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The Pasoh Forest Reserve in Malaysia is one of the most species-rich ecological systems on our planet. Since the 1970s it has been the site of intensive research on lowland tropical rain forest across a diverse range of disciplines including ecology, forestry, meteorology, and hydrology. Research has focused on biodiversity and sustainable management of tropical rain forests as well as the role of tropical rain forests in maintaining global climate and carbon sinks. This book compiles diverse studies of the ecology and natural history of the Pasoh Forest Reserve and focuses on six areas: Physical settings and environment; Vegetation structure, diversity, and dynamics; Plant population and functional biology; Animal ecology and biodiversity; Plant–animal interactions; and Anthropogenic impacts and forest management. This book is of interest to tropical forest researchers worldwide in ecology, conservation biology, taxonomy, and forestry.
The Pasoh Forest Reserve (pasoh FR) has been a leading center for
international field research in the Asian tropical forest since the
1970s, when a joint research project was carried out by Japanese,
British and Malaysian research teams with the cooperation of the
University of Malaya (UM) and the Forest Research Institute (FRI,
now the Forest Research Institute Malaysia, FRIM) under the
International Biological Program (IBP). The main objective of the
project was to provide basic information on the primary
productivity ofthe tropical rain forest, which was thought to be
the most productive of the world's ecosystems. After the IBP
project, a collaborative program between the University of Malaya
and the University of Aberdeen, Scotland, UK, for post-graduate
training was carried out at Pasoh. Reproductive biology of so me
dipterocarp trees featured in many of the findings arrived at
through the program, contributing greatly to progress in the
population genetics of rain forest trees. Since those research pro
grams, apart of the Pasoh forest and its field research station
have been managed by FRIM. In 1984, FRIM started a long-term
ecological research program in Pasoh FR with the Smithsonian
Tropical Research Institute (STRI) and Harvard University,
establishing a 50-ha plot and enumerating and mapping all trees 1
cm or more in diameter at breast height. A recensus has been
conducted every 5 years.
Contents: T. Okuda, T. Yoshida, T. Hatano: Hydrolyzable Tannins and
Related Polyphenols. - R.G. de Souza Berlinck: Some Aspects of
Guanidine Secondary Metabolites. The volumes of this classic
series, now referred to simply as "Zechmeister" after its founder,
L. Zechmeister, have appeared under the Springer Imprint ever since
the series' inauguration in 1938. The volumes contain contributions
on various topics related to the origin, distribution, chemistry,
synthesis, biochemistry, function or use of various classes of
naturally occurring substances ranging from small molecules to
biopolymers. Each contribution is written by a recognized authority
in his field and provides a comprehensive and up-to-date review of
the topic in question. Addressed to biologists, technologists, and
chemists alike, the series can be used by the expert as a source of
information and literature citations and by the non-expert as a
means of orientation in a rapidly developing discipline.
The first useful antibiotic found by screening was streptomycin.
The late Prof. WAKSMAN started screening for antibacterial
antibiotics in 1940 and, after finding actinomycin in 1941, he and
his collaborators discovered streptomycin in 1944. This antibiotic
made a great contribution in saving human lives from tuberculosis
and acute serious infections. About 1957, after wide usage of such
antibiotics as penicillin, streptomycin, chloramphenicol,
tetracycline, and erythromycin, staphy- lococci and Gram negative
organisms resistant to all or most antibiotic drugs ap- peared in
hospital patients. The origin and treatment of such resistant
strains be- came a major topic of investigation. At that time,
kanamycin was discovered and used in the treatment of resistant
infections. It may be said that the appearance of resistant strains
stimulated a resurgence of research on new antibacterial antibiot-
ics and their derivatives. In 1965, kanamycin-resistant strains
were found in hospital patients and, undertaking the study of the
mechanisms of resistance, I found that resistant strains produce
intracellular enzymes that can transfer either the terminal phos-
phate of ATP or the acetate of acetyl-CoA to the 3' -hydroxyl or
the 6' -amino group of 2-deoxystreptamine~containing antibiotics.
These results, reported in 1967, made it possible to design new
synthetic derivatives that would inhibit the growth of kanamycin
resistant strains of microorganisms. Thus, a new research area was
opened: the development of aminoglycosides useful in the treatment
of drug-resis- tant infections.
This issue of Neurologic Clinics, edited by Dr. Darin T. Okuda,
focuses on Multiple Sclerosis. Topics include, but are not limited
to, Myelin and Axonal Repair Strategies in Multiple Sclerosis;
Common Clinical and Imaging Conditions Misdiagnosed as Multiple
Sclerosis; Topographical Model for Multiple Sclerosis: A Novel
Approach to Understanding Clinical Phenotypes and Disease Activity;
Incidental Anomalies Characteristic of CNS Demyelination:
Radiologically Isolated Syndrome; Pediatric Multiple Sclerosis:
From Recognition to Practical Clinical Management; Progressive
Forms of Multiple Sclerosis: Distinct Entity or Time Dependent
Phenomena; Advanced Symptom Management Strategies in Multiple
Sclerosis, Ethnic Considerations and Multiple Sclerosis Disease
Variability; The Dynamics of the Gut Microbiome in Multiple
Sclerosis in Relation to Disease; Spinal Cord Imaging in Relation
to Clinical Status in Multiple Sclerosis, and more.
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