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Biochemical tests of fetal well-being ('placental function tests')
have been part of routine obstetric practice for more than twenty
years. This book provides an overview of the current status of
these tests - the physiological basis for their use, and their
advantages and limitations in clinical practice. Considerable
attention is given to interpretation, a subject which in the past
has led to much confusion both in the scientific literature and in
the minds of clinicians. Recent advances are described in detail,
in particular the discovery of a whole new generation of placental
products some of which offer great promise in the prediction of
conditions, such as placental abruption and premature labour, which
cannot be identified by any other current parameters. Finally, a
set of clear recommendations is put forward for the choice of test
in most of the common complications of both early and late
pregnancy. The emphasis throughout is on how the basic biology of
fetoplacental products dictates their use and interpretation in
pathological conditions.
In July 1978 a group met in Aberdeen to discuss the whole range of
new proteins recently isolated from the human placenta. With the
exception of Yuri Tatarinov all the main pioneers in the field were
present, and this book arose from the discussions which took place.
Each author was asked to bring a written man uscript corresponding
to but not necessarily identical with their verbal presentation.
Nobody was given a specified remit, for the reason that the subject
is so new that it would be impossible to design the meeting or the
book in advance. Each speaker was left free to put on display
whatever he thought was interesting or important about the newly
isolated proteins. Inevitably this has led to much overlap, since
everybody tends to follow the same path at first. Nevertheless, we
shall probably never achieve so much agreement again. Only Vernon
Stevens was set a fixed title out side the immediate field of new
placental proteins. This arose from the very exciting possibility
that the new proteins could be used to induce an autoimmune state
to products of conception and thus serve as the basis for a new
method of contraception. There are few findings at present which
bear specifically on this proposal, but the experience of Vernon
Stevens with hCG could serve as a model of the problems that might
be encountered with SP and PAPP-A."
Immunoassay procedures (isotopic and non-isotopic) have become one
of the single most important techniques in present-day diagnostic
medicine. This book is designed as an introductory test for the
staff of clinical research laboratories who conduct or intend to
conduct such techniques, and will be of great value to the
clinicians who make use of such services. The volume takes a
three-pronged approach in it's in-depth presentation: explanation
of the basic principles and applications of radioimmunoassays and
non-isotopic immunoassays; practical illustrations of the various
steps involved in immunoassays; discussion of the problems and
pitfalls in immunoassays and how to avoid them. This fifth revised
edition is a worthy successor to it's predecessors in this famous
"Laboratory Techniques" series.
Immunoassay procedures (isotopic and non-isotopic) have become one
of the single most important techniques in present-day diagnostic
medicine. This book is designed as an introductory test for the
staff of clinical research laboratories who conduct or intend to
conduct such techniques, and will be of great value to the
clinicians who make use of such services. The volume takes a
three-pronged approach in it's in-depth presentation: explanation
of the basic principles and applications of radioimmunoassays and
non-isotopic immunoassays; practical illustrations of the various
steps involved in immunoassays; discussion of the problems and
pitfalls in immunoassays and how to avoid them. This fifth revised
edition is a worthy successor to it's predecessors in this famous
"Laboratory Techniques" series.
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The Uterus (Paperback)
T. Chard, J. G. Grudzinskas
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R2,616
Discovery Miles 26 160
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Ships in 10 - 15 working days
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This important new volume in the series Cambridge Reviews in Human
Reproduction provides a wide-ranging and authoritative account of
the uterus and its physiological role in fertility, normal
pregnancy and delivery. Acknowledged authorities from around the
world provide a detailed and timely account of uterine physiology.
The volume encompasses a wealth of material including cell and
developmental biology, structure, function, anatomy and
endocrinology, and then goes on to cover clinically important
issues such as the cervix during pregnancy, measurement of uterine
contractions and initiation of labour. It will prove of particular
value to those involved in the management of women with pre-term
labour, as well as those concerned with the development of new
procedures for the prevention or amelioration of this condition.
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