The motivation for us to produce a treatise on regulation was mainly our convic tion that it would be fun, and at the same time productive, to approach the subject in a way that differs from that of other treatises. We had ourselves written reviews for various volumes over the years, most of them bringing together all possible facts relevant to a particular operon, virus, or biosynthetic system. And we were not convinced of the value of such reviews for anyone but the expert in the field reviewed. We thought it might be more interesting and more instructive-for both author and reader-to avoid reviewing topics that anyone scientist might work on, but instead to review the various parts of what many different scientists work on. Cutting across the traditional boundaries that have separated the subjects in past volumes on regulation is not an easy thing to do-not because it is difficult to think of what interesting topics should replace the old ones, but because it is difficult to find authors who possess sufficient breadth of knowledge and who are willing to write about areas outside those pursued in their own laboratories. For example, no one scientist works on suppression per se. He may study the structure of suppressor tRNAs in Escherichia coli, he may study phenotypic suppression of various characters in drosophila, he may study polarity in gene expression, and so on.

Evolutionary Multi-Objective Optimization is an expanding field of research. This book brings a collection of papers with some of the most recent advances in this field. The topic and content is currently very fashionable and has immense potential for practical applications and includes contributions from leading researchers in the field. Assembled in a compelling and well-organised fashion, Evolutionary Computation Based Multi-Criteria Optimization will prove beneficial for both academic and industrial scientists and engineers engaged in research and development and application of evolutionary algorithm based MCO. Packed with must-find information, this book is the first to comprehensively and clearly address the issue of evolutionary computation based MCO, and is an essential read for any researcher or practitioner of the technique.

Recovering Reason: Essays in Honor of Thomas L. Pangle is a collection of essays composed by students and friends of Thomas L. Pangle to honor his seminal work and outstanding guidance in the study of political philosophy. The contributors write in awareness that a loss of confidence in reason similar to the one we are witnessing today when the desirability and possibility of guiding our lives by the enduring, normative truths that reason attempts to discover had occurred at the time of Socrates, who realized that the existence of genuine limits to what is knowable by reason opened up the possibility that our world, instead of having the kind of intelligible necessities that science seeks to uncover, could be the work of mysterious, creative gods or god as devoutly religious citizens claimed it to be. His grasp of this great difficulty led him and his students ancient and medieval to attempt to ground the life of reason by means of a pre-philosophic, preliminary investigation of political-moral questions. Modern political philosophers later attempted to ground the life of reason in a considerably different, 'enlightening' way. These essays examine both of these attempts to answer the question of the right life for human beings, as those attempts are introduced and elaborated in the work of thinkers from Homer and Thucydides to Nietzsche and Charles Taylor. The volume is divided into five parts. The essays in Part I examine the moral-political problems through which Socrates came to ground the philosophic life as those problems first appeared in earlier, pre-Socratic writers. Part II explores those problems in their Platonic and Aristotelian presentations, and in the work of two medieval thinkers. Part III addresses the thought of Leo Strauss, the thinker upon whose work the recovery of both ancient and modern political philosophy in our day has been made possible. Part IV explicates the writings of modern political philosophers and thinkers with a view to uncovering their alternative approach to science and political life. The volume concludes in Part V with essays addressing contemporary problems enlightened by the study of political philosophy.

Recovering Reason: Essays in Honor of Thomas L. Pangle is a collection of essays composed by students and friends of Thomas L. Pangle to honor his seminal work and outstanding guidance in the study of political philosophy. The contributors write in awareness that a loss of confidence in reason similar to the one we are witnessing today when the desirability and possibility of guiding our lives by the enduring, normative truths that reason attempts to discover had occurred at the time of Socrates, who realized that the existence of genuine limits to what is knowable by reason opened up the possibility that our world, instead of having the kind of intelligible necessities that science seeks to uncover, could be the work of mysterious, creative gods or god as devoutly religious citizens claimed it to be. His grasp of this great difficulty led him and his students ancient and medieval to attempt to ground the life of reason by means of a pre-philosophic, preliminary investigation of political-moral questions. Modern political philosophers later attempted to ground the life of reason in a considerably different, "enlightening" way. These essays examine both of these attempts to answer the question of the right life for human beings, as those attempts are introduced and elaborated in the work of thinkers from Homer and Thucydides to Nietzsche and Charles Taylor. The volume is divided into five parts. The essays in Part I examine the moral-political problems through which Socrates came to ground the philosophic life as those problems first appeared in earlier, pre-Socratic writers. Part II explores those problems in their Platonic and Aristotelian presentations, and in the work of two medieval thinkers. Part III addresses the thought of Leo Strauss, the thinker upon whose work the recovery of both ancient and modern political philosophy in our day has been made possible. Part IV explicates the writings of modern political philosophers and thinkers with a view to uncovering their alternative approach

Evolutionary Multiobjective Optimization is a rare collection of the latest state-of-the-art theoretical research, design challenges and applications in the field of multiobjective optimization paradigms using evolutionary algorithms. It includes two introductory chapters giving all the fundamental definitions, several complex test functions and a practical problem involving the multiobjective optimization of space structures under static and seismic loading conditions used to illustrate the various multiobjective optimization concepts.

Important features include:

• Detailed overview of all the multiobjective optimization paradigms using evolutionary algorithms
• Excellent coverage of timely, advanced multiobjective optimization topics
• State-of-the-art theoretical research and application developments
• Chapters authored by pioneers in the field

Academics and industrial scientists as well as engineers engaged in research, development and application of evolutionary algorithm based Multiobjective Optimization will find the comprehensive coverage of this book invaluable.

The Vaccines For Children Program (VFC) was the Clinton administration' first shot in the battle to pass the Health Security Act. Envisioned as a symbol of President Clinton's commitment to social change, the program was designed to be a single-payer system for childhood vaccines, covering everyone up to the age of eighteen. Today the program is in disarray.

This volume is a collection of essays by various contributors in honor of the late Laurence Berns, Richard Hammond Elliot Tutor Emeritus at St. John's College, Annapolis. The essays address the literary, political, theological, and philosophical themes of his life's work as a scholar, teacher, and constant companion of the "great books." Included are essays interpreting biblical books, as well as books by Homer, Herodotus, Aeschylus, Sophocles, Euripides, Plato, Virgil, Dante, Spinoza, Milton, Rousseau, Darwin, Dostoevsky, Nietzsche, Camus, and H.G. Wells. Like their honoree, the essayists aim at understanding such books as their authors wished them to be understood-for the light they shed on universal and timeless questions about God, nature, and human life which animated the authors themselves and which they saw fit to share, elegantly and eloquently, with thoughtful readers. Each essay is, in its way, a model of how to read and reflect on the writings of the great authors.