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Dosage Forms, Formulation Developments and Regulations, Volume One
in the Recent and Future Trends in Pharmaceutics series, explores
aspects of pharmaceutics, with an original approach focused on
technology, novelties and future trends in the field. The book
discusses the most recent developments in pharmaceutical
preformulation and formulation studies, biopharmaceutics and novel
pharmaceutical formulations, regulatory affairs, and good
manufacturing practices. Exciting areas such as formulation
strategies, optimization techniques, the biopharmaceutical
classification system, and pharmaceutical aerosols are included.
The field of pharmaceutics is highly dynamic and rapidly expanding
day-by-day, so it demands a variety of amplified efforts for
designing and developing pharmaceutical processes and formulation
strategies. This is an essential reference for researchers in
academia and industry as well as advanced graduate students in
pharmaceutics.
Advanced Nanoformulations: Theranostic Nanosystems, Volume Three
examines the applications of nanotherapeutic systems and
nanodiagnostics in relation to polymeric nanosystems. In the last
decade, numerous biopolymers have been utilized to prepare
polymeric nanosystems for therapeutic applications. These
biopolymers include polylactic acid, polylactide-co-glycolide,
polycaprolactone, acrylic polymers, cellulose and cellulose
derivatives, alginates, chitosan, gellan gum, gelatin, albumin,
chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum
tragacanth, xanthan gum, and starches. Besides these biopolymers,
grafted polymers are also being used as advanced polymeric
materials to prepare many theranostic nanocarriers and
nanoformulations. This book explores the array of polymeric
nanosystems to understand therapeutic potentials. It will be useful
to pharmaceutical scientists, including industrial pharmacists and
analytical scientists, health care professionals, and regulatory
scientists actively involved in the pharmaceutical product and
process development of tailor-made polysaccharides in drug delivery
applications.
Concepts and Methodology in Cancer Diagnostics: An Immunological,
Biochemical and Molecular Approach provides an exclusive
combination of all basics and recent techniques, methodology, and
advancements in the field of cancer diagnostics. With a strong
focus on the procedures and techniques involved in cancer
diagnostics, content also gives insight into the molecular tests
required for different tumors for the administration of targeted
drugs and precision medicine. In 11 chapters Concepts and
Methodology in Cancer diagnostics: An Immunological, Biochemical
and Molecular Approach introduces the methods and technologies
based on DNA and RNA based biomarkers, biochemical and
immunological markers, genetic signatures, epigenetic changes and
exosomes in blood, and tissue and body fluids. There is also
additional focus on specific mutations and expression markers that
are utilized for the diagnosis of cancers of unknown primary origin
(CUPs). Concepts and Methodology in Cancer Diagnostics: An
Immunological, Biochemical and Molecular Approach presents a
compilation of imperative topics and includes lists of the
necessary materials and reagents needed, step-by-step instructions,
readily reproducible laboratory protocols, as well as tips on
troubleshooting and known pitfalls. This book is a valuable
resource for medical professionals and researchers to understand
the concepts of validated protocols and methodology in diagnosing
cancer, its prognosis, and predictive value.
Nanostructured Materials for Tissue Engineering introduces the key
properties and approaches involved in using nanostructured
materials in tissue engineering, including functionalization,
nanotechnology-based regenerative techniques, toxicological and
biocompatible aspects. A broad range of nanomaterial types are
covered, from polymer scaffolds and nanocomposites to gold
nanoparticles and quantum dots. This book aids the reader in
materials selection, as well as matching to the best applications,
including bone, skin, pulmonary or neurological tissue engineering.
Users will find this book to be an up-to-date review on this
fast-changing field that is ideal for materials scientists, tissue
engineers, biomedical engineers, and pharmaceutical scientists.
Plant Polysaccharides as Pharmaceutical Excipients explores
innovative techniques and applications of plant-derived
polysaccharides as pharmaceutical excipients. Plant polysaccharides
are sustainable, renewable and abundantly available, offering
attractive properties in terms of water solubility, swelling
ability, non-toxicity and biodegradability. These qualities have
resulted in extensive exploration into their applications as
excipients in a variety of pharmaceutical dosage forms. This book
takes a comprehensive, application-oriented approach, drawing on
the very latest research that includes sources, classification and
extraction methods of plant polysaccharides. Subsequent chapters
focus on plant polysaccharides for individual pharmaceutical
applications, enabling the reader to understand their preparation
for specific targeted uses. Throughout the book, information is
supported by illustrations, chemical structures, flow charts and
data tables, providing a clear understanding. Finally, future
perspectives and challenges are reviewed and discussed.
