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Mice are used as model organisms across a wide range of fields in
science today--but it is far from obvious how studying a mouse in a
maze can help us understand human problems like alcoholism or
anxiety. How do scientists convince funders, fellow scientists, the
general public, and even themselves that animal experiments are a
good way of producing knowledge about the genetics of human
behavior? In Model Behavior, Nicole C. Nelson takes us inside an
animal behavior genetics laboratory to examine how scientists
create and manage the foundational knowledge of their field.
Behavior genetics is a particularly challenging field for making a
clear-cut case that mouse experiments work, because researchers
believe that both the phenomena they are studying and the animal
models they are using are complex. These assumptions of complexity
change the nature of what laboratory work produces. Whereas
historical and ethnographic studies traditionally portray the
laboratory as a place where scientists control, simplify, and
stabilize nature in the service of producing durable facts, the
laboratory that emerges from Nelson's extensive interviews and
fieldwork is a place where stable findings are always just out of
reach. The ongoing work of managing precarious experimental systems
means that researchers learn as much--if not more--about the impact
of the environment on behavior as they do about genetics. Model
Behavior offers a compelling portrait of life in a
twenty-first-century laboratory, where partial, provisional answers
to complex scientific questions are increasingly the norm.
Mice are used as model organisms across a wide range of fields in
science today--but it is far from obvious how studying a mouse in a
maze can help us understand human problems like alcoholism or
anxiety. How do scientists convince funders, fellow scientists, the
general public, and even themselves that animal experiments are a
good way of producing knowledge about the genetics of human
behavior? In Model Behavior, Nicole C. Nelson takes us inside an
animal behavior genetics laboratory to examine how scientists
create and manage the foundational knowledge of their field.
Behavior genetics is a particularly challenging field for making a
clear-cut case that mouse experiments work, because researchers
believe that both the phenomena they are studying and the animal
models they are using are complex. These assumptions of complexity
change the nature of what laboratory work produces. Whereas
historical and ethnographic studies traditionally portray the
laboratory as a place where scientists control, simplify, and
stabilize nature in the service of producing durable facts, the
laboratory that emerges from Nelson's extensive interviews and
fieldwork is a place where stable findings are always just out of
reach. The ongoing work of managing precarious experimental systems
means that researchers learn as much--if not more--about the impact
of the environment on behavior as they do about genetics. Model
Behavior offers a compelling portrait of life in a
twenty-first-century laboratory, where partial, provisional answers
to complex scientific questions are increasingly the norm.
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