This book is the first comprehensive volume on the "Nramp
family," highlighting the physiological importance of Nramp
proteins as metal transporters. The molecular knowledge of these
membrane proteins is presented from an evolutionary perspective,
considering Nramp cellular function and mechanism of transport in
key model organisms. The pathological significance of Nramp genetic
polymorphism is discussed with emphasis on metal homeostasis and
microbial infection. The chapters were contributed by leading
investigators, providing a timely state of the art book in this
rapidly growing field.
The Nramp Family will be useful to a broad community of
scientists interested in metal transport and molecular biology. It
will be of interest to the research audience in the broad fields of
metal ions and molecular medicine.
General
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