Design and Applications of Theranostic Nanomedicines reviews the
composition and design of various nanomedicines for theranostic
applications, helping readers to make informed decisions when
exploring novel treatments for disease. This book introduces
readers to theranostic nanostructures as nanomedicines, beginning
with a balanced look at the associated challenges, costs and
benefits. The next section goes on to detail a range of different
theranostic nanomedicines and their design, from nanodispersions
and nanogels to exosomes and polymeric micelles. A variety of
applications is covered, including in the treatment of pulmonary
diseases, neurological disorders, cancers and more. The book also
takes a look at the toxicological implications of nanotheranostics,
an important aspect of any therapy or treatment. Design and
Applications of Theranostic Nanomedicines provides a snapshot of
the state-of-the-art, and will be of use to materials scientists,
biomedical engineers and pharmaceutical scientists with an interest
in nanotechnology and theranostics.
Advancements in Polymer-Based Membranes for Water Remediation
describes the advanced membrane science and engineering behind the
separation processes within the domain of polymer-based membrane
systems in water remediation. Emphasis has been put on several
aspects, ranging from fundamental concepts to the commercialization
of pressure and potential driven membranes, updated with the latest
technological progresses, and relevant polymer materials and
application potential towards water treatment systems. Also
included in this book are advances in polymers for membrane
application in reverse osmosis, nanofiltration, ultrafiltration,
microfiltration, forward osmosis, and polymeric ion-exchange
membranes for electrodialysis and capacitive deionization. With its
critical analyzes and opinions from experts around the world, this
book will garner considerable interest among actual users, i.e.,
scientists, engineers, industrialists, entrepreneurs and students.
Nanostructured Materials for Visible Light Photocatalysis describes
the various methods of synthesizing different classes of
nanostructured materials that are used as photocatalysts for the
degradation of organic hazardous dyes under visible light
irradiation. The first three chapters include a general
introduction, basic principles, mechanisms, and synthesis methods
of nanomaterials for visible light photocatalysis. Recent advances
in carbon, bismuth series, transition metal oxide and
chalcogenides-based nanostructured materials for visible light
photocatalysis are discussed. Later chapters describe the role of
phosphides, nitrides, and rare earth-based nanostructured-based
materials in visible light photocatalysis, as well as the
characteristics, synthesis, and fabrication of photocatalysts. The
role of doping, composites, defects, different facets, morphology
of nanostructured materials and green technology for efficient dye
removal under visible-light irradiation are also explored. Other
topics covered include large-scale production of nanostructured
materials, the challenges in present photocatalytic research, the
future scope of nanostructured materials regarding environmental
hazard remediation under visible light, and solar light harvesting.
This book is a valuable reference to researchers and enables them
to learn more about designing advanced nanostructured materials for
wastewater treatment and visible-light irradiation.
Polymer Nanocomposites Containing Graphene: Preparation, Properties
and Applications provides detailed up-to-date information on the
characterization, synthesis, processing, properties and application
of these materials. Key topics that are covered in the book
include: the methods of synthesis and preparation of graphene as
well as different processes and methods of functionalization and
modification of graphene for improving composite properties. The
preparation techniques focus on which method is advantageous for
getting improvements in properties along with their drawbacks. The
structure and property relationships are also discussed in detail.
The issues related to graphene dispersion in polymer matrices is
also addressed as well as the use of graphene as reinforcement in
thermoset resins. The different properties of the composites like
mechanical, electrical, dielectric, thermal, rheological,
morphology, spectroscopy, electronic, optical, and toxicity are
reviewed from the geometrical and functional point of view.
Applications cover electrical and electronic fields, flame and fire
retardancy, structural, sensing and catalysis, membrane, in fuel
cell and solar energy, hydrogen production, aerospace engineering,
packaging, and biomedical/bioengineering fields. Up-to-date patents
on graphene-polymer nanocomposites are also covered. Those working
in graphene-based materials will benefit from the detailed
knowledge presented in this book on graphene synthesis, composite
preparation methods, and the related problems associated with them.
The book will enable researchers to select the appropriate
composite as per their respective field of application.
