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Local drug delivery has gained wide acceptance as an adjunct to
mechanical debridement for the treatment of chronic periodontitis.
A variety of delivery vehicles have been utilized for intrapocket
administration of antimicrobial agents with variable success.
Varnishes, which accomplish a reservoir of drug on the tooth
surface are one of the recently developed vehicles used to deliver
antimicrobial agent such as chlorhexidine, being utilized for the
treatment of periodontitis. They allow application of a sufficient
dose of antimicrobial agent over a longer period of time. So,
varnishes seem to be an appealing vehicle for delivery of
chlorhexidine (a gold standard anti-plaque agent) in periodontal
milieu. From the results of present investigation, it can be
concluded, within limitations of the study, that multiple
applications of 1% chlorhexidine varnish have an added benefit over
single application in treatment of chronic periodontitis.
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