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Hydrogels are a particular class of compounds of which the major
constituent is wa- ter. In fact, water is present in the hydrogel
up to 90% and is contained in a scaffold which is generally
polymeric and obviously hydrophilic. As a result, hydrogels re-
semble each other even though obtained from different polymers.
Nevertheless, the polymeric matrix gives particular characteristics
to the hydrogel leading to applica- tions in different fields.
Water is the main element of the human body, thus hydrogels are
excellent struc- tures to favourably shelter proteins, cells etc. ,
without altering their characteristics and properties. This is why
hydrogels are mainly designed and synthesized for their usein
thebiologicalfield;hence the name biohydrogels. Their
propertiespoint totheir use as scaffolds for stem cells which has
turned out to be a very promising technique for tissue and organ
regeneration. For this reason their investigation falls within the
Biomaterials Science. Paradoxically, the conceptual simplicity of
hydrogelsupto nowhas led to a super- ficialstudy of their
chemistry, chemical physics and mechanics preventing their wider
application in the human body due to a lack of knowledge of
biological component interactions. For example, it is not clear,
yet, how to store hydrogels without alter- ing their
characteristics. In fact, hydrogels re-hydrated after
lyophylization or oven drying, generally show corrupted properties
once swollen in water, in comparison with their native
counterparts.
Integrated Biomaterials Science provides an intriguing insight into
the world of biomaterials. It explores the materials and technology
which have brought advances in new biomaterials, highlighting the
way in which modern biology and medicine are synergistically linked
to other key scientific disciplines-physics, chemistry, and
engineering. In doing so, Integrated Biomaterials Science contains
chapters on tissue engineering and gene therapy, standards and
parameters of biomaterials, applications and interactions within
the industrial world, as well as potential aspects of patent
regulations.
Integrated Biomaterials Science serves as a comprehensive guide to
understanding this dynamic field, yet is designed so that chapters
may be read and understood independently, depending on the needs of
the reader. Integrated Biomaterials Science is attractive to a
broad audience interested in a deeper understanding of this
evolving field, and serves as a key resource for researchers and
students of biomaterials courses, providing all with an opportunity
to probe further.
Hydrogels are a particular class of compounds of which the major
constituent is wa- ter. In fact, water is present in the hydrogel
up to 90% and is contained in a scaffold which is generally
polymeric and obviously hydrophilic. As a result, hydrogels re-
semble each other even though obtained from different polymers.
Nevertheless, the polymeric matrix gives particular characteristics
to the hydrogel leading to applica- tions in different fields.
Water is the main element of the human body, thus hydrogels are
excellent struc- tures to favourably shelter proteins, cells etc. ,
without altering their characteristics and properties. This is why
hydrogels are mainly designed and synthesized for their usein
thebiologicalfield;hence the name biohydrogels. Their
propertiespoint totheir use as scaffolds for stem cells which has
turned out to be a very promising technique for tissue and organ
regeneration. For this reason their investigation falls within the
Biomaterials Science. Paradoxically, the conceptual simplicity of
hydrogelsupto nowhas led to a super- ficialstudy of their
chemistry, chemical physics and mechanics preventing their wider
application in the human body due to a lack of knowledge of
biological component interactions. For example, it is not clear,
yet, how to store hydrogels without alter- ing their
characteristics. In fact, hydrogels re-hydrated after
lyophylization or oven drying, generally show corrupted properties
once swollen in water, in comparison with their native
counterparts.
Integrated Biomaterials Science provides an intriguing insight into
the world of biomaterials. It explores the materials and technology
which have brought advances in new biomaterials, highlighting the
way in which modern biology and medicine are synergistically linked
to other key scientific disciplines-physics, chemistry, and
engineering. In doing so, Integrated Biomaterials Science contains
chapters on tissue engineering and gene therapy, standards and
parameters of biomaterials, applications and interactions within
the industrial world, as well as potential aspects of patent
regulations. Integrated Biomaterials Science serves as a
comprehensive guide to understanding this dynamic field, yet is
designed so that chapters may be read and understood independently,
depending on the needs of the reader. Integrated Biomaterials
Science is attractive to a broad audience interested in a deeper
understanding of this evolving field, and serves as a key resource
for researchers and students of biomaterials courses, providing all
with an opportunity to probe further.
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