If Edward Everett is remembered at all today, it is as the orator who gave the other speech at Gettysburg, Pennsylvania on November 19, 1863. Ironically, Everett's oration, which was given wide coverage in contemporary newspapers, was recognized as both epideictic and argumentative. Everett defended the Union cause, whereas Lincoln's speech was strictly ceremonial. A second irony that attends Everett's oratorical career is that his countrymen believed him to be one of the great orators of the time, the undisputed master of ceremonial address. In this first new study of Edward Everett's oratory, author Ronald Reid addresses the historical and oratorical paradoxes that have influenced perceptions of Everett's career. Reid reconstitutes the role of epideictic rhetoric in the United States from the end of the Revolutionary War to the eve of the Civil War and reinstates Everett in the pantheon of great American orators. He demonstrates why Everett fell into virtual obscurity and treats the reader to a penetrating analysis of the role of public persuasion in the United States during a critical period in its history. In Edward Everett: Unionist Orator Reid effectively restores Everett to his rightful rostrum in the unfolding national drama from the 1820s to the 1860s, providing a sweeping story of America's golden age of oratory in the process. The book opens with a discussion of the influence of Everett's eighteenth-century heritage on his desire to save the Union at all costs. The author shows how the seeds of Everett's Unionism were starting to sprout in his literary and theological speeches and writings, and how he developed the rhetorical methods that he would use throughout his career.Next, Reid deals with Everett's oratory during his years of service, first as a congressman and then as governor of Massachusetts. Here he discusses Everett's increasing concern about the divisiveness of the partisan and sectional causes he espoused. Chapters three and four deal with Everett's modification of his earlier Unionist strategies in an effort to deal with increasing sectionalism and preserve the United States. In conclusion, Reid reviews Everett's oratory, speculating about the role of epideictic oratory in general in maintaining, or failing to maintain, social unity. Sample speeches complete the work, which include a partial text of one of Everett's congressional speeches, a 4th of July oration, his "Character of Washington," and a partial text of Everett's Gettysburg address.

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication. Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry, protein sequence, and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemis

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.
Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication.
Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis
discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability
analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology
examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods
highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry
demonstrates uses of unnatural mutagenesis and combinatorial chemistry
explores mass spectrometry, protein sequence, and carbohydrate analysis
illustrates bioassays and other new functional analysis methods
surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR)
addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells
reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering
and more
Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.