|
Showing 1 - 10 of
10 matches in All Departments
|
Aquaporins, Volume 51 (Hardcover)
Dale J. Benos, Sidney A. Simon; Volume editing by Stefan Hohmann, Peter Agre, Soren Nielsen
|
R4,599
Discovery Miles 45 990
|
Ships in 12 - 17 working days
|
Aquaporins summarizes the present knowledge in this expanding field
of research, starting with the structural analysis of water channel
proteins. Subsequent chapters begin with mammalian aquaporins,
examining physiology and pathophysiology, analysis of knock-out
model animals, and the regulation of aquaporin function. Also
covered is the distribution and regulation of aquaporins in plants
and the function of water and glycerol channels in microbial
systems.
Key Features
* Comprehensive treatment of a topical research field
* Authored by world leaders in the field
* Covers structural biology and physiology
* Covers different experimental and biological systems
* Chapters on plant and microbial systems
* Extensive treatment of mammalian physiology and
pathophysiology
* Structural analysis excellently illustrated
Mechanisms of Taste Transduction introduces a number of topics
essential to a complete understanding of taste. These topics range
from the control of food intake to the biophysical mechanisms of
transduction and the design of food flavors in the food industry.
The responses and organization of special sensory pathways are
described in regard to their development, morphology, composition,
electrophysiological and biochemical responses. Details are
presented at several levels to appeal to researchers in molecular
biology, membrane biophysics, human psychophysics, neuroanatomy,
and chemistry. Current research is described in the context of what
preceding studies have revealed, and the chapter authors are among
today's most active and highly respected researchers in the field
of chemical senses.
Written by world experts in the field of neuronal chemoreception, Methods in Chemosensory Research describes new molecular, electrophysiological, genetic, behavioral, psychophysical, and imaging techniques that have recently been adapted to investigate the basic neuronal mechanisms underlying chemoreception: taste, olfaction and chemical-induced irritation. This unique book includes a wide variety of new and innovative imaging methods, electrophysiological methods, methods to investigate development, and various aspects of behavioral testing.
Covering the entire spectrum of chemoreception, each section not only describes what information can be obtained by using each method, but also shows how to apply each method to obtain reliable results. The book presents a comprehensive view of how the brain uses information about chemical stimuli that interact with receptors in the nose and tongue. Methods in Chemosensory Research gives you the new tools to learn how chemicals affect activity from the genetic to the behavioral levels.
This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.
Mechanisms of Taste Transduction introduces a number of topics
essential to a complete understanding of taste. These topics range
from the control of food intake to the biophysical mechanisms of
transduction and the design of food flavors in the food industry.
The responses and organization of special sensory pathways are
described in regard to their development, morphology, composition,
electrophysiological and biochemical responses. Details are
presented at several levels to appeal to researchers in molecular
biology, membrane biophysics, human psychophysics, neuroanatomy,
and chemistry. Current research is described in the context of what
preceding studies have revealed, and the chapter authors are among
today's most active and highly respected researchers in the field
of chemical senses.
DESCRIPTION:
Current Topics in Membranes provides a systematic, comprehensive,
and rigorous approach to specific topics relevant to the study of
cellular membranes. Each volume is a guest edited compendium of
membrane biology. Articles in this volume discuss ion
transport;
ocular aquaporins and aqueous humor dynamics;
the role of Ggap junction channels in the ciliary body secretory
epithelium; regional dependence of inflow; functional modulators
linking Iinflow with outflow of aqueous humor; aqueous humor
outflow resistance; aqueous humor dynamics; the effects of
circulatory events on
aqueous humor inflow and intraocular pressure; retinal ganglion
cells and glaucoma; what functional genomics is teaching us about
intraocular pressure regulation and glaucoma;
molecular approaches to glaucoma; outflow signaling mechanisms and
new therapeutic strategies for the control of intraocular pressure.
