Enzymes are bio-catalysts which effect transformation of substrates to products with high specificity. The usage of enzymes in domestic and industrial applications is well known and has been well documented since the early history of civilization. With the advances in understanding of enzymology, usage of enzymes in industrial and biotechnological pro cesses and molecular medicine has proliferated. One of the key factors in the widespread application of enzymes in modern technologies is the development of enzyme immobilization tech niques, which overcome certain practical, functional and economic con straints. Many natural enzymes can be stabilized by immobilization on solid matrices, with most of the activity retained, for a variety of applica tions. An important application of immobilized enzymes is in liquid chromatography. In the last decade, post-column enzyme detection has become established as an important discipline in liquid chromatography. The new detection approach offers more sensitive and specific ways for measuring major classes of biomolecules. Reactors are fabricated by packing the immobilized enzymes into small columns, which can be placed immediately after an HPLC column."

An accessible guide to an increasingly complex subject, Entrepreneurial Finance: Concepts and Cases demonstrates how to address often- overlooked financial issues from the entrepreneur's standpoint, including challenges faced by start-ups and small businesses. This new edition retains the original's structure, around seven modules or building blocks designed to be taught across a full semester with natural break points built into each chapter within the modules. The building blocks present macro- concepts which are explored in greater detail in each of the chapters. Each concept is illustrated by a short case and followed by thoughtful questions to enhance learning. The cases are new or fully updated for the second edition, and deal with real companies, real problems, and currently unfolding issues. A new chapter on business models includes coverage of social ventures, and the chapters on forms of business ownership and financing have been expanded. Upper- level undergraduate students of entrepreneurship will appreciate the book's practical approach and engaging tone, along with the hands- on cases and exercises that help students to break down complex concepts. Online resources for instructors include a case teaching manual, lecture slides, test bank, and interactive exercises.

This book is a revision of my Ph. D. thesis dissertation submitted to Carnegie Mellon University in 1987. It documents the research and results of the compiler technology developed for the Warp machine. Warp is a systolic array built out of custom, high-performance processors, each of which can execute up to 10 million floating-point operations per second (10 MFLOPS). Under the direction of H. T. Kung, the Warp machine matured from an academic, experimental prototype to a commercial product of General Electric. The Warp machine demonstrated that the scalable architecture of high-peiformance, programmable systolic arrays represents a practical, cost-effective solu tion to the present and future computation-intensive applications. The success of Warp led to the follow-on iWarp project, a joint project with Intel, to develop a single-chip 20 MFLOPS processor. The availability of the highly integrated iWarp processor will have a significant impact on parallel computing. One of the major challenges in the development of Warp was to build an optimizing compiler for the machine. First, the processors in the xx A Systolic Array Optimizing Compiler array cooperate at a fine granularity of parallelism, interaction between processors must be considered in the generation of code for individual processors. Second, the individual processors themselves derive their performance from a VLIW (Very Long Instruction Word) instruction set and a high degree of internal pipelining and parallelism. The compiler contains optimizations pertaining to the array level of parallelism, as well as optimizations for the individual VLIW processors."

This book is written with the belief that classical mechanics, as a theoretical discipline, possesses an inherent beauty, depth, and richness that far transcends its immediate applications in mechanical systems. These properties are manifested, by and large, through the coherence and elegance of the mathematical structure underlying the discipline, and are eminently worthy of being communicated to physics students at the earliest stage possible. This volume is therefore addressed mainly to advanced undergraduate and beginning graduate physics students who are interested in the application of modern mathematical methods in classical mechanics, in particular, those derived from the fields of topology and differential geometry, and also to the occasional mathematics student who is interested in important physics applications of these areas of mathematics. Its main purpose is to offer an introductory and broad glimpse of the majestic edifice of the mathematical theory of classical dynamics, not only in the time-honored analytical tradition of Newton, Laplace, Lagrange, Hamilton, Jacobi, and Whittaker, but also the more topological/geometrical one established by Poincare, and enriched by Birkhoff, Lyapunov, Smale, Siegel, Kolmogorov, Arnold, and Moser (as well as many others).

This book is a translation of an authoritative introductory text based on a lecture series delivered by the renowned differential geometer, Professor S S Chern in Beijing University in 1980. The original Chinese text, authored by Professor Chern and Professor Wei-Huan Chen, was a unique contribution to the mathematics literature, combining simplicity and economy of approach with depth of contents. The present translation is aimed at a wide audience, including (but not limited to) advanced undergraduate and graduate students in mathematics, as well as physicists interested in the diverse applications of differential geometry to physics. In addition to a thorough treatment of the fundamentals of manifold theory, exterior algebra, the exterior calculus, connections on fiber bundles, Riemannian geometry, Lie groups and moving frames, and complex manifolds (with a succinct introduction to the theory of Chern classes), and an appendix on the relationship between differential geometry and theoretical physics, this book includes a new chapter on Finsler geometry and a new appendix on the history and recent developments of differential geometry, the latter prepared specially for this edition by Professor Chern to bring the text into perspectives.

