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Organ transplantation has almost disappeared from headlines in the
daily press, possibly because it failed to fulfill exaggerated
expectations. Transplanta tion pathology has become more and more
important, not only with relation to therapeutic transplantations
but even more in its fundamental theories. There is some analogy
here to the development in space science where spectacular
achievements were followed by sobering frustrations and where, for
the time being, the effect on technology is more fruitful than the
outcome of the original far-reaching projects. That transplant
rejection was defined, in most of its stages, as an immunologic
process, has given many new impulses to immunology in general.
Transplantation assays have become a pet experiment in
immunobiology and an abundant source of general information and
knowledge. The implications of such a development could not be
predicted when the present volume was outlined and planned. In
accordance with the concept of WILLI MASSHOFF, general
transplantion pathology was given a central position as a
fundamental science, while the chapters on the transplantation of
various tissues are of a more paradigmatic character. It was
MASSHOFF who invited competent authors and who managed to balance
their articles, despite some overlapping, so as to draw a
comprehensive picture of contemporary transplanta tion pathology.
WILLI MASSHOFF died while he was editing the first manuscripts. As
co-editors we have undertaken to complete the publication that we
began together."
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