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This volume presents recent data on the latest achievements in new
and emerging technologies for biomarkers and for innovations in
their assessment. The chapters cover topics such as activation of
microglia and macrophages in neurodegenerative diseases; oxidative
stress and cellular dysfunction in neurodegenerative diseases; TSPO
PET imaging as a biomarker of neuroinflammation in
neurodegenerative disorders; and imaging biomarkers in Huntington's
disease and amyotrophic lateral sclerosis. In the Neuromethods
series style, chapters include the kind of detail and key advice
from the specialists needed to get successful results in your
laboratory. Cutting-edge and comprehensive, Neurodegenerative
Diseases Biomarkers: Towards Translating Research to Clinical
Practice is a valuable resource for both experimental and clinical
experts in the field of neurodegenerative diseases who are looking
to expand their knowledge of novel biomarkers in different types of
neurodegenerative diseases.
This volume presents recent data on the latest achievements in new
and emerging technologies for biomarkers and for innovations in
their assessment. The chapters cover topics such as activation of
microglia and macrophages in neurodegenerative diseases; oxidative
stress and cellular dysfunction in neurodegenerative diseases; TSPO
PET imaging as a biomarker of neuroinflammation in
neurodegenerative disorders; and imaging biomarkers in Huntington's
disease and amyotrophic lateral sclerosis. In the Neuromethods
series style, chapters include the kind of detail and key advice
from the specialists needed to get successful results in your
laboratory. Cutting-edge and comprehensive, Neurodegenerative
Diseases Biomarkers: Towards Translating Research to Clinical
Practice is a valuable resource for both experimental and clinical
experts in the field of neurodegenerative diseases who are looking
to expand their knowledge of novel biomarkers in different types of
neurodegenerative diseases.
From pathology to treatment, MicroRNAs in Diseases and Disorders
highlights the role of microRNAs (miRNAs) in the development and
progression of a variety of diseases, including cancer,
neurological disease, endocrine disease and autoimmune disease, and
underscores the utilization of miRNA targets in the treatment of
these conditions. Providing a comprehensive account, this book also
includes the identification of miRNAs as diagnostic and prognostic
biomarkers for disease, as well as evaluates translational value
from clinical trials using synthesized and functionalized miRNA
mimics and inhibitors. With a global contribution list and chapters
from leading experts across the field, MicroRNAs in Diseases and
Disorders is an invaluable reference to miRNA researchers and
health professionals in a variety of disease areas in government,
academia and industry. The book will also appeal to pharmaceutical
and medicinal chemists with an interest in miRNA targeting
therapeutics, as well as to advanced students in chemical biology
and drug discovery.
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