This textbook is mainly for physics students at the advanced undergraduate and beginning graduate levels, especially those with a theoretical inclination. Its chief purpose is to give a systematic introduction to the main ingredients of the fundamentals of quantum theory, with special emphasis on those aspects of group theory (spacetime and permutational symmetries and group representations) and differential geometry (geometrical phases, topological quantum numbers, and Chern-Simons Theory) that are relevant in modern developments of the subject. It will provide students with an overview of key elements of the theory, as well as a solid preparation in calculational techniques.

This book is a translation of an authoritative introductory text based on a lecture series delivered by the renowned differential geometer, Professor S S Chern in Beijing University in 1980. The original Chinese text, authored by Professor Chern and Professor Wei-Huan Chen, was a unique contribution to the mathematics literature, combining simplicity and economy of approach with depth of contents. The present translation is aimed at a wide audience, including (but not limited to) advanced undergraduate and graduate students in mathematics, as well as physicists interested in the diverse applications of differential geometry to physics. In addition to a thorough treatment of the fundamentals of manifold theory, exterior algebra, the exterior calculus, connections on fiber bundles, Riemannian geometry, Lie groups and moving frames, and complex manifolds (with a succinct introduction to the theory of Chern classes), and an appendix on the relationship between differential geometry and theoretical physics, this book includes a new chapter on Finsler geometry and a new appendix on the history and recent developments of differential geometry, the latter prepared specially for this edition by Professor Chern to bring the text into perspectives.

This book is a revision of my Ph. D. thesis dissertation submitted to Carnegie Mellon University in 1987. It documents the research and results of the compiler technology developed for the Warp machine. Warp is a systolic array built out of custom, high-performance processors, each of which can execute up to 10 million floating-point operations per second (10 MFLOPS). Under the direction of H. T. Kung, the Warp machine matured from an academic, experimental prototype to a commercial product of General Electric. The Warp machine demonstrated that the scalable architecture of high-peiformance, programmable systolic arrays represents a practical, cost-effective solu tion to the present and future computation-intensive applications. The success of Warp led to the follow-on iWarp project, a joint project with Intel, to develop a single-chip 20 MFLOPS processor. The availability of the highly integrated iWarp processor will have a significant impact on parallel computing. One of the major challenges in the development of Warp was to build an optimizing compiler for the machine. First, the processors in the xx A Systolic Array Optimizing Compiler array cooperate at a fine granularity of parallelism, interaction between processors must be considered in the generation of code for individual processors. Second, the individual processors themselves derive their performance from a VLIW (Very Long Instruction Word) instruction set and a high degree of internal pipelining and parallelism. The compiler contains optimizations pertaining to the array level of parallelism, as well as optimizations for the individual VLIW processors."

An accessible guide to an increasingly complex subject, Entrepreneurial Finance: Concepts and Cases demonstrates how to address often- overlooked financial issues from the entrepreneur's standpoint, including challenges faced by start-ups and small businesses. This new edition retains the original's structure, around seven modules or building blocks designed to be taught across a full semester with natural break points built into each chapter within the modules. The building blocks present macro- concepts which are explored in greater detail in each of the chapters. Each concept is illustrated by a short case and followed by thoughtful questions to enhance learning. The cases are new or fully updated for the second edition, and deal with real companies, real problems, and currently unfolding issues. A new chapter on business models includes coverage of social ventures, and the chapters on forms of business ownership and financing have been expanded. Upper- level undergraduate students of entrepreneurship will appreciate the book's practical approach and engaging tone, along with the hands- on cases and exercises that help students to break down complex concepts. Online resources for instructors include a case teaching manual, lecture slides, test bank, and interactive exercises.

Enzymes are bio-catalysts which effect transformation of substrates to products with high specificity. The usage of enzymes in domestic and industrial applications is well known and has been well documented since the early history of civilization. With the advances in understanding of enzymology, usage of enzymes in industrial and biotechnological pro cesses and molecular medicine has proliferated. One of the key factors in the widespread application of enzymes in modern technologies is the development of enzyme immobilization tech niques, which overcome certain practical, functional and economic con straints. Many natural enzymes can be stabilized by immobilization on solid matrices, with most of the activity retained, for a variety of applica tions. An important application of immobilized enzymes is in liquid chromatography. In the last decade, post-column enzyme detection has become established as an important discipline in liquid chromatography. The new detection approach offers more sensitive and specific ways for measuring major classes of biomolecules. Reactors are fabricated by packing the immobilized enzymes into small columns, which can be placed immediately after an HPLC column."