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The Active Pharmaceutical Ingredients (API) is functional
ingredients of a drug that acts against diseases. In other words,
the active ingredient(s) in a drug or medicine are the substances
that produce intended pharmacologic effects which might be positive
or negative. The quality and safety of the drugs depends on API and
new chemical entity development entirely depends on it. Most of the
pharmaceutical industries buy API from other manufacturing units.
Therefore, it becomes mandatory to check quality of APIs and other
raw materials. In the present study, assessment of the level of
APIs in local drugs and microbial quality of water used in
Pakistani pharmaceutics were studied. The present study found that
twelve (n=12) drugs being analyzed for their APIs concentration
were within acceptable level. These drugs include mefenamic acid,
pyrental pamoate, lignocaine hydrochlorid, ephedrine hydrochloride,
cimetidine, aspirin, metronidazole, salbutamol, sulphamethoxazole,
trimethoprim, benzyl benzoate and dexamethasone.The obtained
results were statistical different for different drugs (P 0.05).
However, no significant differences were found within drugs
groups."
Apolipoproteins B/A1 are protein components of antherogenic and non
antherogenicparticles. At the moment, measurement of LDL and HDL in
various combinations is in practice for diagnosis of
atherosclerotic CAD. But studies have proved that measurement of
their protein components is much better, cost effective, error free
and standardize. the current cross sectional analytical study has
confirmed that Apo B/A1 ratio is much better biochemical indicator
and people with obesity, high hip to waist ratio and other known
risk factors for CAD can be better identified for future risk of
CAD by measuring their Apo B/A1 ratio specially in men, however
value 1.8 rather than 0.9 can be more useful. Therefore all old age
men with known risk factor must immediately be monitored and given
lipid lowering drugs for prevention of developing CAD.
The story in this book is about a biologically potent new ligand
monobutylphthalate which has been synthesized by the ring opening
reaction of phthalic anhydride with butanol using dean stalk trap.
Eight transition metal complexes have been synthesized from this
novel ligand in 1:1 and 2:1 stoichiometry. The geometry of the
resulting complexes was proposed through IR spectroscopy. Ligand
and complexes were than subjected to various bacteria and fungi in
order to establish their biological activity. Results reveal that
the ligand and complexes exhibit significant to promising activity
against all type of bacteria and fungi. This monograph is equally
beneficial for both beginners and also ideal for experts
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Come Boldly
C. S. Lewis
Hardcover
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R195
Discovery Miles 1 950
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