This timely and thought-provoking collection explores the ways in which psychological science interacts with and addresses gender across varied subdisciplines in the field, from a feminist viewpoint. A particular aim of this volume is to move the conversation of gender in psychology beyond a difference-only paradigm. Veteran and emerging feminist scholars survey the handling of sex and gender issues across psychology, and describe how feminist perspectives and methodologies can and should be applied to enhance the field itself, but also in the service of social justice in the various cultures of corporations, academia, and the global stage. Contributions span theoretical advances, latest empirical findings, and real-world advocacy, with instructive and illuminating first-person accounts detailing challenges and rewards of feminist scholarship and practice in psychology. Throughout the volume, chapters document a dynamic field in its evolution from the traditional, two-dimensional study of gender-based differences to concerted multidisciplinary approaches, to cutting edge feminist theoretical and methodological advances such as intersectionality to understand gender in context. The volume is divided into three distinct sections. The first covers current theory and research in psychological science that considers gender beyond a difference-only paradigm. Then, leading feminist scholars reflect upon their own experiences in their respective subdisciplines. Finally, the third section explores innovative best practices and applications for feminist psychological science. Highlights of the coverage: * Beyond difference: Gender as a quality of social settings. * Adventures in feminist health psychology: Teaching about and conducting feminist psychological science. * Mind the thigh gap? Bringing feminist psychological science to the masses. * Feminist psychologists and institutional change in universities. With its stimulating compilation of theories, research, and applications, Feminist Perspectives On Building A Better Psychological Science of Gender is one of the most forward-thinking and innovative treatments of the field in recent years. It is a significant and important text for all psychologists, women's and gender studies specialists, social science researchers, and all those interested in using evidence-based psychological science to create a more just and equitable world.

This timely and thought-provoking collection explores the ways in which psychological science interacts with and addresses gender across varied subdisciplines in the field, from a feminist viewpoint. A particular aim of this volume is to move the conversation of gender in psychology beyond a difference-only paradigm. Veteran and emerging feminist scholars survey the handling of sex and gender issues across psychology, and describe how feminist perspectives and methodologies can and should be applied to enhance the field itself, but also in the service of social justice in the various cultures of corporations, academia, and the global stage. Contributions span theoretical advances, latest empirical findings, and real-world advocacy, with instructive and illuminating first-person accounts detailing challenges and rewards of feminist scholarship and practice in psychology. Throughout the volume, chapters document a dynamic field in its evolution from the traditional, two-dimensional study of gender-based differences to concerted multidisciplinary approaches, to cutting edge feminist theoretical and methodological advances such as intersectionality to understand gender in context. The volume is divided into three distinct sections. The first covers current theory and research in psychological science that considers gender beyond a difference-only paradigm. Then, leading feminist scholars reflect upon their own experiences in their respective subdisciplines. Finally, the third section explores innovative best practices and applications for feminist psychological science. Highlights of the coverage: * Beyond difference: Gender as a quality of social settings. * Adventures in feminist health psychology: Teaching about and conducting feminist psychological science. * Mind the thigh gap? Bringing feminist psychological science to the masses. * Feminist psychologists and institutional change in universities. With its stimulating compilation of theories, research, and applications, Feminist Perspectives On Building A Better Psychological Science of Gender is one of the most forward-thinking and innovative treatments of the field in recent years. It is a significant and important text for all psychologists, women's and gender studies specialists, social science researchers, and all those interested in using evidence-based psychological science to create a more just and equitable world.

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It has also been shown that defects in this network, predominantly within the ATM mediated signaling pathway, are commonly observed in cancers and may be a primary event during tumorigenesis. Such defects may promote a genomically unstable environment, facilitating the persistence of mutations, any of which may provide a growth or survival advantage to the developing tumor. In addition, these somatic defects provide opportunities to exploit a reliance on remaining repair pathways for survival, a process which has been termed synthetic lethality. As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents that may have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR. In this book we will review a series of important topics that are of great interest to a broad range of academic, industrial and clinical researchers, including the basic science of the DDR, its role in tumorigenesis and in dictating response to DNA damaging drugs and IR. Additionally, we will focus on the several proteins that have been targeted in attempts to provide drug candidates, each of which appear to have quite distinct profiles and could represent very different opportunities to provide patient benefit.

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It has also been shown that defects in this network, predominantly within the ATM mediated signaling pathway, are commonly observed in cancers and may be a primary event during tumorigenesis. Such defects may promote a genomically unstable environment, facilitating the persistence of mutations, any of which may provide a growth or survival advantage to the developing tumor. In addition, these somatic defects provide opportunities to exploit a reliance on remaining repair pathways for survival, a process which has been termed synthetic lethality. As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents that may have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR. In this book we will review a series of important topics that are of great interest to a broad range of academic, industrial and clinical researchers, including the basic science of the DDR, its role in tumorigenesis and in dictating response to DNA damaging drugs and IR. Additionally, we will focus on the several proteins that have been targeted in attempts to provide drug candidates, each of which appear to have quite distinct profiles and could represent very different opportunities to provide patient benefit.