Uncontrolled environmental pollution, poor sanitary conditions, alcohol intoxication and indiscriminate use of potent drugs predispose liver to a vast array of disorders. Asthma is one of the most common disorders encountered in clinical medicine in both children and adults characterized by inflammation of the airway that is central to airway dysfunction. Effect of ethanol and aqoues extract of the leaves of Acalypha indica (Euphorbiaceae) was investigated against carbon tetra chloride-induced hepatic damage and Bronchodilator activity . carbon tetra chloride at the rate of 1 ml/kg produced liver damage in rats as manifested by the significant (P>0.001) rise in serum levels of AST, ALT, ALP compared to respective control values. Treatment of animals with the plant extract (200 and 400 mg/kg) orally once daily for 7 days prevented (P>0.01) the carbon tetra chloride -induced rise in serum transaminases (AST and ALT) and ALP. Bronchodilator activity studied on the spasmolytic activity on guinea pig isolated tracheal chain and Milk induced Eosinophillia and leukocytosis in mice. These results suggest that aqueous extract of the Acalypha indica Linn. has prove bronchodilating activity

Lung is the respiratory machinery of the body, which plays an outstanding array of critical functions in sustenance of the body. It's often affected by a multitude of drugs, all of which rest a burden on this vital organ that can culminate in various lung ailments. The most frequent and imperative obstacle in the bleomycin therapy is the Pulmonary toxicity. Pulmonary fibrosis (pneumopathy) is characterized by an increase in lung matrix and alterations in the numbers and spatial relationships of lung parenchymal cells. The increase in matrix results from a proliferation and activation of fibroblasts with increased production and deposition of matrix macromolecules at sites of lung injury. In this context, phyllanthus acidus is well known for its exploitation as an indigenous remedy in many lung, liver ailments. Thus, the present study was embarked upon in an endeavor to explore the salubrious role of phyllanthus acidus against the pulmonary repercussions provoked by bleomycin in a rat model.In this present study clearly suggest that the administration of Phyanthus acidus cure the Bleomycin induced pulmonary fibrosis.