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Calreticulin (Hardcover, 2nd ed. 2003): Paul Eggleton, Marek Michalak Calreticulin (Hardcover, 2nd ed. 2003)
Paul Eggleton, Marek Michalak
R4,394 Discovery Miles 43 940 Ships in 10 - 15 working days

The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Calreticulin has been implicated to affect diverse cellular function and play a role in many pathologies including protein folding disorders, cardiac pathologies, cancer and autoimmunity. This book contains contributions from the world leaders in the area of endoplasmic reticulum function, protein folding, Calcium homeostasis and autoimmunity. It raises many intriguing questions about calreticulin, calnexin and the endoplasmic reticulum and gives a unique opportunity to realize the significance of these calcium-binding chaperones. The book is unique in every respect and we are not aware of any other publication focusing on these aspects of endoplasmic reticulum biology. Because of a central role of endoplasmic reticulum, calreticulin and calnexin in virtually all cellular functions, the book should be of interest to everyone in the biological sciences.

Systemic Lupus Erythematosus - Methods and Protocols (Hardcover, 2014): Paul Eggleton, Frank J. Ward Systemic Lupus Erythematosus - Methods and Protocols (Hardcover, 2014)
Paul Eggleton, Frank J. Ward
R4,891 R3,746 Discovery Miles 37 460 Save R1,145 (23%) Ships in 12 - 19 working days

Systemic Lupus Erythematosus: Methods and Protocols describe a number of genetic, biochemical and immunological techniques. These techniques provide an advancing understanding of the pathology, breakdown of the immune system and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Systemic Lupus Erythematosus: Methods and Protocols appeal to biomedical and clinical scientists in a number of pathology disciplines at the doctoral and post-doctoral level.

Phylogenetics and Ecology, Volume 17 (Hardcover): Paul Eggleton, Richard I. Vane-Wright Phylogenetics and Ecology, Volume 17 (Hardcover)
Paul Eggleton, Richard I. Vane-Wright
R3,692 Discovery Miles 36 920 Ships in 12 - 19 working days

The relationship between systematics and ecology has recently been invigorated, and developed a long way from the "old" field of comparative biology. This change has been two-fold. Advances in phylogenetic research have allowed explicit phylogenetic hypotheses to be constructed for a range of different groups of organisms, and ecologists are now more aware that organism traits are influenced by the interaction of past and present. This volume discusses the impact of these modern phylogenetic methods on ecology, especially those using comparative methods.
Although unification of these areas has proved difficult, a number of conclusions can be drawn from the text. These include the need for a "working" bridge between evolutionary biologists using logic-based cladistic methods and those using probability-based statistical methods, for care in the selection of tree types for comparative studies and for systematists to attempt to analyse ecologically important groups.
Comparative ecologists and systematists need to come together to develop these ideas further, but this volume presents a very useful starting point for all those interested in systematics and ecology.

Systemic Lupus Erythematosus - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014): Paul... Systemic Lupus Erythematosus - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014)
Paul Eggleton, Frank J. Ward
R3,151 Discovery Miles 31 510 Ships in 10 - 15 working days

Systemic Lupus Erythematosus: Methods and Protocols describe a number of genetic, biochemical and immunological techniques. These techniques provide an advancing understanding of the pathology, breakdown of the immune system and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Systemic Lupus Erythematosus: Methods and Protocols appeal to biomedical and clinical scientists in a number of pathology disciplines at the doctoral and post-doctoral level.

Calreticulin (Paperback, 2nd ed. 2003. Softcover reprint of the original 2nd ed. 2003): Paul Eggleton, Marek Michalak Calreticulin (Paperback, 2nd ed. 2003. Softcover reprint of the original 2nd ed. 2003)
Paul Eggleton, Marek Michalak
R4,328 Discovery Miles 43 280 Ships in 10 - 15 working days

The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Calreticulin has been implicated to affect diverse cellular function and play a role in many pathologies including protein folding disorders, cardiac pathologies, cancer and autoimmunity. This book contains contributions from the world leaders in the area of endoplasmic reticulum function, protein folding, Calcium homeostasis and autoimmunity. It raises many intriguing questions about calreticulin, calnexin and the endoplasmic reticulum and gives a unique opportunity to realize the significance of these calcium-binding chaperones. The book is unique in every respect and we are not aware of any other publication focusing on these aspects of endoplasmic reticulum biology. Because of a central role of endoplasmic reticulum, calreticulin and calnexin in virtually all cellular functions, the book should be of interest to everyone in the biological sciences.

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