First published in 1966, Thompson and Thompson Genetics and Genomics in Medicine has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over. Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveries-such as the functional roles of non-coding RNAs, chromatin regulation and epigenetics-latest technologies, and new diagnoses they are enabling. Under an expanded title, this ninth edition has been completely revised by a new editorial team overseeing a large cadre of contributing authors. Support groups have also assisted to update illustrations featuring beautiful images of those living with genetic conditions. Comprehensive coverage of: genomes in biology and medicine; copy number and structural genomic variation; novel discoveries; latest technology; and new genetic diagnoses Over 40 clinical case studies, capturing the latest challenges of variable expression, pleiotropy, and complex disorders through new diagnostic strategies Full-color text, illustrations, updated line diagrams, and clinical photos End-of-chapter questions and comprehensive answers to challenge the reader to consolidate the material into practice and prepare for examinations USMLE-style and multiple choice questions available as part of the eBook An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud Updated and new clinical cases, supported with photography by the not-for-profit organization, Positive Exposure New content on growing role of sequencing and novel functional assays in diagnosis and screening of genetic conditions New chapter on Epigenetics Clearer and more precise terminology, in response to contemporary and evolving guidelines New sections describing the use (and need for) genetic information from diverse populations, including unique indigenous and founder populations, for diagnosis and management.

High Quality Content by WIKIPEDIA articles Bog bodies, which are also known as bog people, are the naturally preserved human corpses found in the sphagnum bogs in Northern Europe. Unlike most ancient human remains, bog bodies have retained their skin and internal organs due to the unusual conditions of the surrounding area. These conditions include highly acidic water, low temperature, and a lack of oxygen, combining to preserve but severely tan their skin. Despite the fact that their skin is preserved, their bones are generally not, as the acid in the peat dissolves the calcium phosphate of bone.

High Quality Content by WIKIPEDIA articles Cocoa butter, also called theobroma oil, is a pale-yellow, pure edible vegetable fat extracted from the cocoa bean. It is used to make chocolate, biscuits, and baked goods, as well as some pharmaceuticals, ointments, and toiletries. Cocoa butter has a mild chocolate flavor and aroma.

High Quality Content by WIKIPEDIA articles IsaacI Komnenos (or Comnenus) (Greek: A', IsaakiosI Komn nos) (c. 1007 - 1061) was Byzantine Emperor from 1057 to 1059, and the first reigning member of the Komnenos dynasty. His brief reign saw an attempt to restore the Byzantine Empire's military capability and reputation.

High Quality Content by WIKIPEDIA articles Orlando Figes (/ fa d i z/; born 20 November 1959) is a British historian of Russia, and Professor of History at Birkbeck, University of London.

High Quality Content by WIKIPEDIA articles Diane Henry (born March 1, 1982, Euless, Texas) is an American model most known for coming in third on Big Brother 5, a reality TV show broadcast by CBS in 2004. At the time of the show, CBS described her as a 22-year old cocktail waitress from Burlington, Kentucky.

High Quality Content by WIKIPEDIA articles The Princess Bride is a 1973 fantasy novel written by William Goldman. It was originally published in the United States by Harcourt Brace, while in the UK it is/was published by Bloomsbury Publishing.

High Quality Content by WIKIPEDIA articles Sonic Unleashed (known as Sonic World Adventure (, Sonikku W rudo Adobench ?) in Japan), is a video game and the 11th installment in the Sonic the Hedgehog series developed by Sonic Team and published by Sega for multiple platforms in 2008. The game follows Sonic the Hedgehog as he attempts to restore the world to normal after his nemesis, Doctor Eggman, splits the world into pieces, as well as his struggles with his new beast form, Sonic the Werehog. Gameplay features two distinct styles, with each being played either during daytime or night-time. Daytime stages incorporate Sonic's traditional platforming and trademark speed, with a combination of behind-the-back third-person viewpoints and 2D side-scroller platforming; gameplay seamlessly transitions between these two views. Night-time levels see Sonic transform into the Werehog; gameplay slows down to accommodate greater platform play, and involves combat against waves of enemies using the Werehog's brute strength.

High Quality Content by WIKIPEDIA articles Painted Dreams is an American radio soap opera that was the first daytime radio soap opera program in the United States. It premiered October 20, 1930 and last aired in July, 1943.

High Quality Content by WIKIPEDIA articles Dr. Valerie Virginia Hunt (born July 22, 1916) is a scientist, author, lecturer and Professor Emeritus of Physiological Science at the University of California, Los Angeles. Hunt was born in 1916 in Larwill, Indiana. She retired from the UCLA in 1980. Her work influenced the development of dance/movement therapy.

High Quality Content by WIKIPEDIA articles Yankee Girl is a superhero who appears in the Femforce comics published by AC Comics. The character is based on an obscure Golden Age superheroine, who appeared in one issue of Dynamic Comics #23 (November 1947), published by Harry "A" Chesler.

