Metabolic Syndrome refers to the clustering of risk factors including obesity, elevated blood pressure (hypertension), elevated blood sugars, dyslipidaemia (high triglycerides & low HDL concentration) and hence increased risk for developing many serious medical conditions including type 2 diabetes, myocardial infarction, and stroke & early death. Lifestyle changes, one of the main factor, due to fast increasing urbanization, especially in developing countries like India, has led to the development of serious health problems like obesity, hypertension, diabetes, etc. which in turn lead to the complications like Metabolic Syndrome . About one third of the urban population in India's major cities have Metabolic Syndrome. The National Cholesterol Education Program Adult Treatment Panel III simplified the definition of Metabolic Syndrome to make it user friendly for medical practitioners. Our study included faculty members of different professional streams using NCEP ATPIII criteria and was concluded that medical faculty had maximum percentage of subjects having Metabolic Syndrome. Early lifestyle modification leads to the reduction in these risk factors and hence to Metabolic Syndrome.

In India, cardiovascular diseases (CVDs) are estimated to be responsible for 1.5 million deaths annually. Indeed, it is estimated that by 2020, CVDs will be the largest cause of mortality and morbidity in India. Hypertension is a major risk factor for CVDs, including stroke and myocardial infarction, and its burden is increasing disproportionately in developing countries. It is estimated that around two-thirds of those with people with hypertension worldwide were living in developing countries (639 million) in 2000, and that this would rise to three-quarters living in developing countries (1.15 billion) by 2025. Uric acid builds up when the body makes too much of it, fails to excrete it or both. It is a metabolic product resulting from purine. It remains possible that uric acid is a marker for xanthine oxidase-associated oxidants and that the latter could be driving the hypertensive response. However, the evidence suggests that uric acid is a true modifying and possibly causal factor for human primary hypertension. Hence, early management of hyperuricemia might delay the development of essential hypertension.

Tablets are solid unit dosage form of medicaments with or without suitable diluents and prepared either by molding or compression. They are solid, flat or biconvex disc in shape. They vary greatly in shape, size and weight which depend upon amount of medicament used and mode of administration. They also vary in hardness, thickness, disintegration and dissolution characteristics and in other aspects depending upon their intended use and method of manufacture. Tablets are the most widely used solid dosage form of medicament. Because of their advantages their popularity is continuously increasing day by day. Hypertension is a very common disorder, particularly past middle age. It is not a disease in itself, but it is an important risk factor for cardiovascular mortality and morbidity. The WHO-ISH guidelines defined it to 140 mm Hg systolic and 90 mm Hg diastolic, through risk appears to increase even above 120/90 mm Hg.