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Marine Protected Areas: Science, Policy and Management addresses a
full spectrum of issues relating to Marine Protected Areas (MPAs)
not currently available in any other single volume. Chapters are
contributed by a wide range of working specialists who examine
conceptions and definitions of MPAs, progress on the implementation
of worldwide MPAs, policy and legal variations across MPAs, the
general importance of coastal communities in implementation, and
the future of MPAs. The book constructively elucidates conflicts,
issues, approaches and solutions in a way that creates a balanced
consideration of the nature of effective policy and management.
Those in theory, designation, implementation or management of MPAs,
from individuals, marine sector organizations, and university and
research center libraries will find it an important work.
This thorough volume explores recent advances that have
revolutionized the field of precision oncology. The chapters,
contributed by experts in the areas of cancer systems and
integrative biology, provide hands-on guidance toward developing
tools to monitor spatial and temporal changes in tumors, tracking
tumor markers in blood, and ultimately developing precision
medicine to combat cancer in real time. Written for the highly
successful Methods in Molecular Biology series, chapters include
the kind of detailed implementation advice that ensures successful
results. Authoritative and informative, Cancer Systems and
Integrative Biology serves as an invaluable resource for
researchers, pharmaceutical scientists, and oncologists interested
in expanding their knowledge base in the current developments in
cancer research.
This volume presents state-of-the-art information on each of the
arms of the unfolded protein response (UPR), how their
activation/repression are regulated, integrated, and coordinated,
how UPR components affect cancer cell biology and responsiveness to
therapeutic interventions, and how UPR components/activities offer
potentially novel targets for drug discovery, repurposing, and
development. The volume will provide the most recent information on
the signaling and regulation of the UPR, explore examples of how
the UPR and/or specific components contribute to cancer biology,
and identify and explore specific examples of potently new
actionable targets for drug discovery and development from within
the UPR and its regulation. Unique to the volume will be a specific
focus on the UPR and its role in cancer biology, as well as a
discussion of the role of the UPR in drug responses and resistance
in cancer.
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