This issue of Clinics in Plastic Surgery, Guest Edited by Drs. Brian R. Gastman and Michael W. Neumeister, is dedicated to Melanoma. This issue is one of four selected each year. Articles in this issue include, but are not limited to: Melanoma risk factors and prevention, Biology and signaling pathways of melanoma, Immunobiology of melanoma, Clinical diagnosis and classification, Histopathologic and molecular diagnosis of melanoma, AJCC staging and other platforms to assess prognosis and risk, Current treatment guidelines of primary melanoma including wide excision and use of sentinel node biopsy, Dermatologic follow-up and assessment of suspicious lesions, Immunotherapy of melanoma, Targeted therapies for melanoma, Non-operative intra-tumoral therapies, Role of radiation for locoregional and distant metastatic melanoma, Adjuvant and neoadjuvant therapy for melanoma, Surgery of the nodal basins for trunk and extremity melanoma, Extirpative considerations of melanoma of the head and neck, Treatment of lentigo melanoma of the head and neck, Reconstructive considerations of melanoma of the head and neck, Melanoma of the hands and feet, Rare variants of melanoma, and Emerging therapies for melanoma.

The authors' aim in this book is to give a pedagogical introduction to the helicity method, illustrated by many examples, and to summarize some ten years of research on the subject. Only some degree of familiarity with Feynman diagrams and Dirac algebra is required from the reader. The book also provides an extensive list of helicity amplitudes and cross-sections for many of the most important QED and QCD processes at high energies, some being new and not available in the literature previously.