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The oceans cover over 70% of our planet. They are host to a biodiversity of tremendous wealth. Its preservation is now a global priority featuring in several international conventions and a confirmed objective of European policies and national strategies. Understanding the dynamics and the uses of the marine biodiversity is a genuine scientific challenge. Fourteen international experts have got together and identified five priority research themes to address the problem, based on analysing the state of knowledge.
This book is the first comprehensive volume on the "Nramp family," highlighting the physiological importance of Nramp proteins as metal transporters. The molecular knowledge of these membrane proteins is presented from an evolutionary perspective, considering Nramp cellular function and mechanism of transport in key model organisms. The pathological significance of Nramp genetic polymorphism is discussed with emphasis on metal homeostasis and microbial infection. The chapters were contributed by leading investigators, providing a timely state of the art book in this rapidly growing field. The Nramp Family will be useful to a broad community of scientists interested in metal transport and molecular biology. It will be of interest to the research audience in the broad fields of metal ions and molecular medicine.
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