Fully revised, this second edition presents trainees with the latest guidance on preparation for OSCE examinations. Comprised of fourteen chapters, the book covers all the key learning points and provides an understanding of the basic concepts behind the OSCE and advice on appropriate response. The new edition includes many new cases and covers numerous topics including genetics, neurology, drugs and vaccines, neonatology, cardiovascular system, endocrinology and much more. Enhanced by nearly 240 clinical photographs and illustrations, the book also includes multiple choice questions to help students prepare for MRCPCH and US Specialty Board examinations. Key points Fully revised, new edition providing guidance on preparation for OSCE examinations Includes multiple choice questions to help revision for MRCPCH and US Specialty Board exams Enhanced by nearly 240 clinical photographs and illustrations Previous edition (9789350251553) published in 2010

Interim remedies and provisional measures are a critical component of civil/commercial litigation and arbitration. The objective of this book is to set out not just the law and practice in relation to the primary interim remedies and preservation measures available in England & Wales and China, but also to provide the comparative analysis between the two jurisdictions concerning these interim measures. The system for interim remedies in England & Wales is well-established, but preservation measures in China are a work in progress and many differences exist between the two legal systems, both in terms of theory and practice. For example, China does not recognise the general concept of interim measures, if looked at from the English law point of view, though it does have similar concepts of Property preservation, evidence preservation and behaviour preservation. China has recently adopted Chinese Civil Code 2020 and in writing this book the authors have incorporated all the relevant elements from the new Code. There is no equivalent of Practice Directions in China, and this book provides provide much needed clarity on this area, drawing together the law and guidance which is presently scattered across numerous local courts in the different provinces. This is an important book that is likely to have a significant impact on existing scholarship regarding interim remedies in England, Wales and China, and be of interest of all parties involved in cross-border litigation. Its readership will include industry professionals, academics, policy-makers and government officials.

This book covers innovative breakthroughs in additive manufacturing processes used for biomedical engineering. More and more, 3D printing is selected over traditional manufacturing processes, especially for complex designs, because of the many advantages such as fewer restrictions, better production cost savings, higher quality control, and accuracy. Current challenges and opportunities regarding material, design, cost savings, and efficiency are covered along with an outline of the most recent fabrication methods used for converting biomaterials into integrated structures that can fit best in anatomy while still obtaining the necessary architecture, mechanical reliability, biocompatibility, and anti-bacterial characteristics needed. Additional chapters will also focus on selected areas of applications such as bionics, affordable prostheses, implants, medical devices, rapid tooling, and drug delivery. Additive Manufacturing Processes in Biomedical Engineering: Advanced Fabrication Methods and Rapid Tooling Techniques acts as a first-hand reference for commercial manufacturing organizations which are mimicking tissue organs by using additive manufacturing techniques. By capturing the current trends of today's manufacturing practices this book becomes a one-stop resource for manufacturing professionals, engineers in related disciplines, and academic researchers.

Low sleep quality, sleep disturbances, and at least occasional sleep dissatisfaction are prevalent among most college undergraduates. Poor academic performance, depressed mood, irritation during the day and daytime sleepiness is the consequences of insufficient sleep. A survey was performed in Banasthali pharmacy students by distributing a sleep related questionnaire to students. The questionnaire included questions about demographic characteristics, sleep and daytime habits, lifestyle and academic progress and effect of course curriculum on sleep quality. Statistical analysis was performed with the help of the SPSS 16.0 software package. Relationship between sleep quality, night time and daytime habits, sleep problems, age and BMI were studied using the Spearman Rank Order Correlations.

Oracle e-Business Suite Payroll R12 is written for new and intermediate users, key-users and administrators. It focuses on your role in an Oracle eBS-environment and explains the Concepts, describes the main Screens, gives Step-by-Step instructions with navigation paths and has a Glossary and FAQ-list. All chapters have Questions and Answers. The book has six chapters, 81 pages and has lots of screenshots and illustrations. With this book you learn the main concepts like: Assignment and Consolidation Sets, Defining a new Payroll, running a Payroll run, Balance Feeds and Balance Dimension, Batch Element Entry, Conversion Rate Types, Costing, Reversing and Advance pay Period. And the most important flows including their steps are also described for you, like: Reverse a Payroll, Voiding a Check, Transfer to GL Flow and Setting Up the Payslip. This is just a small list of all the concepts, screens and flows described in this book. What do eBS users think about these books? "Very well structured and easy to follow, even for beginners. " John M. McNamara - Wokingham Borough Council "Highly informative and exemplary, hats off." Sunil Sunder Rao - Apps DBA "I am really happy that I found these books." Peter Lung - Consultant