Advanced and Modern Approaches for Drug Delivery explores novel
approaches currently used for drug delivery, including the must
up-to-date techniques and technology. The approaches discussed
allow pharmaceutical scientists to design effective drug delivery
systems or devices for the management and treatment of numerous
diseases and conditions. Detailed information on a wide variety of
subjects, including dendrimers, lipid nanostructures, solid lipid
nanoparticles, stimuli-responsive smart systems, self-assembled
protein-drug nanoparticles, nanoconjugate formulations, nanofibers,
iontophoretic systems, microneedle systems, ultra-sound triggered
systems, targeted carrier-based intracellular delivery systems,
resealed erythrocyte-based systems, 3 D-printing tool,
site-specific monoclonal antibodies, and bio-inspired systems are
all comprehensively discussed. With contributions from those in
academia and industry, this book is an excellent reference for all
those needing to understand drug delivery systems.
Waste Management in the Textiles Industry explores and explains the
latest technologies and best practices for an integrated approach
to the management and treatment of wastes generated in this
industry.
Alginates in Drug Delivery explores the vital precepts, basic and
fundamental aspects of alginates in pharmaceutical sciences,
biopharmacology, and in the biotechnology industry. The use of
natural polymers in healthcare applications over synthetic polymers
is becoming more prevalent due to natural polymers'
biocompatibility, biodegradability, economic extraction and ready
availability. To fully utilize and harness the potential of
alginates, this book presents a thorough understanding of the
synthesis, purification, and characterization of alginates and
their derivative. This book collects, in a single volume, all
relevant information on alginates in health care, including recent
advances in the field. This is a highly useful resource for
pharmaceutical scientists, health care professionals and regulatory
scientists actively involved in the pharmaceutical product and
process development of natural polymer containing drug delivery, as
well as postgraduate students and postdoctoral research fellows in
pharmaceutical sciences.
Sustainable Technologies for Fashion and Textiles combines the
latest academic research and industrial practices to shed light on
a wide range of activities that influence how the textiles industry
affects the natural environment. Pressure from regulators,
customers and other stakeholders has pressed companies to translate
general sustainability concepts and ideas into business practices.
This is leading to improvements in how the industry consumes water,
electricity and chemicals, and to a reduction in the amount of
waste generated by textile processes. This book groups approaches
to these topics under four themes, fiber, yarn and fabric
production, chemical processing, garment manufacturing and
recycling.
Superhydrophobic Polymer Coatings: Fundamentals, Design,
Fabrication, and Applications offers a comprehensive overview of
the preparation and applications of polymer coatings with
superhydrophobicity, guiding the reader through advanced techniques
and scientific principles. Sections present detailed information on
the fundamental theories and methods behind the preparation of
superhydrophobic polymer coatings and demonstrate the current and
potential applications of these materials, covering a range of
novel and marketable uses across industry, including coatings with
properties such as foul resistance and self-cleaning, anti-icing
and ice-release, corrosion inhibition, antibacterial,
anti-reflection, slip and drag reduction, oil-water separation, and
advanced medical applications. This book is a highly valuable
resource for academic researchers, scientists and advanced students
working on polymer coatings or polymer surface modifications, as
well as professionals across polymer science, polymer chemistry,
plastics engineering, and materials science. The detailed
information in this book will also be of great interest to
scientists, R&D professionals, product designers and engineers
who are looking to develop products with superhydrophobic coatings.
Single-Phase, Two-Phase and Supercritical Natural Circulation
Systems provides readers with a deep understanding of natural
circulation systems. This book equips the reader with an
understanding on how to detect unstable loops to ensure plant
safety and reliability, calculate heat transport capabilities, and
design effective natural circulation loops, stability maps and
parallel channel systems. Each chapter begins with an introduction
to the circulation system before discussing each element in detail
and analyzing its effect on the performance of the system. The book
also presents thermosyphon heat transport devices in nuclear and
other industrial plants, a common information need for students and
researchers alike. This book is invaluable for engineers,
designers, operators and consultants in nuclear, mechanical,
electrical and chemical disciplines.
Advances of Computational Fluid Dynamics in Nuclear Reactor Design
and Safety Assessment presents the latest computational fluid
dynamic technologies. It includes an evaluation of safety systems
for reactors using CFD and their design, the modeling of Severe
Accident Phenomena Using CFD, Model Development for Two-phase
Flows, and Applications for Sodium and Molten Salt Reactor Designs.
