As imports from the People's Republic of China (PRC) have surged in recent years, posing a threat to some U.S. industries and manufacturing employment, Congress has begun to focus on not only access to the Chinese market and intellectual property rights (IPO) protection, but also the mounting U.S. trade deficit with China as well as allegations that China is selling its products on the international market at below cost (dumping), engaging in "currency manipulation," and exploiting its workers for economic gain. Members of the 109th Congress have introduced several bills that would impose trade sanctions on China for intervening in the currency market or for engaging in other acts of unfair trade, while the Bush Administration has imposed anti-dumping duties and safeguards against some PRC products and pressured China to further revalue its currency and remove non-tariff trade barriers.

The People's Republic of China (PRC) has the world's largest number of Internet users, estimated at 500 million people. Despite government efforts to limit the flow of online news, Chinese Internet users are able to access unprecedented amounts of information, and political activists have utilized the Web as a vital communications tool. In recent years, Twitter-like microblogging has surged, resulting in dramatic cases of dissident communication and public comment on sensitive political issues. However, the Web has proven to be less of a democratic catalyst in China than many observers had hoped. The PRC government has one of the most rigorous Internet censorship systems, which relies heavily upon cooperation between the government and private Internet companies. Some U.S. policy makers have been especially critical of the compliance of some U.S. Internet communications and technology (ICT) companies with China's censorship and policing activities.

Since September 2001, the United States has been concerned with radical Islamist groups in Southeast Asia, particularly those in the Philippines, Indonesia, Malaysia, Thailand, and Singapore that are known to have ties to the Al Qaeda terrorist network. Southeast Asia is a base for past, current, and possibly future Al Qaeda operations. For nearly fifteen years, Al Qaeda has penetrated the region by establishing local cells, training Southeast Asians in its camps in Afghanistan, and by financing and cooperating with indigenous radical Islamist groups. Indonesia and the southern Philippines have been particularly vulnerable to penetration by anti-American Islamic terrorist groups. Members of one indigenous network, Jemaah Islamiyah (JI), with extensive ties to Al Qaeda, are known to have helped two of the September 11 2001 hijackers and have confessed to plotting and carrying out attacks against Western targets. These include the deadliest terrorist attack since September 2001: the 12 October 2002 bombing in Bali, Indonesia, that killed approximately 200 people, mostly Westerners. On 9 September 2004, a suicide bombing attack thought to be the work of JI struck the Australian Embassy in Jakarta, killing 10 and wounding around 200. In October 2005, three suicide bombers exploded bombs within minutes of one another in Bali, killing more than 20 people. These attacks suggest that JI remains capable of carrying out relatively large-scale plots against Western targets, despite the arrest or death of hundreds of JI members, including most of its known leadership. To combat the threat, the Bush Administration has pressed countries in the region to arrest suspected terrorist individuals and organisations, deployed over 1,000 troops to the southern Philippines to advise the Philippine military in their fight against the violent Abu Sayyaf Group, launched a Regional Maritime Security Initiative to enhance security in the Straits of Malacca, increased intelligence sharing operations, restarted military-military relations with Indonesia (including restoring International Military Education and Training [IMET]), and provided or requested from Congress over $1 billion in aid to Indonesia and the Philippines. The responses of countries in the region to both the threat and to the U.S. reaction generally have varied with the intensity of their concerns about the threat to their own stability and domestic politics. In general, Singapore, Malaysia, and the Philippines were quick to crack down on militant groups and share intelligence with the United States and Australia, whereas Indonesia began to do so only after attacks or arrests revealed the severity of the threat to their citizens. That said, many governments view increased American pressure and military presence in their region with ambivalence because of the political sensitivity of the issue with both mainstream Islamic and secular nationalist groups. Indonesia and Malaysia are majority Muslim states while the Philippines and Thailand have sizeable, and historically alienated and separatist-minded, Muslim minorities.