This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

Drawing on modern business examples throughout, 'Change' is a pragmatic overview of change management for today's decision maker. It outlines key techniques for the whole change process, from understanding the catalysts for change to overcoming resistance.

Creativity in the face of both adversity and opportunity is the hallmark of career success. The premise of this book is that careers and creativity are broadly connected, both at the level of the individual and at the level of the larger institutions of work and society. Careers are both creative endeavours themselves, and introduce creativity into the wider employment system. By exploring models of creativity and career, and linking them with examples from a diverse array of professions, countries, and industries, this volume provides an in-depth look at contemporary careers.

How does one combine a challenging career with creativity? This book answers that question. Career Creativity explores different models of careers and creativity and the necessity for it. It is broken into four sections of study; 'Creative Careers Observed', 'Creative Careers Enacted', Careers in Creative Industries' and 'Careers Creating Industries'. This volume links these two ideals with key examples from various professions, countries and industries.

More than any other branch of organic chemistry, synthesis has improved our understanding of the structure, dynamics, and transition of molecules. The availability of sophisticated tools and new techniques has made organic synthesis more challenging than ever for those in the field. This updated edition of the 1970 work highlights significant and intriguing synthetic achievements: their ingenuity in design, extent of stereochemical control, new reactions, and new reagents. Approximately 100 examples illustrate various aspects of organic synthesis, with particular emphasis on bond-making and bond-breaking, dissymetry, conformation, and stereoelectric considerations. Each describes the synthesis of a natural product or of an unusual or strained molecule. Numerous flow sheets and perspective structural formulas illustrate the force of arguments predicting the stereochemical outcome of important steps. Also included is a type-transformation index which highlights some less common reactions.