Editors Joshi and Nayak have an invaluable wealth of experience
that enables them to comment on the development of CFD models, the
technologies currently in practice, and the future of CFD in
nuclear reactors. Readers will find a thematic discussion on each
aspect of CFD applications for the design and safety assessment of
Gen II to Gen IV reactor concepts that will help them develop cost
reduction strategies for nuclear power plants.
Tailor-Made Polysaccharides in Drug Delivery provides extensive
details on all the vital precepts, basics and fundamental aspects
of tailored polysaccharides in the pharmaceutical and
biotechnological industry for understanding and developing high
quality products. The book offers a comprehensive resource to
understand the potential of the materials in forming new drug
delivery methods. It will be useful to pharmaceutical scientists,
chemical engineers, and regulatory scientists and students actively
involved in pharmaceutical product and process development of
tailored-made polysaccharides in drug delivery applications. The
utilization of natural polymeric excipients in numerous healthcare
applications demand the replacement of the synthetic polymers with
the natural ones due to their biocompatibility, biodegradability,
economic extraction and readily availability. The reality behind
the rise in importance of these natural materials is that these
sources are renewable if grown in a sustainable means and they can
tender incessant supply of raw materials. Amongst these natural
polymers, polysaccharides are considered as excellent excipients
because of its non-toxic, stable, biodegradable properties. Several
research innovations have been made on applications of
polysaccharides in drug delivery.
Systems of Nanovesicular Drug Delivery provides a thorough insight
into the complete and up-to-date discussions about the preparation,
properties and drug delivery applications of various nanovesicles.
This volume discusses cubosomes, proniosomes and niosomes,
dendrimerosomes and other new and effective approaches for drug
delivery. It will be a valuable title and resource for academics
and pharmaceutical scientists, including industrial pharmacists,
analytical scientists, health care professionals and regulatory
scientists actively involved in pharmaceutical products and process
development of tailor-made polysaccharides in drug delivery
applications. Recently, there have been a number of outstanding
nanosystems in nanovesicular carrier-forms (such as nanoemulsions,
self-nanoemulsifying systems, nanoliposomes, nanotransferosomes,
etc.), that have been researched and developed for efficient drug
delivery by many formulators, researchers and scientists. However,
no previously published books have covered all these drug delivery
nanovesicles collectively in a single resource.
Applications of Nanovesicular Drug Delivery provides thorough
insights and a complete and updated discussion on the preparation,
properties and drug delivery applications of various nanovesicles.
This volume will discuss target-specific drug application, such as
ocular, transdermal, nasal, intravenous and oral delivery. This
title is a valuable resource for academics, pharmaceutical
scientists, including industrial pharmacists and analytical
scientists, health care professionals and regulatory scientists
actively involved in pharmaceutical products and process
development of tailored-made polysaccharides in drug delivery
applications. Recently, there have been a number of outstanding
nanosystems in nanovesicular carrier-forms (such as nanoemulsions,
self-nanoemulsifying systems, nanoliposomes, nanotransferosomes,
etc.), that have been researched and developed for efficient drug
delivery by many formulators, researchers and scientists. However,
no previously published books have covered all these drug delivery
nanovesicles collectively in a single resource.
Gellan Gum as a Biomedical Polymer details key topics and
fundamental aspects of gellan gum and its biomedical applications
in drug delivery, proteins and peptides delivery, cell delivery,
tissue engineering, wound dressings and enzyme immobilizations in
developing high quality products. Sections introduce gellan gum,
its source, production and gelation mechanism, discuss biomedical
materials, and provides ways it can be used for biomedical
applications. The book also examines the used of gellan gum as
pharmaceutical excipients for drug delivery. Future developments
and challenges round out the book’s coverage. With contributions
for an international group of experts, this book is a useful
reference for scientists, researchers and those in industry engaged
in biomedical product development using natural polysaccharides.
Digital image processing is a field that is constantly improving.
Gaining high-level understanding from digital images is a key
requirement for computing. One aspect of study that is assisting
with this advancement is fractal theory. This new science has
gained momentum and popularity as it has become a key topic of
research in the area of image analysis. Examining Fractal Image
Processing and Analysis is an essential reference source that
discusses fractal theory applications and analysis, including
box-counting analysis, multi-fractal analysis, 3D fractal analysis,
and chaos theory, as well as recent trends in other soft computing
techniques. Featuring research on topics such as image compression,
pattern matching, and artificial neural networks, this book is
ideally designed for system engineers, computer engineers,
professionals, academicians, researchers, and students seeking
coverage on problem-oriented processing techniques and imaging
technologies.
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