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More than 70 years have elapsed since U. S. von Euler and I. H.
Gaddum dis- covered an unidentified depressor substance in the
brain and gut. The effects of the powdery extracts were marked as
'P' on the kymograph tracings, and the nondescript name of
'substance P' still carries the breath of this adventurous period.
In the 1960s, substance P returned in another disguise, staging as
a hypothalamic peptide that causes copious salivary secretion (see
chapter by F. Lembeck and I. Donnerer). This time, though, the
mysterious substance was tracked down by S. E. Leeman and her
collaborators as an undecapeptide, after it had eluded its
identification for some 40 years. Substance P turned out to be the
mammalian counterpart of a family of peptides which had been
extracted from amphibian and nonvertebrate species and which had
been given the name 'tachykinins' by V. Erspamer. Soon novel
members of this peptide family were discovered, and in mammals
substance P was joined by neurokinin A and neu- rokinin B. The
presence of tachykinins in frog skin as well as in venoms and
toxins of microbes and arachnids raises the possibility that these
peptides re- present an old system of biological weapons that have
been transformed to a particular messenger system in mammals.
More than 70 years have elapsed since U. S. von Euler and I. H.
Gaddum dis- covered an unidentified depressor substance in the
brain and gut. The effects of the powdery extracts were marked as
'P' on the kymograph tracings, and the nondescript name of
'substance P' still carries the breath of this adventurous period.
In the 1960s, substance P returned in another disguise, staging as
a hypothalamic peptide that causes copious salivary secretion (see
chapter by F. Lembeck and I. Donnerer). This time, though, the
mysterious substance was tracked down by S. E. Leeman and her
collaborators as an undecapeptide, after it had eluded its
identification for some 40 years. Substance P turned out to be the
mammalian counterpart of a family of peptides which had been
extracted from amphibian and nonvertebrate species and which had
been given the name 'tachykinins' by V. Erspamer. Soon novel
members of this peptide family were discovered, and in mammals
substance P was joined by neurokinin A and neu- rokinin B. The
presence of tachykinins in frog skin as well as in venoms and
toxins of microbes and arachnids raises the possibility that these
peptides re- present an old system of biological weapons that have
been transformed to a particular messenger system in mammals.
Koordinations-Screening bei verschiedenen Testbewegungen im Bereich
der Grundmotorik. Bei Kindern lassen sich Koordinationsschwchen
noch leicht verbessern. Voraussetzung ist das Erkennen der
Koordinationsprobleme. Bei ber 6000 Schlern wurden Haltungs- und
Koordinationsuntersuchungen durchgefhrt, auffllige Bewegungsmuster
dokumentiert und individuelle Trainingsplne erstellt.
Videoaufzeichnungen beim Gehen, Laufen, Einbeinstehen,
Einbeinspringen, Seitspringen und Hampelmannspringen zeigen
Bewegungsstrken und Schwchen der Kinder.
Das Baumaterial Ziegel erfreut sich nach wie vor grosser Nachfrage.
Dieser Sonderband der Reihe Baukonstruktionen stellt seine
Anwendung im Hochbau, speziell im Ziegelmauerwerk, aber auch in
Ziegeldecken, Ziegelfertigteilen und als Dachziegel dar.
Systematisch aufgebaut, bietet das Buch eine Vielfalt an
Informationen: eine Materialkunde, Faustformeln und Grundlagen
sowie Anwendungen im Verbund. Fur die Neuauflage dieses Handbuches
wurden samtliche Kapitel durchgesehen und aktualisiert, auch neue
Normen berucksichtigt. Neue Themen wie Bauanschlussfugen,
Einbruchshemmung und Prufvorschriften wurden aufgenommen, die
Mauerwerksbemessung um Rechenbeispiele erganzt. Die erhoehte Anzahl
der Ausfuhrungsbeispiele wurde in einem eigenen Beispielteil
anschaulich zusammengefasst.
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