*Guest edited by cell membrane experts
*Dynamic and thorough coverage of all aspects of the aqueous humor
from inflow to outflow
*Provides the latest teachings on genomics and glaucoma
*Highlights new therapeutic strategies for the control of
intraocular pressure
"Current Topics in Membranes" provides a systematic, comprehensive,
and rigorous approach to specific topics relevant to the study of
cellular membranes. Each volume is a guest edited compendium of
membrane biology.
*Discusses the current stat of electrostatics in biomolecular
simulations and future directions
*Includes information on time and length scales in lipid bilayer
simulations
*Includes a chapter on the nature of lipid rafts
Membranes are essential cellular organelles. They not only define
cells and other organelles, but also are critical in the cell
function by selectively regulating the passage of molecules by
acting as a matrix for other signaling molecules, and as conduits
of information transfer between the external environment and the
cell interior. This series was originally added in 1970 and has
since provided a systematic, comprehensive, and rigorous approach
to specific topics relevant to the study of cellular membranes.
Each volume is a guest edited compendium of membrane biology. This
series has been a mainstay for practicing scientists and students
interested in this critical field of biology. Articles covered in
the volume include The Mechanical Properties of Bilayers; Molecular
Dynamic Modeling of MS Channels; Structures of the Prokaryotic
Mechanosensitive; Channels MscL and MscS; 3.5 Billion Years of
Mechanosensory Transduction: Structure and Function of
Mechanosensitive Channels in Prokaryotes; Activation of
Mechanosensitive Ion Channels by Forces Transmitted through
Integrins and the Cytoskeleton; Thermodynamics of
Mechanosensitivity; Flexoelectricity and Mechanotransduction; Lipid
Effects on Mechanosensitive Channels; Functional Interactions of
the Extracellular Matrix with Mechanosensitive Channels; MSCL: The
Bacterial Mechanosensitive Channel of Large Conductance; The
Bacterial Mechanosensitive Channel MscS: Emerging Principles of
Gating and Modulation; Structure function relations of MscS; The
MscS Cytoplasmic Domain and its Conformational Changes upon the
Channel Gating; Microbial TRP Channels and Their
Mechanosensitivity; MSCS-Like Proteins in Plants; Delivering Force
and AmplifyingSignals in Plant Mechanosensing; MS Channels in Tip
Growing Systems.
Current Topics in Membranes provides a systematic, comprehensive,
and rigorous approach to specific topics relevant to the study of
cellular membranes. Each volume is a guest edited compendium of
membrane biology. This series has been a mainstay for practicing
scientists and students interested in this critical field of
biology. Articles covered in the volume include ENaC Proteins in
Vascular Smooth Muscle Mechanotransduction; Regulation of the
Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids;
MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion
Channels as a Potential Mechanosensory Mechanism. Lessons From
Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity of
Voltage-Gated Channels; Hair Cell Mechanotransduction: The Dynamic
Interplay between Structure and Function; Pharmacology of Hair Cell
MS Channels; Hair Cell Mechanotransduction; Models of Hair Cell
Mechanotrasduction; Touch; Mechanosensitive Ion Channels in
Dystrophic Muscle; Mechanotransduction in Endothelial Cells;
MS Channels in Tumor Cell Migration; Mechanosensitive Channels in
Regulating Smooth Muscle Contraction in the GI; Mechanosensitive
Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.
This volume in the "Current Topics in Membranes" series discusses
the biology of chemokines and their binding partners, chemokine
receptors, in normal and disease-related states. Chemokines are
small proteins that are important in normal immune responses.
Recent research demonstrates a role for these proteins in a variety
of diseases such as heart disease, allergy, asthma, and cancer. As
a result of the discovery of this link to disease, the topic of
chemokines and drugs that block their actions has become an intense
are of study. This book presents the topics of chemokines,
chemokine receptors, and related pathologies in an integrated
manner that provides the reader with a comprehensive and up-to-date
knowledge of these topics.
* Provides a comprehensive overview of the history, molecular
biology, cell biology, pharmacology, physiology, and
pathophysiology of chemokines and their receptors
* Each chapter discusses "future directions and unanswered
questions" of chemokine biology
* Serves as a road map for future research
|
|