High Quality Content by WIKIPEDIA articles Sir Arthur Seymour Sullivan MVO (13 May 1842 - 22 November 1900) was an English composer of Irish and Italian ancestry. He is best known for his series of 14 operatic collaborations with the dramatist W. S. Gilbert, including such enduring works as H.M.S. Pinafore, The Pirates of Penzance and The Mikado. Sullivan composed 23 operas, 13 major orchestral works, eight choral works and oratorios, two ballets, incidental music to several plays, and numerous hymns and other church pieces, songs, and piano and chamber pieces. The best known of his hymns and songs include "Onward Christian Soldiers" and "The Lost Chord."

High Quality Content by WIKIPEDIA articles The Pace Gallery is a contemporary and modern art gallery founded by Arne Glimcher in Boston 1960 as The Pace Gallery. The gallery moved to Manhattan in 1963 and from 1993 to 2010 operated jointly with Wildenstein Co. as PaceWildenstein. There are three locations in Manhattan (one in Midtown at 32 East 57th St and two in Chelsea) and one in Beijing, China. PaceWildenstein was the first major Manhattan art gallery to open a space in Beijing. In January 2009, PaceWildenstein announced plans for an independent publishing company called Artifex press, dedicated to the creation of online artists' catalogues raisonnees.

High Quality Content by WIKIPEDIA articles The Subtle Knife, the second novel in the book His Dark Materials series, was written by English novelist Philip Pullman and published in 1997. The novel continues the adventures of Lyra Belacqua as she investigates the mysterious Dust phenomenon and searches for her father. Will Parry is introduced as a companion to Lyra, and together they explore the new realms to which they have both been introduced.

High Quality Content by WIKIPEDIA articles Nanny 911 is a reality television show in the United States, which originally aired on FOX (and airs in the UK on ITV2, whose sister company, Granada America, produces the show).

High Quality Content by WIKIPEDIA articles Horrible Histories is a series of illustrated history books published in the United Kingdom by Scholastic. They are designed to engage children in history by concentrating on the unusual, gory, or unpleasant. The series has proved exceptionally successful in commercial terms. The books are written by Terry Deary, Peter Hepplewhite and Neil Tonge and illustrated by Martin Brown, Mike Phillips and Philip Reeve.

High Quality Content by WIKIPEDIA articles Arthur and the Invisibles (Arthur and the Minimoys in non-English-speaking territories - Arthur et les Minimoys in French-speaking countries) is a French/American part-animated, part-live action feature film adaptation of the 2002 children's book Arthur et les minimoys / Arthur and the Minimoys, and the 2003 sequel Arthur et la cite interdite / Arthur and the Forbidden City, written by filmmaker Luc Besson, who also directed the film. It premiered in limited release in France on November 29, 2006, and received wide releases in a number of countries in the following weeks. In the United States, it opened on December 29, 2006, for one week in Los Angeles, California, with a wider release on January 12, 2007 and it was released in the United Kingdom on February 2, 2007. The film was MGM's first theatrically released animated film since 1996's All Dogs Go to Heaven 2. MGM's rights were dissolved when the movie hit theaters in December 29, 2006.

High Quality Content by WIKIPEDIA articles Dita Von Teese (born Heather Renee Sweet on September 28, 1972) is an American burlesque dancer, model, costume designer, author and actress.

High Quality Content by WIKIPEDIA articles Yash Raj Films USA, Inc. is an American film distribution company based in New York. It is a fully owned subsidiary of Indian Film Studio Yash Raj Films Pvt. Ltd..

High Quality Content by WIKIPEDIA articles The Paradox of Choice - Why More Is Less is a 2004 book by American psychologist Barry Schwartz. In the book, Schwartz argues that eliminating consumer choices can greatly reduce anxiety for shoppers. This same issue was first proposed by Jose Ortega y Gasset in Chapter 4 of his book The Revolt of the Masses.

High Quality Content by WIKIPEDIA articles The Amber Spyglass is the third and final novel in the His Dark Materials series, written by English author Philip Pullman, and published in 2000.

High Quality Content by WIKIPEDIA articles The music of the video game Final Fantasy IX was composed by regular series composer Nobuo Uematsu. It was his last exclusive Final Fantasy score. The Final Fantasy IX Original Soundtrack, a compilation of all music in the game, was originally released on four Compact Discs by DigiCube in 2000, and was re-released by Square Enix in 2004. A Best Of and arranged soundtrack album of musical tracks from the game entitled Final Fantasy IX: Uematsu's Best Selection was released in 2000 by Tokyopop Soundtrax. Final Fantasy IX Original Soundtrack PLUS, an album of music from the game's full motion videos and extra tracks, was released by DigiCube in 2000 and re-released in 2004, and a collection of piano arrangements of songs from the original soundtrack composed by Shir Hamaguchi and performed by Louis Leerink was released as Piano Collections Final Fantasy IX in 2001.