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This volume summarizes the proceedings of the fifth biennial Cancer
Teaching Symposium held on March 4 and 5, 1972 at the University of
Chicago Pritzker School of Medicine. The program was prepared by
Drs. MELVIN GRIEM, ELWOOD JENSEN, HAROLD SUTTON, JOHN ULTMANN, and
ROBERT WISSLER. The purpose of the symposium was to present the
current status of the challenging cancer problem, breast carcinoma,
to the staff and students of this medical center and to students
and in terested physicians from other institutions in the Chicago
area. In a fashion similar to the other teaching symposia held in
1964, 1966, 1968, . and 1970, this symposium attracted over 450
physicians and scientists. In the course of one and one half days
the audience had the opportunity to listen to 18 invited speakers
and to the lively discussions. The formal presentations are
recorded in these pages. This teaching symposium could not have
been undertaken without the faithful assistance of the program
committee, the cancer training grant education committee, the staff
who recorded and transcribed the proceedings, and the editorial
assistants. We wish to thank the following for their efforts: JULIE
KANT, Administrative Secre tary for the Clinical Cancer Training
Grant, as well as Dr. JAMES MARKS, MARGARET WOEHRLE, FRIEDA RANNEY,
and ROSIE BARTLETT. This symposium received financial support from
USPHS Clinical Cancer Train ing Grant 5T12 CA-08077-06 and from the
Chicago Tumor Institute. MELVIN L. GRIEM, M. D. ROBERT W. WISSLER,
Ph. D., M. D."
This volume summarizes the Proceedings of the fourth biennial
Cancer Teaching Symposium held on March 7 and 8, 1970, at the
University of Chicago Pritzker School of Medicine. The program was
prepared by Drs. LAWRENCE ALLEN, MELVIN GRIEM, WERNER KIRSTEN, LEON
JACOBSON, JOHN ULTMANN, ROBERT WISSLER, and STANLEY Y ACHNIN. The
purpose of the Symposium was to present current advances in the
area of lymphoma and leukemia to the staff and students of this
medical center and to students and interested physicians from other
institutions in the Chicago area. Like the other teaching symposia
held in 1964, 1966, and 1968, this Symposium attracted over 450
physicians and scientists. In the course of one and a half days the
audience had the opportunity to listen to the twenty-four invited
speakers and to lively discussions. The formal presentations as
well as discussions are recorded in these pages. This Teaching
Symposium could not have been undertaken without the faithful
assistance of the Program Committee, the Cancer Training Grant
Advisory Com mittee, the staff who recorded and transcribed the
Proceedings, and the editorial assistants. We wish to thank the
following for their efforts: DOROTHY A. WILLIS, Administrative
Secretary for Institutional Cancer Training Grant, Dr. ROBERT L.
HUNTER, Dr. ROBERT H. KIRSCHNER, Dr. ROBERT A. ORLANDO, Dr. STEPHEN
STRUM, RANDOLPH HUGHES, JULIA KANT, GEORGIA MOHR, TERRY PEARSON,
FRIEDA RANNEY, and CAROL REESE. This Symposium received financial
support from the Cancer Training Program Tt2 CA 08077-04 and The
Chicago Tumor Institute."
Even though numerous questions with regard to the pathogenesis of
athero sclerosis have not yet been answered, the accumulated
evidence indicates significant regression of lesions in
experimental animals. This is discussed extensively in this
monograph, as are the mechanisms involved in regression of lesions.
Whether human atherosclerosis has the potential for regression
appears to be the most important, but at the same time the most
difficult question to answer. Contrary to experimental
atherosclerosis in animals, which can be produced and which can
regress within a few months, human lesions in general develop
slowly over many years. Therefore, measures aimed at modifying this
process may also require many years to be successful. In addition,
repeated direct examination of lesions in the human is usually not
possible. Nevertheless, recent reports in patients with
hyperlipoproteinemias indicate that pronounced and maintained
control of hyperlipidemias may lead, even within months, to
regression as evidenced by angiography or sophisticated
measurements of peripheral circulation. The monograph is divided
into two sections. The first will deal with of lipid deposition in
the arterial wall, whether "atherogenesis" mechanisms or not there
is evidence of monoclonal origin of human atherosclerosis plaques,
cell culture and factors that stimulate smooth muscle
proliferation, and animal models of atherogenesis. This section is
concluded with a discussion of dietary factors other than lipids in
atherogenesis."
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