|
Showing 1 - 7 of
7 matches in All Departments
The research work contains standardization, Development and
pharmacological evaluation of both Marketed syrup(Ayurlab's Herbal
Cough Syrup) and Developed syrup. In standardisation organoleptic,
physicochemical, physical and phytochemical evauation were
included. Also Heavy metal and Microbial analysis and Anti oxidant
activity were done. In Development water extracts of each
ingredients were prepared by spray dried method(Labultima) and hot
plate method. HPTLC evaluation were done by marker compounds and
fingerprinting done by comparing Rf value for particular
ingredient. By HPTLC evaluation it was conclude that extracts used
in preparation of syrup were genuie. It contains tables that gives
easy evaluation of data, figures which gives easy visulation in 254
and 366nm. It also contains 3D image and chromatogram. In
pharmacological evaluation animal activity done was antitussive
activity of Herbal Cough Syrup and Developed Syrup in sulphur
dioxide induced cough model using mice and anti inflammatory
activity of Herbal Cough Syrup and Developed Syrup in carragenan
induced rat paw oedema model and statical analysis was done using
Grapgpad Prism 5 software.
Mucoadhesive drug delivery system which utilize properties of
bioadhesion of certain water-soluble polymers which become adhesive
on hydration and hence can be used for targeting a drug to a
particular region of the body for extended period of time. The
mucosal layer lie a number of regions of the body including the
GIT, the urogenital tract, the airways, the ear, nose, mouth and
eye. The oral mucosal sites differ greatly from the one another in
terms of anatomy, permeability to an applied drug and their ability
to retain a delivery system for a desired length of time. The
Buccal and sublingual mucosal is relatively, permeable, giving
rapid absorption and acceptable bioavailability of drugs and is
convenient, easily accessible and generally well accepted
Stanazolol is a steroidal class drug. Stanazolol is a synthetic
anabolic steroid with therapeutic uses in treating c1-inhibitor
deficient hereditary Angioedema. Our main objective is to
Development and Validation of Simple UV-Spectroscopic Method for
stanazolol in bulk and Pharmaceutical dosage Form and development
and Validation of RP-HPLC methods for estimation of Stanazolol in
Bulk and Pharmaceutical dosage Form. Comparison of Developed and
Validated RP-HPLC Method against the developed and Validated Simple
Uv-Spectrophotometric Method. development of force degradation
method for detection of possible impurity of Stanazolol in API and
pharmaceutical dosage form.
A Honey Based Cough Syrup is a best selling product of Ayurlab
Herbals Pvt. Ltd., Halol, Gujarat, India. This book contain
introduction on standardization, cough and inflammation; review of
literature, standardization parameters, HPTLC estimation and
fingerprinting on Vasaka, Kantakari, Tulsi, Ginger, Mari,
Pipplimool, Twak, Tamalpatra, Baheda, Liquorice, Kankol mirch,
Banafsha and Brihat ela. Antitussive activity, antiinflammatory
activity and antioxidant activity of Honey Based Cough Syrup and
Compared with Developed Syrup.
The oral administration is the most convenient and commonly used
method for drug delivery. Traditionally, solid oral dosage forms
have been designed to release their drug load in the upper region
of the gastrointestinal tract, where conditions are more suited to
drug dissolutions and absorptions. Recently, greater emphasis has
been placed on controlling site of drug release from oral
formulations for the purposes of improving patient compliance and
treatment efficiency . Many protein and peptide drugs like insulin
cannot be administered through the oral route because of their
degradation by the digestive enzymes of the stomach and the small
intestine. Colon-specific drug delivery systems offer several
potential therapeutic advantages.The opportunity to reduce adverse
effects in the treatment of colonic diseases like, ulcerative
colitis, colorectal cancer, Chorn's diseases and amoebiasis by
topical application of drugs, active at the mucosal level The
elucidation of the mode of action of some nonsteroidal
anti-inflammatory drugs (NSAIDs) such as sulindac (metabolized in
the colon to the active moiety, sulindac sulfide) that were found
to interfere with the proliferation of co
The book provides an easy and up-to-date account of divergent vital
topic in a simple, lucid and concise manner. The text of the book
has been illustrated with simplified, well-labelled coloured
diagrams and relevent pictures to make the sbject easy to
understand and interesting to read for the students. Highlights Of
The Book: - Exhaustive subject matter well supported with the
relevant coloured photographs. - Contains standardization data of
each ingredient of poly herbal formulation. - Also contains reviews
of each ingredient. - Coloured photographs of HPTLC. - Comparative
studies of in vitro acid neutralizing capacity with allopathic
formulation.
Herbal medicines are in great demand in the developed as well as
developing countries for primary healthcare because of their
biological activities, higher safety margin and lesser cost. They
are number of medicinal plants in Ayurveda which required extusive
study. The qualities of herbs depend on various factors, hence it
is essential to establish herbal monograph and standardize the
herbal drug. The plants selected for establishment of herbal
monograph were based on its availability and its various
therapeutic activities in various ailments mentioned in Ayurveda.
Our objective of the research work was to establish herbal
monograph based on pharmacognostic, phytochemicals and
pharmacological parameters. This publication is most timely. I
believe this comprehensive text book will be of use and great value
to the students, academicians, researchers, teachers and herbal
drug industry.
|
|