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This completely updated and expanded 2nd Edition provides all the
information needed in order to understand the complex molecular,
cellular and genetic mechanisms that underlie normal and abnormal
cardiac rhythms. Its goal is to help physiologists and clinicians
alike develop better preventive and treatment strategies. The
respective chapters cover a broad range of topics, including the
role of specific ion channels and transporters, gap junctions,
intracellular Ca2+ handling in pacemaker activity, impulse
conduction, and the activity of atrial and ventricular myocardium.
Special emphasis is placed on the unique electrophysiology of
specialized pacemaking cells and conducting fibers. In turn,
several types of inherited and acquired ventricular arrhythmias are
presented in detail. Clinicians will especially appreciate the
updated information on even common disorders like atrial
fibrillation and their impacts on human physiology. In closing, the
book goes “one step further” and considers future prospects,
e.g. novel antiarrhythmic agents and new concepts like
optogenetics, in the context of heart rate regulation. Accordingly,
it offers readers a solid reference guide to everything they need
to know about human heart rate and rhythm.
In his second release, A Look Inside, Crimson T Alexander has found
the path to his readers' hearts through poetry. He paints a vivid
picture of emotions and searches the depths of love in each poem. A
Look Inside shows the reader how to express care, compassion, and
courage to love their family and friends. It also has a strong
spiritual love to God that will give us all strength and hope. It
is composed of 72 poems and is divided into four sections: An Arrow
to the Heart, Broken, Spiritual Thoughts and Encouragement.
Early Childhood Jewish Education explores some of the fundamental
questions of early childhood Jewish education in today's societal,
moral, and educational debates. The book examines the challenges of
transmitting Jewish heritage using developmentally appropriate
pedagogy in the context of modern democratic society through the
lenses of multiculturalism, gender awareness, and constructivism.
Researchers from Israel and the United States consider some of the
core Jewish foundational subjects, including teaching the Bible,
holidays and ceremonies, Hebrew, Jewish literature, and
spirituality, as well as leadership issues in relation to these
contemporary debates. The book represents the ongoing collaboration
of leading researchers from Israel and the United States who have
worked together since 2010 as the International Research Group on
Jewish Education in the Early Years.
In the quarter century since Wallerstein first developed world
systems theory (WST), scholars in a variety of disciplines have
adopted the approach to explain intersocietal interaction on a
grand scale. These essays bring to light archaeological data and
analysis to show that many historic and prehistoric states lacked
the mechanisms to dominate the distant (and in some cases, nearby)
societies with which they interacted. Core/periphery exploitation
needs to be demonstrated, not simply assumed, as the
interdisciplinary dialogue which occurs in this volume
demonstrates. World-Systems Theory in Practice will appeal to
individuals with an interest in the application of WST in both the
Old World and the New World. The papers in this volume reflect the
vitality of the debate concerning the use of such generalizing
theories and will be of interest to archeologists, anthropologists,
historians, sociologists, and those involved in the study of
civilizations.
This volume provides a comprehensive and up-to-date analysis of the
source and scope of international law on migration. It explores
international norms on state authority to regulate migration,
freedom of movement, forced migration, human rights, family
unification, trafficking and smuggling of migrants, national
security, rescue at sea, health, development, integration, and
nationality. Migration and International Legal Norms shows that,
despite the absence of a comprehensive legal instrument governing
international migration, there is a wide range of legal norms
relevant to migration embodied in multilateral treaties and
conventions, regional agreements, and customary international law.
It also identifies some significant gaps in international law,
recommending areas for further cooperative efforts. This volume
will be of interest to scholars and policy-makers, and to all those
interested in how the community of nations is responding to the
increasingly significant phenomenon of international migration.
The international refugee regime is fundamentally broken. Designed
in the wake of World War II to provide protection and assistance,
the system is unable to address the record numbers of persons
displaced by conflict and violence today. States have put up fences
and adopted policies to deny, deter, and detain asylum seekers.
People recognized as refugees are routinely denied rights
guaranteed by international law. The results are dismal for the
millions of refugees around the world who are left with slender
prospects to rebuild their lives or contribute to host communities.
T. Alexander Aleinikoff and Leah Zamore lay bare the underlying
global crisis of responsibility. The Arc of Protection adopts a
revisionist and critical perspective that examines the original
premises of the international refugee regime. Aleinikoff and Zamore
identify compromises at the founding of the system that attempted
to balance humanitarian ideals and sovereign control of their
borders by states. This book offers a way out of the current
international morass through refocusing on responsibility-sharing,
seeing the humanitarian-development divide in a new light, and
putting refugee rights front and center.
Sex Differences in Cardiovascular Physiology and Pathophysiology is
a comprehensive look into the often overlooked and underappreciated
fundamental sex differences between men and women and how those
differences affect the cardiovascular system. It covers
cardiovascular function, anatomy, cell signaling and the
development of pathology. With contributions from world-renowned
research investigators, this up-to-date reference compiles critical
knowledge on cardiovascular sex differences, providing researchers
and clinicians with a better understanding of the diagnosis,
prevention and treatment of cardiovascular diseases in both men and
women.
The only comprehensive, official guide to buying and earning money
on eBay Australia Written by an eBay insider with more than ten
years of experience with the company, The New eBay guides you
through the very basics to the more complicated--from a brief
history of eBay itself to simple site navigation to every
complexity of buying and selling. Whether you just want to earn a
few dollars on the side or turn your hobby into a full-time
business, this book explains it all. Written in clear,
user-friendly language backed by simple step-by-step instructions
and helpful screen grabs from the site, the book covers everything
first-timers need to know and all the secrets experienced sellers
wish they knew. The first complete official guide for eBay
Australia written by a company insider Covers such topics as
finding items and bidding on them, pricing and listing items for
sale, accepting payments, tracking sales, logistics, customer
service, and more Perfect for every eBay user, from part-timers to
serious sellers who want to build a profitable business, The New
eBay is the ideal guide for anyone who wants to get the most out of
the world's most popular shopping and selling site.
Empress of the vast Russian Empire by the age of 33, Catherine's private and public life generated tremendous contemporary controversy, and she has subsequently been portrayed variously as a political genius, a despotic foreign adventuress, a tyrant, and a nymphomaniac. Drawing on little-known sources, including Catherine's billets doux , John Alexander has produced a much-needed balanced appraisal and popular biography of one of the most powerful, infamous, and colourful figures in modern history.
John T. Alexander's study dramatically highlights how the Russian people reacted to the Plague, and shows how the tools of modern epidemiology can illuminate the causes of the plague's tragic course through Russia. Bubonic Plauge in Early Modern Russia makes contributions to many aspects of Russian and European history: social, economic, medical, urban, demographic, and meterological. It is particularly enlightening in its discussion of eighteenth-century Russia's emergent medical profession and public health institutions and, overall, should interest scholars in its use of abundant new primary source material from Soviet, German, and British archives.
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