Yukichi Fukuzawa was one of the most effective business entrepreneurs in early modern Japan. He was the inspiration for the Yokohama Specie Bank, without which the Japanese could not have set up a sound banking system. He began the bookstore chain Maruzen. He was adviser to the newly founded shipbuilding and mining giant Mitsubishi and helped bring the house of Mitsui into the modern age. This is both the story of his life and his transforming impact on Japan's economy.

The international symposium "Syringomyelia 2000" in Kobe, Japan, brought together experts in neurosurgery, neurology, and neuropathology. The decade leading up to this event saw remarkable developments in surgery and imaging technology. The symposium was thus an opportunity for researchers and clinicians to enhance and broaden the scope of their knowledge and to become more aware of work being done in complementary fields. With its collection of papers presented at the Kobe conference, this volume contains a thorough and comprehensive description of syringomyelia - its classification, pathology, and pathophysiology; experimental studies; and its association with abnormalities of the craniocervical junction, Chari II malformation, tethered cord, and other disorders. This compilation provides valuable state-of-the-art information for professionals in the fields of neurosurgery, neurology, and neuropathology and for all others concerned with syringomelia.

Surgical skill and imaging technology in the field of neurosurgery have developed remarkably during the past decade. Magnetic resonance imaging (MRI), with high contrast resolution and multiplanar capabilities, allows for accurate preoperative localization and postoperative assessment of syringomyelia. Recent advances in dynamic MRI techniques have made it possible to evaluate normal and abnormal cerebrospinal fluid (CSF) flow at the foramen magnum, within the syrinx, and in the spinal subarachnoid space, without invasion of the closed CSF system. These developments have yielded substantial information concerning various aspects of syringomyelia. However, many issues related to the pathophysiology and treatment of syringomyelia remain controversial. This book contains the scientific contributions presented at the international sym posium "Syringomyelia 2000:' held in Kobe, Japan, June 16-17,2000. The purpose of the symposium was to bring together experts in the fields of neurosurgery, neurol ogy, and neuropathology, in order to enhance the level and scope of their knowledge by making them more aware of work done in complementary fields. The contribu tions also report on clinical and basic studies pertinent to the topic of the sympo sium. This volume thus represents a comprehensive description of the state of the art regarding this disease in the hope that it may help to define comprehensively what is already known and to find new ways toward a better understanding of the patho physiology, diagnosis, and treatment of syringomyelia.