Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others.

Handbook of the Biology of Aging, Ninth Edition, provides a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology. The book focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and metabolomics methodologies applied to aging related problems. Sections cover longevity pathways and interventions that modulate aging, innovative tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, and much more.

Peter Hornsby's Decorated Biscuit Tins tells the story of a highly successful marketing technique operated in Britain, the United States, and many other parts of the world from the Victorian period up to the second World War. Biscuit or cookie makers discovered that their products sold better and lasted longer if they were packed in tins. The first plain, simple containers were replaced by elaborately decorated printed tins, many made to represent a whole range of fascinating domestic and family objects. These colorful and novel tins helped sell the biscuits and then remained in the home to be used as storage boxes or played with as toys, until they became the source of interest for today. Thousands of designs were made by the world's leading biscuit makers, and examples can still be discovered in trunks in Grannie's attic, filled with seed packets in the garden shed, on a shelf in the garage, or in any number of antique shops.