Antimicrobial resistance is now threatening the management of infections such as pneumonia, tuberculosis, malaria and AIDS.So at present scenario there is a great need for developing new anti-infective agents.Heterocycles are an inescapable and integral feature of numerous diverse branches of chemistry.The presence of heterocycles in all kinds of organic compounds of interest in biology, pharmacology, optics, electronics, material sciences.Among the heterocyclic compounds, five member heterocyclic moieties fused with aromatic ring system with various heteroatom like N, S, and O have possess wide spectrum of pharmacological activity.a variety of Schiff bases derivatives of sulfonamides have been successfully synthesized in appreciable yields and screened in vitro for their antimicrobial activities against both strains of Gram-positive and Gram-negative bacteria. Moreover, structure-activity relationship studies revealed that the 4-chloro benzaldehyde along with sulfamethoxazole Schiff base is more active as antimicrobial agent as compared to 2-chloro and 3-bromo derivatives but other derivative like salicyldehyde, anisaldehyde also possesses moderate activity.

The resistance of malaria parasites to widely used drugs prompted an upsurge in the development of new drugs with novel mechanism of action, and re- evaluation of the existing drugs to overcome the resistance problem. A number of new potential target pathways have already been identified and efforts to develop lead compounds for these putative targets hopefully will allow treatment of malaria infections in a uniform sustained way. Considerable research efforts were directed in the areas of chloroquine drug resistance reversal agents. Careful development of some bisquinolines, which are free of toxic side effect, 4-anilinoquinolines and modified chloroquine analogs may be helpful to obtain drug candidates that inhibit the growth of chloroquine sensitive and resistant parasites. In the past several years, new structural classes of antimalarial agents, target based antimalarial agents, iron chelators have made some interesting and promising lead molecules available for further optimization to provide compounds for clinical development.

Pulsatile Drug Delivery Systems are gaining a lot of interest as these systems deliver the drug at specific time as per the pathophysiological need of the disease, thus providing spatial and temporal delivery and increasing patient compliance. Diseases wherein such delivery systems are promising include asthma, peptic ulcer, cardiovascular diseases, arthritis, attention deficit syndrome in children, and hypercholesterolemia. This book will cover various approaches that have been developed to control drug delivery profile with different polymeric systems like time controlling, internal stimuli induced (temperature induced and chemical stimuli-induced), external induced (magnetic fields, ultrasound, electric fields and light stimulation) and Multiparticulate system. Special attention have been made towards recent advances, patents, future opportunity and major challenges regarding formulation of pulsatile drug delivery of oral dosage forms and are summarized and discussed.

This book gives readers an in-depth analysis of the fundamentals behind designing on-demand medium access control (MAC) protocols for multihop wireless networks, esp. with nodes having multiple antenna technologies. This is the first attempt towards designing and analyzing on-demand, also known as contention-based, MAC protocols for multiple beam smart antennas (MBSA). The book begins with a general introduction of the state-of-art problems and solutions that then forms the basis of this book. The book then introduces mathematical models to analyze MBSA and derive basic MAC fundamentals. The readers are then exposed to step-by-step MAC design for MBSA in wireless ad hoc networks. Once the basic design is completed, advanced concepts such as wireless mesh network architecture, Quality of Service (QoS), interoperability with existing IEEE802.11 standards and co-existence with other antenna technologies, viz., omnidirectional and directional, are introduced. Finally, the book ends with introducing link layer reliable and energy-efficient communication mechanisms for wireless sensor networks.

The objective of this work is to study the response of this neutrophile in an acidic environment with respect to the activities of isocitrate, malate, succinate and G-6-PD on being coupled to the electron transport chain. E.coli have an optimum pH range of 6 to7 for growth and survival and are hence, called neutrophiles. When challenged by low pH, protons enter the cytoplasm; as a result mechanisms are required to alleviate the effects of lowered cytoplasmic pH. This study highlights new insights into activities of isocitrate, succinate, malate and G-6-PD, coupled to the electron transport chain by the reducing power, as yet another system possessed by E.coli as an armor against harsh acidic environments. The activities of dehydrogenases in acid shocked cells were monitored at intervals of 1, 2, 3 and 4 h at different pH and then compared with their activities at pH 7 (taken as control). Acid stressed microorganisms are an economically important group. Acid stable enzymes with applications as lubricants and catalysts. Improvement of strains can be done by studying the acid tolerance of microorganisms in fermentation broth to increase product yield.