effects of the drug. This book aims to provide a general introduction to nanogels and the design of various stimuli-sensitive nanogels that can control drug release in response to specific stimuli.

Gene therapy as a potential method for treatment of genetic disorders and other malignancies as well as treatment of many cancers has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene delivery systems, including controlled release. Smart nanostructures have been considered as a promising approach when applied to drug and gene delivery systems, and could solve the problems related to the inefficient transfer of medication to the affected cells.

Gene therapy as a potential method for the treatment of genetic disorders and other malignancies, as well as the treatment of many cancers, has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene-delivery systems, including controlled release. Nanoparticle (NP)-Based Delivery Vehicles looks at smart nanostructures and how these are considered a promising approach when applied to drug- and gene-delivery systems, in addition to how to solve the problems related to the inefficient transfer of medication to the affected cells.

This book provides a general introduction to nanogels, and designs of various stimuli-sensitive nanogels that are able to control drug release in response to specific stimuli. Nanogels are three-dimensional nanosized networks that formed by physically or chemically crosslinking polymers. They have highly interesting properties such as biocompatibility, high stability, particle size adjustment, drug loading capability and modification of the surface for active targeting. They can respond to stimuli which results in the controlled release of drug and targeting of the site.

This book provides a general introduction to nanogels, and designs of various stimuli-sensitive nanogels that are able to control drug release in response to specific stimuli. Nanogels are three-dimensional nanosized networks that formed by physically or chemically crosslinking polymers. They have highly interesting properties such as biocompatibility, high stability, particle size adjustment, drug loading capability and modification of the surface for active targeting. They can respond to stimuli which results in the controlled release of drug and targeting of the site.

Gene therapy as a potential method for treatment of genetic disorders and other malignancies as well as treatment of many cancers has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene delivery systems, including controlled release. Smart nanostructures have been considered as a promising approach when applied to drug and gene delivery systems, and could solve the problems related to the inefficient transfer of medication to the affected cells.