This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

A call to action to include marginalized, non-western communities in the continuously expanding digital revolution In the digital age, technology has shrunk the physical world into a "global village," where we all seem to be connected as an online community as information travels to the farthest reaches of the planet with the click of a mouse. Yet while we think of platforms such as Twitter and Facebook as open and accessible to all, in reality, these are commercial entities developed primarily by and for the Western world. Considering how new technologies increasingly shape labor, economics, and politics, these tools often reinforce the inequalities of globalization, rarely reflecting the perspectives of those at the bottom of the digital divide. This book asks us to re-consider 'whose global village' we are shaping with the digital technology revolution today. Sharing stories of collaboration with Native Americans in California and New Mexico, revolutionaries in Egypt, communities in rural India, and others across the world, Ramesh Srinivasan urges us to re-imagine what the Internet, mobile phones, or social media platforms may look like when considered from the perspective of diverse cultures. Such collaborations can pave the way for a people-first approach toward designing and working with new technology worldwide. Whose Global Village seeks to inspire professionals, activists, and scholars alike to think about technology in a way that embraces the realities of communities too often relegated to the margins. We can then start to visualize a world where technologies serve diverse communities rather than just the Western consumer.

How to repair the disconnect between designers and users, producers and consumers, and tech elites and the rest of us: toward a more democratic internet.In this provocative book, Ramesh Srinivasan describes the internet as both an enabler of frictionless efficiency and a dirty tangle of politics, economics, and other inefficient, inharmonious human activities. We may love the immediacy of Google search results, the convenience of buying from Amazon, and the elegance and power of our Apple devices, but it's a one-way, top-down process. We're not asked for our input, or our opinions--only for our data. The internet is brought to us by wealthy technologists in Silicon Valley and China. It's time, Srinivasan argues, that we think in terms beyond the Valley. Srinivasan focuses on the disconnection he sees between designers and users, producers and consumers, and tech elites and the rest of us. The recent Cambridge Analytica and Russian misinformation scandals exemplify the imbalance of a digital world that puts profits before inclusivity and democracy. In search of a more democratic internet, Srinivasan takes us to the mountains of Oaxaca, East and West Africa, China, Scandinavia, North America, and elsewhere, visiting the "design labs" of rural, low-income, and indigenous people around the world. He talks to a range of high-profile public figures--including Elizabeth Warren, David Axelrod, Eric Holder, Noam Chomsky, Lawrence Lessig, and the founders of Reddit, as well as community organizers, labor leaders, and human rights activists.. To make a better internet, Srinivasan says, we need a new ethic of diversity, openness, and inclusivity, empowering those now excluded from decisions about how technologies are designed, who profits from them, and who are surveilled and exploited by them.

A call to action to include marginalized, non-western communities in the continuously expanding digital revolution In the digital age, technology has shrunk the physical world into a "global village," where we all seem to be connected as an online community as information travels to the farthest reaches of the planet with the click of a mouse. Yet while we think of platforms such as Twitter and Facebook as open and accessible to all, in reality, these are commercial entities developed primarily by and for the Western world. Considering how new technologies increasingly shape labor, economics, and politics, these tools often reinforce the inequalities of globalization, rarely reflecting the perspectives of those at the bottom of the digital divide. This book asks us to re-consider 'whose global village' we are shaping with the digital technology revolution today. Sharing stories of collaboration with Native Americans in California and New Mexico, revolutionaries in Egypt, communities in rural India, and others across the world, Ramesh Srinivasan urges us to re-imagine what the Internet, mobile phones, or social media platforms may look like when considered from the perspective of diverse cultures. Such collaborations can pave the way for a people-first approach toward designing and working with new technology worldwide. Whose Global Village seeks to inspire professionals, activists, and scholars alike to think about technology in a way that embraces the realities of communities too often relegated to the margins. We can then start to visualize a world where technologies serve diverse communities rather than just the Western consumer.

Electroencephalography (EEG) is practiced by neurologists, cognitive neuroscientists, and others interested in functional brain imaging. Whether for clinical or experimental purposes, all studies share a common purpose-to relate scalp potentials to the underlying neurophysiology. Electrical potentials on the scalp exhibit spatial and temporal patterns that depend on the nature and location of the sources and the way that currents and fields spread through tissue. Because these dynamic patterns are correlated with behavior and cognition, EEG provides a "window on the mind," correlating physiology and psychology.
This classic and widely acclaimed text, originally published in 1981, filled the large gap between EEG and the physical sciences. It has now been brought completely up to date and will again serve as an invaluable resource for understanding the principles of electric fields in living tissue and for using hard science to study human consciousness and cognition. No comparable volume exists for it is no easy task to explain the problems of EEG in clear language, with mathematics presented mainly in appendices. Among the many topics covered by the Second Edition are micro and meso (intermediate scale) synaptic sources, electrode placement, choice of reference, volume conduction, power and coherence measures, projection of scalp potentials to dura surface, dynamic signatures of conscious experience, neural networks immersed in global fields of synaptic action, and physiological bases for brain source dynamics. The Second Edition is an invaluable resource for neurologists, neuroscientists (especially cognitive neuroscientists), biomedical engineers, and their students andtrainees. It will also appeal to physicists, mathematicians, computer scientists, psychiatrists, and industrial engineers interested in EEG.