Frovatriptan is latest molecule in category of triptans, used for migraine therapy. In spite of having great potency and tremendously long half life, this molecule is not used as first line therapy for migraine treatment because of its pharmacokinetic limitations. Preset work is an attempt to surpass the limitations associated with this molecule by delivering it through orotransmucosal route. orotransmucosal route will fasten its onset of action and will increase its bioavailability to atleast 53 %.Also, Present work have the potential to decrease the overall cost of migraine therapy and was designed after considering the complications related to acute migraine attack.

Most of the biochemical and metabolic activities have been studied in land plants and also work has been done in the case of aquatic plants especially submerged hydrophytes, hence it was considered as interest to study Hydrilla with the objectives such as physico- chemical parameters of water, growth pattern and biochemical changes of Hydrilla plant and Correlation between physico-chemical parameters of water and biological parameter of Hydrilla